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Test 2
Week 3, 4, & 5 (Psychopharm, Schizophrenia, and Anxiety/Somatoform)
78
Nursing
Undergraduate 3
06/25/2013

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Cards

Term
What assessment data would be most significant for a patient with temporal lobe damage?
Definition
Assess for visual and auditory aphasia. Test if they can understand speech and writing.
Term
What function should the nurse assess for a patient with limbic system damage?
Definition
Test memory consolidation (short to long term), emotional capacity, and motivational behaviors
Term
If a patient has lesions of the basal ganglia, what observations would the nurse expect to make?
Definition
Basal ganglia is responsible for controlling precise, voluntary movements and stabilizing motor movements. Lesions result in abnormal motor movement such as in Parkinson's disease and Huntington's disease. Lesions of basal ganglia dysfunction occur while at rest.
Term
What symptoms would a nurse expect to find in a person with a cerebellar lesion?
Definition
The cerebellum coordinates muscle synergy and acitvity but does not initiate movement. Lesions of the cerebellum produce intention tremors on the same side of the body as the lesion. The motor dysfunction occur when the person is attemptign to move.
Term
Explain the function of the reticular activating system.
Definition
-Integrates info from sensory pathways and projects to areas like thalamus and hypothalamus.
-Screening device that allows individuals to tune in some stimuli and out others
-Allows humans to fall asleep (when turned off = coma)
Term
What part of the nervous system do anticholinergic medications inhibit? For what signs and symptoms should the nurse be alert?
Definition
The parasympathetic nervous system is being inhibited. Anticholinergic cause dilated pupils, decreased lacrimation, dry mouth, tachycardia, and slowing of bowels and bladder.
Term
What is the role of dopamine?
Definition
Located primarily in brain stem.
-Sythesized by tyrosine (dietary amino acid)
-MOA: excitatory
-Controls complex movements, involved in motivation and cognition, regulates emotional response
-Implicated in schizophrenia and movement disorders
-IMPORTANT: antipsychotic meds work by block the dopamine receptors and reducing dopamine acitivity
Term
What is the role of norephinephrine?
Definition
Most prevalent NT in the NS
-MOA: excitatory
-Causes changes in attention, implicated in learning adn memory, sleep and wakefulness, mood
-Primarily located in the brain stem
-Deficit of NE is implicated in anxiety disorders and depression and social withdrawal and memory loss
Term
What is the role of serotonin?
Definition
MOA: inhibitory
-Only found in the brain (no way to test how much so we give meds and see if there is an improvement
-Associated with depression
-Synthesized from tryptophan, a dietary amino acid
-Wakefulness, sleep, mood, sexual behaviors, regulates emotions
Term
What is the role of acetylcholine?
Definition
MOA: excitatory or inhibitory
-Found in brain, spinal cord, and peripheral nervous system (particularly plentiful in neuromuscular junction in skeletal muscle)
-Synthesized from dietary intake of choline (red meat)
-Signals muscles to become more alert, controls sleep and wakefulness
-Important in psychiatry because people with alzheimers have low acetylcholine levels, muslces arent alert
Term
What is the role of GABA?
Definition
MOA: Major inhibitory NT in brain
-Amino acid
-Modulates the other neurotransmitters (does not provide direct stimulus)
Term
Why does enlargement of ventricles in the brain occur?
Definition
-Blockage of CSF outflow from within or from the brain
-Overproduction of CSF
-Brain atrophy resulting from the health of large numbers of cortical neurons
-Neurodevelopemental problems
-Enlarged ventricles associated with schizophrenia and alzheimers
Term
What is the significance of the extrapyramidal system in movement disorders associated with psychotropic drug use?
Definition
Any significant increase or decrease in the level of dopamine can result in extrapyramidal motor changes. Psychotropic drugs reduce the amount of dopamine in the brain. The substantia nigra and the basal ganglia use dopamine to communicate about the ongoing motor activity from the body, so when dopamine is reduced this communication is reduced causing Parkinson's like symptoms.
Term
What do SSRIs do generally?
Definition
Antidepressants, selectively inhibit serotonin reuptake to increase amount that stays in synaptic cleft
Term
What do Antipsychotics do generally?
Definition
Block dopamine receptors
Term
What do antianxiety medications do generally?
Definition
Increase GABA
Term
What are 3 objectives for nurses administering psychotropic drugs?
Definition
1. Reduce symptoms
2. Control Side effects
3. Proper education promoting adherence
Term
How is the length of the washout period calculated before a new psychotropic drug can be administered?
Definition
If a nurse gives the same drug dose at the same time, a steady state is achieved in four half lives. When discontinuing a drug, four half-lives are required to eliminate 96% of the drug. This period is referred to as the washout period.
Term
Describe the anatomic dimension of the blood-brain barrier?
Definition
Structure of the capillaries that supply blood to brain and prevent many molecules from slipping through, there are no gaps
Term
Describe the physiologic dimension of the blood-brain barrier.
Definition
Chemical and transport system that recognizes and then allows certain molecules into the brain
-Lipid solubility important in determining if it can enter the brain
-Only drugs that are able to pass thorugh are effective in treating psychiatric disorders
Term
Describe the metabolic dimension of the blood-brain barrier.
Definition
Prevents molecules from entering by enzymatic action within the endothelial lining of the brain capillaries.
Term
Common reasons that psychiatric patients give for not complying with prescribed drug treatment regimens.
Definition
-Sexual dysfunction
-Specific side effects
-Emotional dulling
-Cognitive slowing
-Denial of need
-Fear of becoming addicted
-Religious reasons
-Interferes with work
Term
What are 6 areas for discussion when a nurse is giving medication education?
Definition
1. Side effects
2. Discuss safety issues
3. Attitude of patient and nurse about medications
4. Drug interactions
5. Instructions for older adult patients/pregnant or breast feeding patients
6. Awareness of metabolic differences in diverse races and ethnicities
Term
Sociogenic theory of understanding schizophrenia
Definition
People who live in inner cities with fewer opportunities and lower education, have fewer rewards, that their lives are so stressful that they can develop schizophrenia
Term
Describe reactive psychosis theory of understanding schizophrenia.
Definition
One time exposure to reactive event
Term
Describe biologic theory of understanding schizophrenia.
Definition
People with genetic predisposition for schizophrenia
Term
What is the difference between positive and negative symptoms of schizophrenia?
Definition
Positive symptoms: deviant behaviors are presents
Negative symptoms: normal behaviors are absent, much poorer prognosis than positive symptoms
Term
What are the five DSM IV subtypes of schizophrenia?
Definition
1. Catatonic: Mutism and Hyperexcited
2. Disorganized
3. Paranoied: Persecution and Grandiosity/Delusions
4. Undifferentiated
5. Residual: characteried by one previous episode
Term
What is the physiologic difference between positive (type I) and negative (type II) schizophrenic symptoms?
Definition
Positive (type I)-Believed to be result of elevated dopamine levels affecting the limbic areas of the brain
Negative (type II)-Related to hypodopaminergic process. Can be caused by cortical structural changes.
Term
Schizoaffective disorder
Definition
Characterised by both affective and schizophrenic symptoms with substantial loss of occupational and social functioning.
Term
Delusional disorder
Definition
Display similar to schizophrenia but delusions have a basis in reality.
-Patients have never met criteria for schizophrenia
-Behavior is relatively normal except in relation to delusions
-Symptoms are not the result of a substance-induced or medical condition
Term
Brief psychotic disorder
Definition
Includes all psychotic disturbances that last less than 1 month and are not related to a mood disorder, a general medical condition or a substance induced disorder.
Term
Schizophreniform disorder
Definition
Displays symptosm that are typical of schizophrenia and last at least 1 month but no longer than 6 months. This cautious approach spares tha individual the lifelong diagnosis of schizophrenia
Term
What 3 groups are personality disorders clustered into?
Definition
1. Cluster A: Characterized by schizoid, odd, eccentric behaviors
2. Cluster B: Characterized by dramatic, emotional, or erratic behaviors
3. Cluster C: Characterized by anxious or fearful behaviors
Term
Hallucination
Definition
False sensory perceptions not associated with real external stimuli, might involve any of the five senses
Term
Delusion
Definition
Fixed, false belief, not consistent with the person's intelligence and culture; unamenable to reason
Term
Anergia
Definition
Absence of energy cause by changes in brain chemistry, anatomy, or both
Term
Anhedonia
Definition
Loss of pleasure in activities or interests previously enjoyed; a symptom noted in depression and schizophrenia
Term
Clang
Definition
Words similar in sound, but not in meaning, that conjure up new thoughts
Term
Echolalia
Definition
Psychopathologic repeating words of one person by another; noted in types of schizophrenia
Term
Echopraxia
Definition
Imitation of the body position of another
Term
Neologism
Definition
new word created by the patient for psychological reasons; noted in some types of schizophrenia
Term
Traditional antipsychotic drugs
Definition
Developed between 1950 and 1990, and are further divided based on potency. Essentially, the effects of traditional antipsychotics are r/t the blockade of a specific dopamine receptor
Term
Atypical antipsychotics
Definition
Newer agents from 1990 on. These agents are referred to as atypical because of the following characteristics: reduced or no risk for EPSEs, increased effectiveness in treating negative symptoms, minimal risk of tardive dyskinesia, reduced or no risk of elevated prolactin.
Term
4 dopamine tracts
Definition
Tract 1: Nigrostratal tract involved in movement and extrapyramidal disorders
Tract 2: Tuberoinfundibular tract modulates pituatary function and involved in neuroendocrine control and raised prolactin levels
Tract 3: Mesolimbic tact involved in emotional and sensory
Tract 4: Mesocortical tract involved in cognitive process
Term
What are concerns when taking Clozapine?
Definition
Can cause agranulocytosis, a potentially fatal illness
Term
What are the indications for use of benzodiazepines?
Definition
They reduce anxiety, promote sleep, and can produce hypnosis and amnesia
Term
What is the difference between Buspirone and benzodiazepines?
Definition
Unlike Benzos, Buspirone is not sedating, does not cause a high so has little abuse potential, has no cross-tolerance with sedatives or alcohol, does not produce dependence, withdrawal, or tolerance; but Busprione has delayed onset of antianxiety effect compared with benzodiazepines.
Term
What difference in drug metabolism makes lorazepam and oxazepam good choices for treating anxiety in older adult patients?
Definition
The metabolites in these drugs are inactive so the effects of the drug do not persist.
Term
Discuss the nursing care that would be provided to a patient who has overdosed on benzodiazepines and alcohol.
Definition
Effective overdose treatment begins with emptying the stomach by induced vomiting and gastric lavage, followed by activated charcoal. The nurse should monitor BP, Pulse, and respirations and provide supportive care as indicated
Term
What specific interventions would be necessary if the patient receives flumazenil (Romazicon)?
Definition
A response to flumazenil typically occurs within 30 to 60 seconds. 2 important considerations are that 1) it does not speed up the metabolism or excretion of benzodiazepines and 2) it has a short duration of action, so the patient could recover only to return to a preflumazenil state if not monitored by nurse
Term
What makes the use of SSRIs attractive for the treatment of anxiety disorders?
Definition
SSRI effectiveness in panic and other anxiety disorders can be partially explained by serotonin’s role in up-regulating GABA transmission in the prefrontal cortex. By up-regulating inhibitory neurons, a more inhibitory effect can be expected
Term
Anxiety disorders
Definition
Patterns of symptoms and behaviors in which anxiety is either the primary disturbance or a second problem that is recognized when the primary symptoms are removed
Term
Somatoform disorders
Definition
Patients have physical symptoms for which there is no known organic cause or physiologic mechanism
Term
Dissociative disorders
Definition
Mental states where identity, memory, or consciousness is disturbed or altered.
Term
Primary gain
Definition
Positive internal motivations for a patient to report symptoms (medical reason to justify being unable to perform a task patient will feel better)
Term
Secondary gain
Definition
Positive external motivations that a patient may have for reporting symptoms (missing work, obtaining drugs
Term
Identify a comprehensive list of nursing measures to relieve anxiety
Definition
1. Provide a calm and quiet environment
2. Ask patients to identify what and how they feel
3. Encourage patients to describe and discuss their feelings
4. Help patients identify possible causes of their feelings
5. Listen carefully for patients’ expressions of helplessness and hopelessness
6. Ask patients whether they feel suicidal or have a plan to hurt themselves.
7. Plan and involve patients in activities such as going for walks and playing recreational games.
Term
Describe nursing interventions to help patients replace dysfunctional coping methods with effective coping strategies
Definition
• Discuss with patients their present and previous coping mechanisms.
• Discuss with patients the meaning of problems and conflicts
• Use supportive confrontation and teaching.
• Assist patients with exploring alternative solutions and behaviors.
• Encourage patient to test new adaptive coping behaviors through role-playing or implementation.
• Teach patients relaxation exercises.
• Promote the use of hobbies and recreational activities
Term
Identify specific nursing interventions for a patient experiencing a panic attack
Definition
1. Stay with the patient who is having a panic attack, and acknowledge the patient’s discomfort.
2. Maintain a calm style and demeanor.
3. Speak in short, simple sentences, and give one direction at a time in a calm tone of voice.
4. If the patient is hyperventilating, provide a brown paper bag and focus on breathing with the patient.
5.Allow patients to pace or cry, which enables the release of tension and energy.
6. Communicate to patients that you are in control and will not let anything happen to them.
7. Move or direct patients to a quieter, less-stimulating environment. Do no touch these patients; touching can increase feelings of panic.
8. Ask patients to express their perceptions or fears about what is happening to them
Term
Identify key nursing interventions for a patient with obsessive-compulsive disorder
Definition
1. Ensure that basic needs of food, rest, and grooming are met.
2. Provide patients with time to perform rituals.
3. Explain expectations, routines, and changes.
4. Be empathic toward patients and be aware of their need to perform rituals.
5. Assist patients with connecting behaviors and feelings.
6. Structure simple activities, games, or tasks for patients.
7. Reinforce and recognize positive nonritualistic behaviors.
Term
Discuss key nursing interventions for a patient with ASD or PTSD
Definition
1. Be nonjudgemental and honest; offer empathy and support; acknowledge any unfairness or injustices related to the trauma.
2. Assure patients that their feelings and behaviors are typical reactions to serious trauma.
3. Help patients recognize the connections between the trauma experience and their current feelings, behaviors are typical reactions to serious trauma.
4. Help patients evaluate past behaviors in the context of the trauma, not in the context of current values and standards.
5. Encourage safe verbalization of feelings, especially anger.
6. Encourage adaptive coping strategies, exercise, relaxation techniques, and sleep-promoting strategies.
7. Facilitate progressive review (imaginal or in vivo) of the trauma and its consequences.
8. Encourage patients to establish or reestablish relationships
Term
Devise a general list of nursing interventions for patients with somatoform disorders
Definition
1. Use a matter-of-fact, caring approach when providing care for physical symptoms.
2. Ask patients how they are feeling, and ask them to describe their feelings.
3. Assist patients with developing more appropriate ways to verbalize feelings and needs.
4. Use positive reinforcement, and set limits by withdrawing attention from patients when they focus on physical complaints or make unreasonable demands.
5. Be consistent with patients, and have all requests directed to the primary nurse providing care.
6. Use diversion by including patients in milieu activities and recreational games.
7. Do not push awareness of or insight into conflicts or problems.
Term
Histamine
Definition
Neuromodulator
-Role in allergic response, GI secretions
-Some psychiatric meds blocks histamine, which causes sedation, weight gain, and hypotension
Term
Neuropeptides
Definition
Endorphins and Enkephalins, Substance P, Somatostatin
Term
Ventricles
Definition
4 spaces within the brain
Term
Frontal lobe
Definition
Sense of smell
Motor control
Higher mental ability
Expressive language
Term
Parietal lobe
Definition
Sensation such as touch, temperature pressure, pain
Term
Occipital lobe
Definition
Interpreting visual stimuli and information
Term
Temporal lobe
Definition
Hearing/language
Term
Cerebellum
Definition
Posture, coordination, muscle tone, memory of skills/habits
Term
What are 3 important facts about schizophrenia?
Definition
1. High probability that it will become apparent in late adolescence or early adulthood remember it appears early, often seen in adolescence when brain maturation is nearly complete.
2. Stress is believed to play a role in onset and relapse
3. Dopamine antagonist drugs are therapeutically effective
Term
What are the 3 phases of schizophrenia?
Definition
1. Acute phase with severe symptoms
2. Stabilizing phase in which patient improves
3. Stable phase in which symptoms might still be present but are not as severe and disabling
Term
What are common stressors that trigger schizophrenia?
Definition
1. Biologic: medical illness
2. Psychosocial: loss of a relationship
3. Sociocultural: homelessness
4. Emotional: persistent criticism
Term
Akathisia
Definition
Motor restlessness, generally expressed as the inability to sit still caused by the dopamine blockade by ceratin types of neuroleptic medications (an extrapyramidal side effect)
Term
Dyskinesia
Definition
Disturbed disorientation and motor activity, usually producing a jerky motion; an EPSE of neuropleptic medications related to their effect on dopamine receptors
Term
Tardive dyskinesia
Definition
Extrapyramidal syndrome that usually emerges late in the course of long term antipsychotic drug therapy; includes grimacing, buccolingual movements, and dystonia; might be irreversible
Term
neuroleptic malignant syndrome
Definition
A serious adverse effect of antipsychotic drugs. The nurse should routinely assess for NMS by taking the patient's temp and evaluating rigidity and tremors.
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