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Systemic pharm II
Drugs to know for final exam
207
Pharmacology
Graduate
11/26/2012

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Term
Methylprednisolone
Definition
Adrenocorticoid
Term
Prednisolone
Definition
Adrenocorticoid
Term
Adefovir
Definition
Anti-viral
For hepatic viral infections
Term
Entecavir
Definition
Anti-viral
For hepatic viral infections
Term
Telbivudine
Definition
Anti-viral
For hepatic viral infections
Term
Tenofovir
Definition
Anti-viral
For hepatic viral infections
Also a nucleoside and nucleotide reverse transcriptase inhibitor
Term
Interferon
Definition
Anti-viral
For hepatic viral infections
ONLY drug that works on Hep C
Also used to treat cancer
Term
Lamivudine
Definition
Anti-viral
For hepatic viral infections
Treatment of HIV
Also a nucleoside and nucleotide reverse transcriptase inhibitor
Does NOT need renal dose adjustment
Does NOT affect mitocondrial DNA
Term
Famciclovir
Definition
Anti-viral
For herpes virus and cytomegalovirus
Term
Foscarnet
Definition
Anti-viral
For herpes virus and cytomegalovirus
Term
Ganciclovir
Definition
Anti-viral
For herpes virus and cytomegalovirus
Term
Penciclovir
Definition
Anti-viral
For herpes virus and cytomegalovirus
Term
Valacyclovir
Also known as Valtrex
Definition
Anti-viral
For herpes virus and cytomegalovirus
Term
Valganciclovir
Definition
Anti-viral
For herpes virus and cytomegalovirus
Term
Vidarabine
Also known as Vira-A
Definition
Anti-viral
For herpes virus and cytomegalovirus
Term
Fomivirsen
Definition
Anti-viral
For herpes virus and cytomegalovirus
Can cause uveitis and vision changes
Term
Acyclovir
Definition
Anti-viral
For herpes virus and cytomegalovirus
Inactive in the uninfected
Term
Cidofovir
Definition
Anti-viral
For herpes virus and cytomegalovirus
Used for CMV retinitis in AIDS patients
Term
Trifluridine
Also known as Viroptic
Definition
Anti-viral
For herpes virus and cytomegalovirus
Very toxic to the cornea
Drug of choice for HSV keratoconjunctivitis and epithelial keratitis
Term
Ribavirin
Definition
Anti-viral
For respiratory infections
Also treats RSV in children and Hep C when added to interferon
Term
Oseltamivir
Also known as Tamiflu
Definition
Anti-viral
For respiratory infections
Neuraminidase inhibitor
Term
Zanamivir
Definition
Anti-viral
For respiratory infections
Neuraminidase inhibitor
Term
Amantadine
Definition
Anti-viral
For respiratory infections
Viral uncoating inhibitor
Derivative of adamantane
Term
Rimantadine
Definition
Anti-viral
For respiratory infections
Viral uncoating inhibitor
Derivative of adamantane
Term
Raltegravir
Definition
Anti-viral
Integrase inhibitor
Term
Amprenavir
Definition
Anti-viral
Protease inhibitor
Term
Atazanavir
Definition
Anti-viral
Protease inhibitor
Term
Darunavir
Definition
Anti-viral
Protease inhibitor
Term
Fosamprenavir
Definition
Anti-viral
Protease inhibitor
Term
Indinavir
Definition
Anti-viral
Protease inhibitor
Term
Lopinavir
Definition
Anti-viral
Protease inhibitor
Term
Saquinavir
Definition
Anti-viral
Protease inhibitor
Term
Ritonavir
Definition
Anti-viral
Protease inhibitor
Enhances other protease inhibitors
Term
Nelfinavir
Definition
Anti-viral
Protease inhibitor
Function is NOT enhanced by ritonavir
Term
Tipranavir
Definition
Anti-viral
Protease inhibitor
Has FDA warnings for hepatitis and intracranial hemorrhages
Term
Enfuvirtide
Definition
Anti-viral
Treatment of HIV
Entry inhibitor
Term
Maraviroc
Definition
Anti-viral
Treatment of HIV
Entry inhibitor
Term
Delavirdine
Definition
Anti-viral
Treatment of HIV
Non-Nucleoside reverse transcriptase inhibitor
Term
Efavirenz
Definition
Anti-viral
Treatment of HIV
Non-Nucleoside reverse transcriptase inhibitor
Term
Etravirine
Definition
Anti-viral
Treatment of HIV
Non-Nucleoside reverse transcriptase inhibitor
Term
Nevirapine
Definition
Anti-viral
Treatment of HIV
Non-Nucleoside reverse transcriptase inhibitor
Term
Didanosine
Definition
Anti-viral
Treatment of HIV
Nucleoside and nucleotide reverse transcriptase inhibitor
Term
Stavudine
Definition
Anti-viral
Treatment of HIV
Nucleoside and nucleotide reverse transcriptase inhibitor
Term
Zidovudine
Definition
Anti-viral
Treatment of HIV
Nucleoside and nucleotide reverse transcriptase inhibitor
Can be used prophylactically for exposed individuals
Term
Emtricitabine
Definition
Anti-viral
Treatment of HIV
Nucleoside and nucleotide reverse transcriptase inhibitor
No significant drug interactions
Term
Abacavir
Definition
Anti-viral
Treatment of HIV
Nucleoside and nucleotide reverse transcriptase inhibitor
Risk of hypersensitivity
Term
Asparaginase
Definition
Anticancer drug
Term
Etoposide
Definition
Anticancer drug
Term
Gefitinib
Definition
Anticancer drug
Term
Imatinib
Definition
Anticancer drug
Term
Irinotecan
Definition
Anticancer drug
Term
Procarbazine
Definition
Anticancer drug
Term
Topotecan
Definition
Anticancer drug
Term
Busulfan
Definition
Anticancer drug
Alkylating agent
Term
Carmustine
Definition
Anticancer drug
Alkylating agent
Term
Chlorambucil
Definition
Anticancer drug
Alkylating agent
Term
Cyclophosphamide
Definition
Anticancer drug
Alkylating agent
Term
Dacarbazine
Definition
Anticancer drug
Alkylating agent
Term
Ifosfamide
Definition
Anticancer drug
Alkylating agent
Term
Lomustine
Definition
Anticancer drug
Alkylating agent
Term
Malphanlan
Definition
Anticancer drug
Alkylating agent
Term
Temozolomide
Definition
Anticancer drug
Alkylating agent
Term
Mechlorethamine
Definition
Anticancer drug
Alkylating agent
Term
Streptozocin
Definition
Anticancer drug
Alkylating agent
Second line TB treatment
Term
Daunorubicin
Definition
Anticancer drug
Antibiotic
Term
Epirubicin
Definition
Anticancer drug
Antibiotic
Term
Idarubicin
Definition
Anticancer drug
Antibiotic
Term
Bleomycin
Definition
Anticancer drug
Antibiotic
Cell-cycle specific
Treats testicular cancer and skin cancer
Term
Doxorubicin
Definition
Anticancer drug
Antibiotic
One of most widely used drugs
May cause red urine and dark red veins
Term
Dactinomycin
Definition
Anticancer drug
Antibiotic
Sensitizes patient to radiation
Term
Capecitabine
Definition
Anticancer drug
Antimetabolite
Term
Cytarabine
Definition
Anticancer drug
Antimetabolite
Term
Gemcitabine
Definition
Anticancer drug
Antimetabolite
Term
6-thioguanine
Definition
Anticancer drug
Antimetabolite
Term
Cladribine
Definition
Anticancer drug
Antimetabolite
Can be used for Multiple sclerosis
Term
Fludarabine
Definition
Anticancer drug
Antimetabolite
Can cause blindness
Term
6-mercaptopurine
Definition
Anticancer drug
Antimetabolite
Maintains remission of acute lymphoblastic leukemia but can be used for Crohn's disease
Term
Methotrexate
Definition
Anticancer drug
Antimetabolite
Part of POMP treatment for leukemia
Can also be used for severe psoriasis, rheumatoid arthritis, and crohn's disease
Folic acid antagonist
Term
5-fluorouracil (5-FU)
Definition
Anticancer drug
Antimetabolite
Used in eye surgery to prevent scarring
Part of FOLFOX treatment for colon cancer
Given with Leucovorin
Term
Vinblastine
Definition
Anticancer drug
Microtuble inhibitor
Term
Vincristine
Definition
Anticancer drug
Microtuble inhibitor
Term
Vinorelbine
Definition
Anticancer drug
Microtuble inhibitor
Term
Docetaxel
Definition
Anticancer drug
Microtuble inhibitor
Doesn't cause nausea/vomiting
Term
Paclitaxel
Definition
Anticancer drug
Microtuble inhibitor
Doesn't cause nausea/vomiting
Term
Cetuximab
Definition
Anticancer drug
Monoclonal antibody
Term
Retuximab
Definition
Anticancer drug
Monoclonal antibody
Term
Trastuzumab
Definition
Anticancer drug
Monoclonal antibody
Term
Bevacizumab
Also known as Avastin
Definition
Anticancer drug
Monoclonal antibody
Used for retinal neovascular disease
Term
Carboplatin
Definition
Anticancer drug
Platinum coordination complex
Term
Cisplatin
Definition
Anticancer drug
Platinum coordination complex
Term
Oxaliplatin
Definition
Anticancer drug
Platinum coordination complex
Part of FOLFOX treatment for colon cancer
Term
Bicalutamide
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Estrogens
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Exemestane
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Flutamide
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Goserelin
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Leuprolide
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Megestrol acetate
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Nilutamide
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Toremifene
Definition
Anticancer drug
Steroid hormone/antagonist
Term
Prednisone
Definition
Anticancer drug
Steroid hormone/antagonist
Adrenocorticoid
Part of POMP treatment for leukemia
Causes increased IOP and cataracts
Term
Aminoglutethimide
Definition
Anticancer drug
Steroid hormone/antagonist
Aromatase inhibitor
Term
Anastrozole
Definition
Anticancer drug
Steroid hormone/antagonist
Aromatase inhibitor
Term
Letrozole
Definition
Anticancer drug
Steroid hormone/antagonist
Aromatase inhibitor
Term
Tamoxifen
Definition
Anticancer drug
Steroid hormone/antagonist
Competes with estrogen so given with leuprolide
Can cause crystalline retinopathy
Term
Artemisinin
Definition
Antiprotozoal
Anti-malarial
Term
Pyrimethamine
Definition
Antiprotozoal
Anti-malarial
Also used for toxoplasmosis when combined with a sulfonamide
Term
Quinine/Quinidine
Definition
Antiprotozoal
Anti-malarial
Causes cinchonism
Term
Primaquine
Definition
Antiprotozoal
Anti-malarial
ONLY agent that kills liver forms after blood forms are eliminated
NOT effective against erythrocytic form
Term
Mefloquine
Definition
Antiprotozoal
Anti-malarial
Safe in pregnancy
Term
Iodoquinol
Definition
Antiprotozoal
Luminal amebicide
Term
Paromomycin
Definition
Antiprotozoal
Luminal amebicide
Term
Metronidazole
Definition
Antiprotozoal
Mixed amebicide
Also used for giardiasis
Term
Tinidazole
Definition
Antiprotozoal
Mixed amebicide
Also used for giardiasis (1 dose)
Term
Dehydroemetine
Definition
Antiprotozoal
Systemic amebicide
Term
Emetine
Definition
Antiprotozoal
Systemic amebicide
Term
Chloroquine
Also known as hydroxychloroquine or Plaquenil
Definition
Antiprotozoal
Systemic amebicide
Also used to treat malaria and arthritis/lupus
Causes bulls-eye maculopathy
Safe in pregnancy
Term
Sodium stibogluconate
Definition
Antiprotozoal
Treats leishmaniasis
Not effective in vitro
Term
Suramin
Definition
Antiprotozoal
Trypanosomiasis treatment
Term
Pentamidine
Definition
Antiprotozoal
Trypanosomiasis treatment
Can be used for pneumocystis jiroveci
Term
Melarsoprol
Definition
Antiprotozoal
Trypanosomiasis treatment
Contraindicated in patients with the flu
Term
Nifurtimox
Definition
Antiprotozoal
Trypanosomiasis treatment
ONLY used for acute Chagas disease
Term
Benznidazole
Definition
Antiprotozoal
Trypanosomiasis treatment
Used prophylactically in stem cell transplants
Term
Nitazoxanide
Definition
Antiprotozoal
Used for giardiasis
Term
Ciclopirox
Definition
Cutaneous antifungal
Term
Nystatin
Definition
Cutaneous antifungal
Antibiotic used only for candida infections because it is toxic
Term
Clotrimazole
Also known as Lotrimin AF
Definition
Cutaneous antifungal
Imidazole
Term
Econazole
Definition
Cutaneous antifungal
Imidazole
Term
Oxiconazole
Definition
Cutaneous antifungal
Imidazole
Term
Sertaconazole
Definition
Cutaneous antifungal
Imidazole
Term
Sulconazole
Definition
Cutaneous antifungal
Imidazole
Term
Terconazole
Definition
Cutaneous antifungal
Imidazole
Term
Tioconazole
Definition
Cutaneous antifungal
Imidazole
Term
Miconazole
Also known as Monistat
Definition
Cutaneous antifungal
Imidazole
Potent warfarin metabolism inhibitor
Term
Tolnaftate
Definition
Cutaneous antifungal
Narrow spectrum, ineffective against candida
Term
Butenafine
Also known as Lotrimin Ultra
Definition
Cutaneous antifungal
Squalene epoxidase inhibitor
Term
Griseofulvin
Definition
Cutaneous antifungal
Squalene epoxidase inhibitor
Term
Naftifine
Definition
Cutaneous antifungal
Squalene epoxidase inhibitor
Term
Terbinafine
Also known as Lamisil
Definition
Cutaneous antifungal
Squalene epoxidase inhibitor
Drug of choice for nail infections
Some visual disturbances reported
Term
Infliximab
Definition
Disease-modifying antirheumatic agent (DMARD)
TNF inhibitor
Term
Cyclizine
Definition
H1 antihistamine
First generation
Term
Diphenhydramine
Also known as benadryl
Definition
H1 antihistamine
First generation
Term
Dimenhydrinate
Also known as dramamine
Definition
H1 antihistamine
First generation
Term
Doxepin
Definition
H1 antihistamine
First generation
Term
Doxylamine
Definition
H1 antihistamine
First generation
Term
Hydroxyzine
Definition
H1 antihistamine
First generation
Term
Promethazine
Also Phenergan
Definition
H1 antihistamine
First generation
Term
Desloratadine
Also known as clarinex
Definition
H1 antihistamine
Second generation, non-sedating
Term
Fexodenadine
Also known as allegra
Definition
H1 antihistamine
Second generation, non-sedating
Term
Loratadine
Also known as Claritin
Definition
H1 antihistamine
Second generation, non-sedating
Term
Acrivastine
Definition
H1 antihistamine
Second generation, weak sedative
Term
Cetirizine
Also known as zyrtec
Definition
H1 antihistamine
Second generation, weak sedative
Term
Antithymocyte globulins
Definition
Immunosuppressant
Antibodies
Term
Muromonab-CD3
Definition
Immunosuppressant
Antibodies
Can cause cytokine storm
Term
Basiliximab
Definition
Immunosuppressant
Antibodies
IL-2 receptor antagonist
Term
Daclizumab
Definition
Immunosuppressant
Antibodies
IL-2 receptor antagonist
Term
Alemtuzumab
Definition
Immunosuppressant
Antibodies
May CAUSE autoimmune disorders
Term
Azathioprine
Definition
Immunosuppressive antimetabolite
Term
Mycophenolate mofetil
Definition
Immunosuppressive antimetabolite
Term
Mycophenolate sodium
Definition
Immunosuppressive antimetabolite
Term
Clofazimine
Definition
Leprosy treatment
Term
Rifampin/riframpicin
Definition
Leprosy treatment
A rifamycin
Makes secretions red/orange colored
Term
Dapsone
Definition
Leprosy treatment
Related to sulfonamides
Term
Almotriptan
Definition
Migraine treatment
Term
Sumatriptan
Definition
Migraine treatment
Term
Etodolac
Definition
NSAID
Acetic acid derivative
Term
Indomethacin
Definition
NSAID
Acetic acid derivative
Term
Celecoxib
Also known as celebrex
Definition
NSAID
Doesn't decrease bleeding time
Cox-2 selective
Term
Diclofenac
Also known as Voltaren
Definition
NSAID
Heteroaryl acetic acid
Term
Ketorolac
Also known as Acular, acuvail, toradol
Definition
NSAID
Heteroaryl acetic acid
Term
Aspirin
Definition
NSAID
Irreversible
Can cause Reye syndrome
Term
Meloxicam
Definition
NSAID
Oxicam derivative
Cox-2 preferential
Term
Ibuprofen
Also known as Advil, Motrin
Definition
NSAID
Propionic acid derivative
Term
Ketoprofen
Definition
NSAID
Propionic acid derivative
Term
Naproxen
Also known as Aleve
Definition
NSAID
Propionic acid derivative
Term
Acetaminophen
Also known as Tylenol
Definition
Other analgesic
Term
Latanoprost
Also known as xalatan
Definition
Prostaglandin analog
Term
Travaprost
Also know as Travatan Z
Definition
Prostaglandin analog
Term
Bimatoprost
Also known as lumigan or latisse
Definition
Prostaglandin analog
Term
Misoprostol
Definition
Prostaglandin analog
Contraindicated in pregnancy
Used to treat NSAID induced ulcers
Also an autacoid
Term
Rifabutin
Definition
Rifamycin
Can cause uveitis
Term
Rifapentine
Definition
Rifamycin
Cannot be used alone
Term
Everolimus
Definition
Selective inhibitor of cytokine production/function
Term
Sirolimus
Also known as rapamycin
Definition
Selective inhibitor of cytokine production/function
Does NOT lower IL-2 levels
Term
Tacrolimus
Definition
Selective inhibitor of cytokine production/function
May cause diabetes to develop
Term
Cyclosporine
Also known as Restasis
Definition
Selective inhibitor of cytokine production/function
Prevents organ rejection, rheumatoid arthritis and dry eye
Term
Fluconazole
Definition
Subcutaneous and systemic antifungal
Term
Flucytosine
Definition
Subcutaneous and systemic antifungal
Term
Amphotericin B
Definition
Subcutaneous and systemic antifungal
A macrolide antibiotic
Drug of choice of life threatening
Term
Anidulafungin
Definition
Subcutaneous and systemic antifungal
An echinocandin
Term
Caspofungin
Definition
Subcutaneous and systemic antifungal
An echinocandin
Term
Micafungin
Definition
Subcutaneous and systemic antifungal
An echinocandin
Term
Itraconazole
Definition
Subcutaneous and systemic antifungal
Drug of choice for histoplasmosis
Term
Voriconazole
Definition
Subcutaneous and systemic antifungal
High bioavailability
Term
Ketoconazole
Definition
Subcutaneous and systemic antifungal
Imidazole
Also inhibits gonadal and adrenal steroid synthesis
Term
Posaconazole
Definition
Subcutaneous and systemic antifungal
Must be given with a high fat meal
Term
Aminoglycosides
Definition
TB treatment
Term
Aminosalicylic acid
Definition
TB treatment
Term
Capreomycin
Definition
TB treatment
Term
Cycloserine
Definition
TB treatment
Term
Fluoroquinolones
Definition
TB treatment
Term
Macrolides
Definition
TB treatment
Term
Pyrazinamide
Definition
TB treatment
1st line treatment
Term
Rifamycins
Definition
TB treatment
1st line treatment
Term
Isoniazid
Definition
TB treatment
1st line treatment
Can cause nystagmus and optic neuritis
Term
Ethambutol
Definition
TB treatment
1st line treatment
Can cause optic neuritis
Term
Ethionamide
Definition
TB treatment
Can cause optic neuritis
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