Term
|
Definition
Isoniazid (increases LFTs)
Rifampin (if preexisting condition or if with isoniazid)
Pyrazinamide (liver damage in 15% of patients, with high dose 40mg/kg/d)
Ethioamide |
|
|
Term
|
Definition
|
|
Term
| Liver-->Deacetylation-->Bile |
|
Definition
|
|
Term
| Induces liver enzymes (inc metab of other drugs) |
|
Definition
|
|
Term
| Discolors body fluids or skin |
|
Definition
Rifampin (fluids)
Clofazamine (skin and fluids) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Pyrazinamide (inhibits renal excretion)
Ethambutol (dec uric acid excretion) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Pyrazinamide
Clofazamine (ichthymosis) |
|
|
Term
|
Definition
Ethambutol
Para-amino salicylic acid (bc such a lg dose of acid)
Ethioamide (damages esophagus) |
|
|
Term
|
Definition
|
|
Term
| Inflammation of optic nerves, Loss of visual acuity |
|
Definition
| Ethambutol (so dont use in children!) |
|
|
Term
|
Definition
|
|
Term
|
Definition
Ethioamide
Also, pyrazinamide is not ok for pregnancy |
|
|
Term
|
Definition
Ethambutol (HA)
Ethioamide (HA, depression, tremors, vision, B6 may help)
Cycloserine aka "Psych-serine" (HA, tremor, acute psychosis, hallucinations) |
|
|
Term
|
Definition
| Capreomycin (similar to AG, is a cyclic peptide) |
|
|
Term
|
Definition
| Capreomycin (similar to AG, is a cyclic peptide) |
|
|
Term
| Ichthymosis (dry, itchy, scaly skin) |
|
Definition
|
|
Term
| What are the first line TB drugs? |
|
Definition
Isoniazid
Rifampin, Rifapentine, Rifabutin, (Rifaximin is not for treating TB)
Pyrazinamide
Ethambutol |
|
|
Term
| What are the 2nd line TB drugs? |
|
Definition
Para-amino salicylic acid
Ethionamide
Capreomycin
Clofazamine
Cycloserine |
|
|
