Term
| The extracellular side of a plasma membrane contains this kind of molecule |
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Definition
| The glycocalyx is found here |
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Term
| The components and function of glycocalyx |
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Definition
| They are made of a layer of carbohydrates made of glycolipids and glycoproteins and function in cell-cell recognition |
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Term
| Two types of membrane patches in the fluid mosaic model |
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Definition
| Caveolae and lipid rafts are types of these |
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Term
| Lipid rafts are enriched in these |
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Definition
| Cholesterol and Sphingomyelin make these less fluid |
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Term
| Caveolae can serve as a path for these |
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Definition
| Pathogens can enter the host cell through these |
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Term
| These are lipid components of the extracellular side of the plasma membrane |
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Definition
| Sphingomyelin, glycolipids and PC are found here |
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Term
| These are lipid components of the ctyosolic side of the plasma membrane |
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Definition
| PS, PI and PE are found here |
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Term
| Where cholesterol increases/decreases fluidity under normal conditions |
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Definition
| It increases fluidity within th bilayer and decreases fluidity at the nonpolar heads |
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Term
| Means by which cholesterol maintains membrane fluidity at different temperatures |
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Definition
| It decreases fluidity at high temp and increases fluidity at low temp |
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Term
| These types of fatty acids make the membrane more fluid |
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Definition
| These shorter and unsaturated forms make the membrane more fluid |
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Term
| The two major unsaturated fatty acids found esterified in phospholipids |
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Definition
| Oleic acid, Linoleic acid and Arachadonic acid are this type of fatty acids |
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Term
| The fluidity of the plasma membrane is dependent on this |
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Definition
| The fatty acid composition/pattern found in phospholipids helps determine this |
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Term
| These types of molecules can diffuse to through the lipid bilayer |
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Definition
| Gases, hydrophobic molecules and small moleculs can diffuse through this |
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Term
| Passive transport through a protein can be done in both directions and is dependent on this characteristic |
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Definition
| This type of tranport is dependent upon the concentration gradient |
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Term
| Describe the family of GLUT proteins |
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Definition
| They have 12 transmembrane alpha helices and fxn in the facilitated diffusion of glucose |
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Term
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Definition
| RBCs and the brain contain this form of protein transporters for glucose |
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Term
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Definition
| Neurons contain this form of protein transporters for glucose |
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Term
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Definition
| Liver, kidney, Beta pancreatic cells and intestinal mucosal cells toward enterohepatic circulation contain this form of protein transporters for glucose |
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Term
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Definition
| The testes and intestinal mucosal cells towards the lumen contain this form of protein transporters for glucose |
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Term
| GLUT 4 are abundant in these cells |
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Definition
| Fat and muscle cells contain this form of protein transporters for glucose |
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Term
| The function of GLUT 4 is dependent on this |
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Definition
| Insulin is needed by this member of the GLUT family of transporters |
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Term
| The SGLT transport protein |
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Definition
| This transport protein uses the sodium gradient generated by the NA/K ATPase to transport 1 glucose molecue and 2 sodium ions from the intestinal lumen to the intestinal mucosal cells |
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Term
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Definition
| It serves to absorb 1 glucose molecule and two sodium ions from the gut |
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Term
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Definition
| It serves to absorb 1 glucose molecule and two sodium ions from the kidney |
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Term
| The CFTR channel is this type of protein |
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Definition
| It is one example of an ABC-transporter |
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Term
| The mechanism by which the CFTR channel opens |
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Definition
- PKA phosphorylates the regulatory subunit
- Two ATP molecules bind to the ABD sites
- The regulatory subunit drops down from the channel entrance
- ATP gets cleaved to ope the channel
-Chloride ions exit |
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Term
| Components of an ABC transporter |
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Definition
| Their components are two transmembrane alpha-helical domains that form a closed channel. Each domain is connected to an intracellular ATP binding domain and a regulatory domain in front of the channel |
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Term
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Definition
| Salty sweat on the forehead, thick mucus in respiratory and intestine, bilateral absence of vas deferens (males), re-current infections of the lungs and impaired pancreatic function. |
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