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Neuroscience Test 2
Visual Cortex, Parallel Processing, Retinal A&P, etc,
98
Biology
Undergraduate 3
03/19/2013

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Cards

Term
Define LGN:
Definition
Lateral geniculate nucleus; dorsal; where retinal ganglion cells synapse @ midbrain; 2 ventral magno & 4 dorsal parvo
Term
Midget ganglion cells project to what LGN layers?
Definition
3, 4, 5, 6
Term
Damage to the right LGN layers 3, 4, 5, and 6 decreases _____________ field.
Definition
color and acuity in the left
Term
Injury to the left LGN layers 1 and 2 decreases ___________ field.
Definition
motion in the right
Term
The area of the visual field in which light alters the response of the cell is?
Definition
the receptive field
Term
Spatial (center-surround) antagonism is critical for detecting light intensity ____________.
Definition
differences
Term
the LGN has 6 layers from...?
Definition
bottom to top
Term
What type of cells send neural signals using action potentials?
Definition
amacrine
Term
What other type of cells send neural signals using action potentials?
Definition
ganglion
Term
Parasol cells are?
Definition
colorblind
Term
_________ protein in photopigment determines its wavelength sensitivity.
Definition
opsin
Term
Most V1 cells are?
Definition
binocular
Term
Both _______ and _________ process information from eye to brain.
Definition
serial & parallel
Term
What type of ganglion cell is 10%, responsible for motion in periphery, and the "where it is" component?
Definition
parasol
Term
What is the light-catching chromophore in photopigment?
Definition
retinal
Term
What ganglion cells show spatial and chromatic antagonism?
Definition
parvo
Term
Hyperpolarization of rods and cones causes a ___________ in glutamate release.
Definition
decreases
Term
What type of ganglion cell is 80%, processes color, and has a sustained firing rate?
Definition
midget
Term
The Magno ganglion cells project to _________ LGN layers 1 and 2.
Definition
ventral
Term
Spatial antagonism was first present in what cells?
Definition
bipolar cells
Term
The photoreceptor resting potential is _____________ or less hyperpolarized than most nerve cells.
Definition
more depolarized
Term
In the absorption of a photon, the rhodopsin photoisomerizes from...?
Definition
11 cis to all trans
Term
The transducin dis-inhibits or activates phosphodiesterase, which catalyzes the conversion of...?
Definition
cyclic GMP to GMP
Term
What are the V1 layers?
Definition
1 to 6 top to bottom
Term
A _________ bipolar cell has a depolarizing excitatory response if light is increased in the center and decreased in the surround.
Definition
on center
Term
What is graded in amplitude according to stimulus intensity?
Definition
Graded Potential
Term
The parvo ganglion cells are the "_____________" component.
Definition
"What it is."
Term
What fits within the skull due to sulci (furrows) and gyri (ridges)?
Definition
the cortex
Term
Rods and Cones __________ in response to light.
Definition
Hyperpolarize
Term
This type of bipolar cell has a depolarizing excitatory response if light is decreased in the center and increased in the surround.
Definition
off center
Term
The left LGN layers 2, 3, and 5 receive from...?
Definition
the left temporal retina
Term
V1 neurons are ______________ and 20% inhibitory.
Definition
80% excitatory
Term
What type of cells send neural signals using graded potentials?
Definition
bipolar cells
Term
Most V1 cells are sensitive to...?
Definition
orientation
Term
Photoisomerization causes multiplicative activation of what enzyme?
Definition
transducin
Term
P-Ganglion cells project to _________ layers 3, 4, 5, and 6.
Definition
dorsal
Term
In a Vision Test, low contrast motion is detected in the periphery. This tests the...?
Definition
Magno pathway
Term
Rods and cones are ___________; the receptive field does not show spatial antagonism.
Definition
light detectors
Term
_____________ surface area underlies computational ability.
Definition
large cortical
Term
The left LGN layers 1, 4, and 6 receive from the...?
Definition
right nasal retina
Term
Koniocellular LGN receives input from?
Definition
S Cones
Term
What cells send neural signals using graded potentials?
Definition
cone
Term
The magno ganglion cells are the "____________" component.
Definition
"where it is."
Term
Cortical cells are sensitive to __________ of motion.
Definition
direction
Term
Parasol ganglion cells project to what LGN layers?
Definition
1 and 2
Term
Phosphodiesterase catalyzes the _________ of CGMP to GMP.
Definition
hydrolysis
Term
__________ potential is an all or nothing response.
Definition
action
Term
The rod response is limited by the ________ of sodium channels.
Definition
number
Term
Photoreceptors ____________ to light.
Definition
hyperpolarize
Term
Light photo-_________ retinal.
Definition
isomerizes
Term
Rods and cones release what?
Definition
glutamate
Term
What cells are responsible for lateral information transfer in outer/middle retina?
Definition
horizontal
Term
Define receptive field.
Definition
area of visual field w/n which light alters firing rate of cell
Term
10% of all ganglion cells:
Definition
parasol
Term
80-90% of all ganglion cells:
Definition
Midget
Term
Ganglion cells show __________ antagonism.
Definition
chromatic
Term
Increased contrast --> Increased firing...?
Definition
frequency
Term
Increased light to surround of an on-center ganglion cell will ___________ the cell.
Definition
inhibit
Term
center-surround cells are stimulated by __________ rather than absolutes.
Definition
differences
Term
________ ganglion cells have a transient response.
Definition
Magno
Term
What are the 1st retinal cells to signal with action potentials?
Definition
amacrine
Term
Bistratified ganglion cells:
Definition
S cones
Term
Four ________ parvocellular layers to LGN.
Definition
dorsal
Term
Another name for Midget cells:
Definition
Parvo
Term
Another name for Parasol cells:
Definition
Magno
Term
X cells are sensitive to position or...?
Definition
Phase
Term
There is evidence for defect in M-pathway in what disorder?
Definition
dyslexia
Term
_____________ input to LGN layers 2, 3, and 5.
Definition
ipsilateral
Term
____________ input to LGN layers 1, 4, and 6.
Definition
contralateral
Term
M cells do not respond to ________ patterns.
Definition
isoluminant
Term
Two _________ magnocellular layers.
Definition
ventral
Term
Compared to the skull, the surface area of the cortex is much?
Definition
greater
Term
more than _______ of V1 devoted to macula.
Definition
half
Term
over representation of central field = corical _____________.
Definition
magnification
Term
Layers 2 and 3 of V1 project to?
Definition
extrastriate
Term
Layers 5 and 6 of V1 project to?
Definition
LGN
Term
Unlike most V1 cells, 1st cells in 4C to receive LGN input are?
Definition
monocular
Term
Modular component of cortical neurons:
Definition
hyper column
Term
M and P streams make specific connections to blobs and _______ space.
Definition
interblob
Term
Many V1 cells respond best to stimulation of non-corresponding points. This is known as retinal ___________.
Definition
disparity
Term
The best stimulus for an off center cell is...?
Definition
a decrease of light in the center and an increase of light in the surround
Term
What are the events that occur after the absorption of light by rhodopsin in the retina:
Definition
  • photoisomerizes 11-cis retinal to all trans
  • multiplicative activation of transducin
  • dis-inhibition (activation) of phosphodiesterase
  • lconversion of cGMP to GMP
  • closure of outer segment Na+ channels
  • hyperpolarizing current spreads to receptor terminal endings decreasing release of glutamate from receptors
Term
most midget ganglion cells show:
Definition
  • color opponency
  • comprise the majority of ganglion cells
  • synapse in 4 dorsal layers of LGN
  • aka P or parvo cells
Term
Parasol ganglion cells show:
Definition
  • transient firing rate
  • aka M or magno cells
  • synapse in 2 ventral layers of LGN
  • mediate motion perception
Term
a mass applying pressure to the optic chiasm from below may lead to...?
Definition
bitemporal hemianopsia
Term
Characteristics of LGN layers:
Definition
  • 1, 4, & 6 receive contralateral input from nasal retina
  • 2, 3, & 5 receive ipsilateral input from temporal retina
  • 1 & 2 receive input from parasol cells
  • 3, 4, 5, & 6 receive input from midget ganglion cells
Term
A lesion affected left LGN layers 3-6 will most likely decrease:
Definition
color vision & acuity in the right visual field
Term
What are the stimulus properties first processed in V1?
Definition
  • direction of motion
  • orientation
  • binocularity 
Term
Where do magno axons synapse?
Definition
in the upper part of layer 4C
Term
The apparent disproportinate area of V1 devoted to central vision is consistent with what?
Definition
ganglion cell distribution and numerosity
Term
Where do the nasal ganglion fibers (axons) from each eye cross & project to the contralateral (opposite side) LGN?
Definition
optic chiasm
Term
a pituitary tumor presses from below on the optic chiasm causing defects in...?
Definition
the temporal field of each eye
Term
Visual area 1 is also known as?
Definition
striate cortex, Broadmann's area 17, primary visual cortex
Term
Compare & Contrast LGN & V1:
Definition
6 layers to each, but LGN is numbered from bottom to top and V1 is numbered from top to bottom
Term
Define spatial antagonism:
Definition

conveys differences in light intensity

 

contrast; first occurs at bipolar cell level

Term
Define chromatic antagonism:
Definition
color opponency in parvo/midget cells
Term
What is new in the visual cortex in terms of information processing?
Definition
binocular, orientation, direction of motion
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