Shared Flashcard Set

Details

Terbutaline
drug capsule
11
Pharmacology
Graduate
03/09/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Terbutaline - trade name
Definition
Brethine
Term
Terbutaline - class
Definition

  • β2 agonist
  • synthetic sympathomimetric
  • synthetic catecholamines

Term
Terbutaline - description
Definition

stimulates β2 receptors in smooth muscles of bronchial tree - activates intracellular enzyme adenyl cylase which converts ATP to c-AMP

increases c-AMP levels is assoc. w/ smooth muscle relaxation and inhibition of mediation release from mast cells --> bronchial dilation

Term
Terbutaline - indications
Definition
bronchiospasm
Term
Terbutaline - onset and duration
Definition

onset - within minutes

duration -  4-6 hours

Term
Terbutaline - Contraindications
Definition
hypersensitivity
Term
Terbutaline - adverse reactions
Definition

tachycardia (small amount of β1 effect)

skeletal muscle tremors - inhaled med concentrates in lungs, oral has increased dosage - more likely to cause tremors

Term

Terbutaline - D + A

Adults

Definition

0.25 mg SQ may repeat in 20-30 min

alt. route 1-2 mg in 3 cc NSS nebulized

Term

Terbutaline - D + A

Pediatric

Definition
0.01 mg/kg (max 0.25 cc) SQ - may repeat in 20-30 min
Term
Terbutaline - supply
Definition
ampules 1 mg in 1 ml
Term
Terbutaline - comments
Definition

longer duration than epi wehn given SQ

greater bronchodilation prop.s, less burning pain upon injection, seldom used in older adult patients (>30 y/o)

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