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Stuff I Don't Remember from Psychiatry
USMLE Step 1 Psychiatry
65
Medical
Graduate
04/14/2011

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Cards

Term
What is transference and countertransference?
Definition
Transference = pt projects feelings about formative or other impt persons onto physician
Countertransference = Dr projects feelings about formative or other impt persons onto pt
Term
What is displacement?
Definition
Process whereby avoided ideas and feelings are transferred to some neutral person of object. ex hitting a wall when mad
Term
What is fixation?
Definition
Partially remaining at a more childish level of development (vs regression = turning back maturational clock) ex men fixating on sports games
Term
When is projection?
Definition
unacceptable internal impulse is attributed to an external source. ex a man who wants another woman thinks his wife is cheating on him
Term
What is reaction formation?
Definition
Warded-off idea or feeling is replaced by an emphasis on the opposite. ex. pt w/ libidinous thoughts enters a monastery
Term
What is splitting?
Definition
belief that people are either all good or all bad at different times due to intolerance of ambiguity. Seen in borderline personality disorder
Term
What is sublimation?
Definition
Process whereby one replaces an unacceptable wish w/ a course of action that is similar to the wish but does not conflict with one's value system. ex actress uses experience of abuse to enhance her acting
Term
What are the mature ego defenses?
Definition
Mature women wear a SASH: Sublimation, Altruism, Suppression, Humor
Term
What are the effects of infant deprivation? Deprivation for how long can lead to irreversible changes?
Definition
The 4 W's: Weak, Wordless, Wanting (socially) and Wary
Deprived babies say Wah, Wah, Wah, Wah
>6 mos can be irreversible
Term
What are the childhood and early-onset disorders?
Definition
ADHD, COnduct disorder (<18yo), Oppositional defiant disorder (absence of serious violations of social norms), Tourette's (assoc w/ OCD), Separation anxiety disorder
Term
What are the diagnostic criteria for Tourette's? How is it treated?
Definition
Tics that persist for >1yr. Coprolalia only in 20%. Assoc w/ OCD. Onset <18yo
Tx w/ antipsychotics
Term
What is Rett's disorder?
Definition
X linked in GIRLS
Sx's followed by regression characterized by loss of development, MR, loss of verbal abilities, ataxia and sterotyped hand-wringing
Term
What is childhood disintegrative disorder?
Definition
Marked regression in multiple areas of functioning after at least 2 yrs of normal dev. Common onset b/w 3-4yo. BOYS
Term
What is the difference between Autism and Asperger's?
Definition
Asperger's is milder form. All-absorbing interests, reptitive behavior and problems w/ social relationships. Unlike autism have normal intelligence and lack verbal or cognitive deficits. NO language impairment
Term
What are the neurotransmitter changes associated with Anxiety, Depression, Alzheimer's, Huntington's, Schizophrenia, and Parkinson's?
Definition
Anxiety = increased NE, decreased GABA and serotonin
Depression = decreased NE, serotonin and Dopamine
Alz = decreased ACh
Huntington's = decreased GABA and ACh
Schizo = increased dopamine
Parkinson's = decreased dopamine, increased serotonin and increased ACh
Term
How is delirium different from dementia?
Definition
Delirium is assoc w/ a disease and is a waxing and waning level of consciousness w/ acute onset. Decreased attention span and arousal. Abnormal EEG. REVERSIBLE (dementia isn't usually) Dementia is decreased cognition but no change in consciousness w/ nl EEG.
Term
What are hallucinations vs illusions vs delusions?
Definition
Hallucinations = perceptions in the absence of external stimuli
Illusions = misinterpretations of actual external stimuli
Delusions = false beliefs not shared w/ other members of culture that are firmly maintained in spite of obvious proof to the contrary.
Term
Hypnagogic vs/ hypopompic hallucinations
Definition
HypnaGOgic = while GOing to sleep
HypnoPOMPic = while waking (POMPous upon awakening)
Term
What is the diagnostic criteria for Schizophrenia?
Definition
2 or more of symptoms: delusions, hallucinations, disorganized speech, disorganized or catatonic behavior, "Negative sx's" (flat affect, social withdrawal,lack of motivation, lack of speech or thought.
Term
What are the 5 subtypes of schizophrenia?
Definition
Paranoid, disorganized, catatonic, undifferentiated, residual
Term
What is the greater cause of schizophrenia, genetic or environment?
Definition
Genetic
Term
What is difference b/w schizophrenia, brief psychotic disorder, schizophreniform disorder, and schizoaffective disorder?
Definition
Schizophrenia = >6mos
Brief psychotic dx = <1mo
Schizophreniform = 1-6mo
Schizoaffective disorder = at least 2 weeks of stable mood w/ psychotic sx's + major depressive, manic or mixed episode. (bipolar or depressive)
Term
What is delusional disorder?
Definition
Fixed, persistent nonbizarre belief system lasting >1mo. Functioning not otherwise impaired.
Can be shared (folie a deux)
Term
What are the dissociative disorders?
Definition
Dissociative identity (multiple personality) assoc w/ hx of sexual abuse
Depersonalization dx = feelings of detachment from one's body, situation or environment.
Dissociative Fuge = abrupt change in geographic location w/ inability to recall past, confusion about personal identity or assumption of new identity.
Term
What defines a manic episode?
Definition
at least 1 week
3+ of DIG FAST:
Distractibility, Irresponsibility, Grandiosity, Flight of ideas, increased Activity/Agitation, decreased Sleep, Talkativeness
Term
What is bipolar disorder?
Definition
at least 1 manic/hypomanic episode and depressive symptoms always occur eventually.
Tx w/ mood stabilizers or atypical antipsychotics
Term
What is cyclothymic disorder?
Definition
dysthymia and hypomania; milder form of bipolar that lasts at least 2 years
Term
What are the diagnostic criteria for major depressive episode?
Definition
Lasts 6-12 months. W/ at least 5/9 for 2+ weeks of SIG E CAPS
Major depressive disorder = 2+ major depressive episodes w/ a symptoms-free interval or 2 months
Term
What is dysthymia?
Definition
milder form of depression lasting at least 2 years
Term
What is atypical depression?
Definition
Hypersomnia, overeating and mood reactivity (ability to experience improved mood w/ positive events). Assoc w/ wt gain and sensitivity to rejection.
Tx w/ MAOi's and SSRIs
Term
What are the different postpartum mood disturbances?
Definition
Maternal (postpartum) blues = resolves w/in 10 days (tx supportively)
Postpartum depression = 2weeks-2months (tx w/ antidepressants or psychotherapy)
Postpartum psychosis = delusions, confusions, unusual behavior and homi/suicidal attempts. days to 4-6weeks. Tx w/ antipsychotics, antidepressants, inpt hospitalization
Term
What defines panic disorder? How is it treated?
Definition
PANICS peaking w/in 10mins: Palpitations, Paresthesias, Abdominal distress, Nausea, Intense fear of dying/losing control, lIght-headedless, Chest pain, Chills, Choking, disConnectedness, Sweating, Shaking, SOB.
Tx w/ CBT, SSRIs, TCAs, benzos
Term
How is social phobia treated?
Definition
SSRIs
Term
How is OCD treated? What other disease is it most associated with?
Definition
Assoc w/ Tourette's
Tx w/ SSRIs, clomipramine (TCA)
Term
How is PTSD diagnosed? Treated? How is acute stress disorder different?
Definition
Lasting >1mo
Tx w/ psychotherapy, SSRIs
Acute stress disorder last 2 days-1mo
Term
How long must generalized anxiety disorder be present to be diagnosed?
Definition
at least 6 months
Tx w/ benzos, buspirone (stims 5-HT rec), SSRIs
Term
How is adjustment disorder different from generalized anxiety disorder?
Definition
Adjustment has identifiable psychosocial stressor and lasts <6mo (>6mos chronic stressor)
Term
What is the difference b/w malingering and factitious disorder?
Definition
Malingering = attaining a secondary gain
Factitious dx = primary gain is medical tx
Term
What are the different somatoform disorders?
Definition
Somatization disorder = multiple organ systems (at least 4 pain, 2 GI, 1 sexual and 1 pseudoneurologic) over yrs Conversion = loss of sensory or motor fxn following acute stressor (1 symptom) Hypochondriasis Body Dysmorphic dx Pain disorder = prolonged pain w/ no physical finding
Term
What are the Cluster A Personality disorders?
Definition
Odd or eccentric, assoc w/ schizophrenia
Paranoid
Schizoid = voluntary social withdrawal and content
Schizotypal = odd beliefs + magical thinking
Term
What are the Cluster B Personality Disorders?
Definition
Dramatic, emotional, erratic (assoc w/ mood disorders and substance abuse)
Antisocial (conduct dx if <18, M>F) --> Antisocial = sociopath
Borderline = unstable mood, impulsive, self-mutilations (F>M)
Histrionic
Narcissistic
Term
What are the cluster C personality disorders?
Definition
Anxious or fearful, assoc w/ anxiety
Avoidant = feeling of inadequacy in relationships (vs schizoid = doesn't care)
Obsessive-Compulsive
Dependent
Term
What lab test can be done to test alcohol use. What is treatment for intox?
Definition
Serum gamma-glutamyltransferase (GGT)
AST twice ALT
Tx is naltrexone
Term
What are the signs of alcohol withdrawal?
Definition
severe = delirium tremens (potentially fatal)
Tx = benzos
Term
What are the signs of opioid withdrawal? What is the treatment for withdrawal and intox?
Definition
Dilated pupils, piloerection, flulike sx's
Tx withdrawal symptomatically
Tx intox w/ naloxone/naltrexone
Term
What are the major risks of barbiturate OD and withdrawal?
Definition
OD = marked respiratory depression
Withdrawal = cardiovascular collapse
Term
What can be used to treat benzo OD?
Definition
Flumazenil
Term
What are the symptoms of cocaine intoxication? What can treat it?
Definition
impaired judgement, pupillary dilation, hallucinations, paranoid ideations, angina, sudden cardiac death.
Tx w/ benzos
Term
What are the signs of PCP intoxications?
Definition
Belligerence, impulsiveness, fever, psychomotor agitation, vertical and horizontal nystagmus, tachycardia, homicidality, psychosis, delirium
Term
What are the signs of LSD intoxication?
Definition
Marked anxiety/depression, delusions, visual hallucinations, flashbacks, pupillary dilation
Term
What can be used to treat heroin addiction?
Definition
Naloxone + buprenorphine (partial agonist) = long acting w/ fewer w/d sx's than methadone. Naloxone works if injected (so dissuades IV injection)
Term
What are the major side effects of Chlorpromazine and Thioridazine (typical antipsychotics)?
Definition
Chlorpromazine = Corneal deposits
Thioridazine = Retinal deposits
Term
What are the typical antipsychotics?
Definition
Haloperidol + the -azines
Block D2 receptors
Term
What are the typical antipsychotics and what do they do?
Definition
It's ATYPICAL for OLd CLOSets to QUIETly RISPER from A to Z
Olanzapine, clozapine, quetiapine, reiperidone, aripiprazole, ziprasidone
Block 5-HT, dopamine, alpha and H1 receptors
Term
What atypical antipsychotic has the biggest side effect?
Definition
Clozapine = agranulocytosis
Term
What are the toxicities of Lithium?
Definition
Hypothyroidism, nephrogenic DI, teratogen (ebstein anomaly and malformation fo great vessels), tremor
Term
What does buspirone do?
Definition
Stimulates 5-HT receptors
For anxiety
No dependence but delayed clinical response (2 weeks)
Term
What do TCAs do?
Definition
Block reuptake of NE and serotonin
SE's = Convulsions, Coma, Cardiotox
-pramines, nortriptyline, doxepin and amoxapine
Term
What are the SSRIs? Side effects?
Definition
Fluoxetine, paroxetine, sertraline, citalopram
Sexual dysfunction, Serotonin syndrome (hyperthermia, mm rigidity, cardiovasc collapse, flushing, diarrhea, seizures
Tx serotonin sx w/ CYPROHEPTADINE
Term
What are the SNRIs?
Definition
Venlafaxine, duloxetine
Term
What are the MAOi's? Major side effect?
Definition
Phenelzine, tranylcypromine, isocarboxazid, selegiline
SE = hypertensive crisis w/ tyramine ingestion (cheese, sausage, wine), sexual dysfunction
Term
What does bupropion do? What is it used for?
Definition
Smoking cessation and atypical antidepressant
Increases NE and dopamine (unk mechanism)
NO SEXUAL SIDE EFFECTS
Term
What does Mirtazapine do?
Definition
alpha-2 antagonist (increased release of NE and serotonin)
Term
What does Maprotiline do?
Definition
Blocks NE reuptake
Term
What does trazodone do?
Definition
Inhibits serotonin reuptake
Called TrazoBONE --> causes priapism
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