Term
| what suspends the breast on the chest wall |
|
Definition
|
|
Term
| where does venous drainage occur |
|
Definition
| via axillary, subclavian & intercostal veins |
|
|
Term
| where does lymph drainage from the breast go |
|
Definition
|
|
Term
| how does lymph drainage flow |
|
Definition
|
|
Term
| lowest node draining the cancer |
|
Definition
|
|
Term
| what causes proliferation of the ductal system |
|
Definition
|
|
Term
| in post menopause what is the breast parenchyma replaced by |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| what are the benign breast lesions |
|
Definition
-simple cysts
-fibroadenomas
-papillomas
-fibrocystic diseas
-galactocele
-breast abscess/mastitis |
|
|
Term
| premenstrual cyclic breast pain, tenderness, nodularity are all characteristics of |
|
Definition
|
|
Term
| on mammo: bilateral symmetric diffuse OR focal radiologically dense tissue |
|
Definition
|
|
Term
| normal ovarian hormones produce |
|
Definition
|
|
Term
| noncyclical mastalgia is more likely to be the result of |
|
Definition
|
|
Term
| marker of increasing risk of developing ductal OR lobular carcinoma |
|
Definition
| lobular carcinoma in situ |
|
|
Term
| pre-invasive form of ductal cancer |
|
Definition
|
|
Term
| 90% of the invasive breast cancer |
|
Definition
| infiltrating ductal carcinoma |
|
|
Term
|
Definition
|
|
Term
| what do inflammatory carcinomas present with |
|
Definition
|
|
Term
| what are the RF's for malignant disease |
|
Definition
-increasing age
-+ fhx of breast/ovarian cancer
-HRT
-alcohol
-early menarche
-late menopause
-nulliparity
-radiation exposure |
|
|
Term
| most sensitive & specific imaging test currently available |
|
Definition
|
|
Term
| what are the diagnostic modalities for breast cancer |
|
Definition
|
|
Term
| not for screening, but to evaluate a breast mass |
|
Definition
|
|
Term
| used for imaging internal mammary nodes & evaluate the chest/axilla after mastectomy |
|
Definition
|
|
Term
| imaging of choice to evaluate implant rupture, good for dense scar tissue, used for local staging for DCIs & lobular cancer but it's expensive |
|
Definition
|
|
Term
| what are the characteristics of a her-2-neu oncogene |
|
Definition
-poorer prognosis
-response to herceptin
-correlated w/ ovarian cancer as well |
|
|
Term
| what do her-2-neu receptors respond to |
|
Definition
|
|
Term
| how do we tx breast cancer |
|
Definition
-surgery/radiation
-adjuvant therapy to decreased systemic recurrence (chemo)
-get lots of ppl involved |
|
|
Term
| what surgery do we do for DCIS/invasive carcinoma |
|
Definition
|
|
Term
| surgeon removes the entire breast but leaves nodes and pectoralis muscle |
|
Definition
| modified radical mastectomy |
|
|
Term
| most extensive type of mastectomy removing chest wall muscles as well |
|
Definition
|
|
Term
| when is radiation used in breast cancer |
|
Definition
| after lumpectomy to prevent recurrence |
|
|
Term
| what do we use for ER + breast cancer |
|
Definition
|
|
Term
| what do aromatase inhibitors do |
|
Definition
| decrease circulating estrogen |
|
|
Term
| what are some of the complications of surgery in breast cancer |
|
Definition
-lymphedema (axillary node dissection)
-poor cosmetic result
-wound infxn
-seroma/hematoma
-local recurrence |
|
|
Term
| what are the complications for chemo, hormone tx, RT |
|
Definition
-N/V
-leukopenia, thrombocytopenia
-alopeica
-cardiotoxicity
-sepsis
-hemorrhagic cystitis |
|
|
Term
| does a reconstructed breast have natural sensation |
|
Definition
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