Term
| indication for plavizumab |
|
Definition
| infants <2yo at risk for RSV |
|
|
Term
| indications for ribavirin |
|
Definition
| RSV in infants and children; flu, genital herpes, and llasa fever in adults; hepC when coadministered with IFN-a |
|
|
Term
| AE: respiratory depression in infants |
|
Definition
|
|
Term
|
Definition
|
|
Term
| tx for Aspergillus; AE: visual disturbances |
|
Definition
|
|
Term
| coadministration with quinidine or cisapride is fatal |
|
Definition
|
|
Term
| high CSF therapeutic levels; AE: Steven-Johnson's syndrome, eosinophilia and thrombocytopenia in AIDS pts |
|
Definition
|
|
Term
| flucytosine combinations and indications |
|
Definition
+itraconazole -> chromoblastomycosis
+amphotericin B -> crypto meningitis |
|
|
Term
| indications for caspofungin |
|
Definition
|
|
Term
|
Definition
|
|
Term
tx for coccidiodo meningitis
tx for crypto meningitis
tx for CNS fungal infections, generally |
|
Definition
coccidiodo -> amphotericin B
crypto -> flucytosine+amphotericin B
general -> fluconazole |
|
|
Term
|
Definition
| AE: headache/chills/fever 4h post-infusion, renal toxicity, phlebitis, hypochromic normocytic anemia |
|
|
Term
1. MOA: inhibits beta-1,3 glucase synthase
2 MOA: inhibits lanosterol 14-alpha-demethylase |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| peripheral neuropathy, hepatotoxicity, phentoin toxicity |
|
|
Term
| AE: orange tears, saliva, secretions, etc. |
|
Definition
|
|
Term
| AE: retrobulbar optic neuritis |
|
Definition
|
|
Term
| MOA: active only at acidic pH |
|
Definition
|
|
Term
|
Definition
| nongouty polyarthralgia, uricemia, hepatotoxicity |
|
|
Term
| indicated when there is resistance to other first-line drugs |
|
Definition
|
|
Term
|
Definition
| dapsone, rifampin, clofazimine |
|
|
Term
|
Definition
|
|
Term
| AE: hemolysis in G6P deficient pts |
|
Definition
|
|
Term
| XDR: resistance to what drugs? |
|
Definition
| isoniazid, rifampin, fluoroquinolones, and 1 of 3: amikacin, kanamycin, capreomycin |
|
|
Term
| for extracellular TB only, administered IV |
|
Definition
|
|
Term
1. inhibits mycolic acid synthesis
2. inhibits mycobacterial RNA polymerase
3. inhibits arabinosyl transferase
4. inhibit dihydropteroate synthase
5. inhibits 1,3 glucase synthase
6. inhibits lanosterol 14-alpha-demythlase |
|
Definition
1. isoniazid
2. rifampin
3. ethambutol
4. dapsone
5. caspofungin
6. -azoles |
|
|
Term
| ethionamide can show cross-resistance to... |
|
Definition
|
|
Term
|
Definition
| reddened skin, erythema nodosum |
|
|
