Term
|
Definition
catalase negative
gram positive |
|
|
Term
|
Definition
puss forming
s.pyogenes - group a
can cause strep throat to necrotising facilitis
can produce exotoxins
complete haemolysis - beta |
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|
Term
|
Definition
part of natural gut flora
all group d
no haeolysis - gamma
usually in pairs
can grow in presence of bile salts
responsible for UTI, bacteraemia, endocarditis, meningitis
can form biofilms
multiple virulence factors produce antibiotic resistance, haemolysin and adhesin
VRE - vancomycin resistant enterococci |
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|
Term
|
Definition
found in nasopharynx of carriers
bunched in pairs
thick slimy capsule
no lancefield antigen
partial haemolysis
most common cause of community acquired pneumonia
toxin and surface associated proteins - PLY
has adhesins
has pili
optichin sensitive |
|
|
Term
|
Definition
no lancefiled antigen
low pathogenicity
all haemolysis types
no capsule
primarily in mouth and URT and mainly only cause disease in the immunocompromised
can cause endocarditis if in blood stream |
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Term
|
Definition
Group A strep - s.pyogenes
numerous exotoxins and harmful enzymes
small
slow growing
complete haemolysis - beta
produce super antigens that overly activate t cells inducing life threatening levels of cytokine release |
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|
Term
| GAS clinical manifestations |
|
Definition
pyogenic
-pharyngitis
-cellulitis
toxogenic
-TSS
-Scarlet fever
immunologic
-rheumatic fever
acute glomerularnephritis |
|
|
Term
|
Definition
tonsils filter bacteria into nasphayrnx
destruction of bacteria cause inflammation
antibiotics given
surgical removal if chronic
quinsy - spread to surrounding tissue |
|
|
Term
|
Definition
Most often a result of invasive GAS skin infection
could be acquired by hysterectomies, vaginal deliveries, bone pinnings
initial flu like symptoms and nausea
progression to high fever, hypotension and organ failure
treatment
-cephalosporins
-penicillins
-vancomycin |
|
|
Term
| acute glomerularnephritis |
|
Definition
several weeks after GAS infection
sudden oedema, haematuria,proteinuria, hypertension
immune response initiated from primary infection
bacterial components covalently link to immunoglobulins
c3 clumps in kidneys
neutrophils attracted
inflammation
more complexes bc of inflammation |
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