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Step 1 - Biochem - Molecular
Facts that are not diseases from the biochem molecular section of 1st Aid
14
Biochemistry
Professional
04/23/2012

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Cards

Term
What type of RNA is...
most abundant
longest
smallest
Definition
Most abundant: rRNA (r for rampant)
Longest: mRNA (m for massive)
Smallest: tRNA (t for tiny)
Term
What type of RNA is...
most abundant
longest
smallest
Definition
Most abundant: rRNA (r for rampant)
Longest: mRNA (m for massive)
Smallest: tRNA (t for tiny)
Term
What type of RNA is...
most abundant
longest
smallest
Definition
Most abundant: rRNA (r for rampant)
Longest: mRNA (m for massive)
Smallest: tRNA (t for tiny)
Term
What are the start codons?
Definition
AUG
Term
What are the stop codons?
Definition
UAA (U Are Away)
UGA (U Go Away)
UAG (U Are Gone)
Term
Which RNA polymerases make which RNAs?
Definition
RNA pol 1 = rRNA
RNA pol 2 = mRNA
RNA pol 3 = tRNA
Term
alpha-amantin
Definition
inhibits RNA pol II
causes liver failure
from death cap mushrooms
Term
What happens to the lac operon in the presence of...
Lactose
Glucose
Definition
Lactose binds to repressor protein and prevents it from inhibiting operon, thus genes are transcribed

Glucose decreases cAMP and decreases activity of the activate, thus genes are silenced
Term
How do tetracyclines work?
Definition
They bind to the 30S subunit of the ribosome preventing attachment of the tRNA
Term
Which end of the tRNA carries the amino acid?
What are the bases there?
Definition
3' end
CCA
Term
How do aminoglycosides work?
Definition
Bind to 30S subunit and prevent initiation complex formation
Term
How does Chloramphenicol work?
Definition
Inhibits 50S peptidyltransferase (no chain elongation)
Term
How do Macrolides work?
Definition
Block translocation of ribosome
Term
How does Clindamycin work?
Definition
Inhibits peptide bond formation
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