Term
|
Definition
1. Gonorrhea
2. Chlamydia
3. nongonococcal urethritis
4. mucopurulent cervicitis |
|
|
Term
|
Definition
|
|
Term
| gram negative intracellular diplococcus: |
|
Definition
|
|
Term
| location and Sx for gonorrhea in females: |
|
Definition
| endocervical canal, 50% asymptomatic, may have discharge, dysuria, labial/abd pain |
|
|
Term
| major complication of gonorrhea mostly oin women: |
|
Definition
| disseminated gonococcal infection |
|
|
Term
| triad of Sx from disseminated gonococcal infection: |
|
Definition
1. dermatitis
2. polyarthralgia/polyarthritis
3. tenosynovitis |
|
|
Term
|
Definition
| Cefixime or ceftriaxone + Tx for chlamydia of it is not ruled out |
|
|
Term
| Non-gonococcal urethritis = |
|
Definition
chlamydia trachomatis (20-40%)
genital mycoplasms (20-30%) |
|
|
Term
| chlamydia trachomatis Sx: |
|
Definition
| mostly asymptomatic in men and women may be a burning sensation upon urination |
|
|
Term
| which test detects gonorrhea and chlamydia from one swab? |
|
Definition
| nucleic acid hybridization |
|
|
Term
| which test has the best sensitivity and specificity for chlamydia? |
|
Definition
|
|
Term
| which lab is able to detect chlamydia in first voided urine sample? |
|
Definition
| LCR ligase chain reaction |
|
|
Term
|
Definition
| azithromycin or doxycycline |
|
|
Term
| STD in women most commonly affects: |
|
Definition
|
|
Term
| cervicitis is primarily caused by (4) |
|
Definition
1. N. gonorrhea
2. C. trachomatis
3. HSV
4. HPV |
|
|
Term
| gonococcal cervicitis sx: |
|
Definition
1. 50% asymptomatic
2. purulent cervical discharge
3. increased menses
4. dysuria |
|
|
Term
| friable cervix with frank ulcers or necrosis: |
|
Definition
|
|
Term
| 20-70% have normal appearing cervix & nonspecific abd pain, maybe mucopurulent discharge: |
|
Definition
|
|
Term
|
Definition
1. gram stain of endocervical mucus
2. cervical cytology
3. virla culture HSV
4. multinucleated giant cells = HSV |
|
|
Term
|
Definition
|
|
Term
| painful genital ulcer is: |
|
Definition
| HSV or chancroid(Haemophilus ducreyi) |
|
|
Term
| painless genital ulcer is: |
|
Definition
1. syphilis
2. lymphogranuloma venereum
3. granuloma inguinale |
|
|
Term
| most common cause of genital ulcer dz in north america and europe: |
|
Definition
|
|
Term
| patient presents with HSV-2 outbreak and are shown to have a titer: Is this a primary or secondary outbreak? |
|
Definition
| secondary; primary outbreaks will not have an antibody titer yet |
|
|
Term
| what is shown on the Tzank smear in HSV-2? |
|
Definition
| multinucleated giant cells |
|
|
Term
| what is the gold standard dx for HSV-2? |
|
Definition
|
|
Term
| which test can differ btwn HSV 1&2? |
|
Definition
| immunofluorescent staining |
|
|
Term
|
Definition
|
|
Term
| what kind of bacteria is syphilis? |
|
Definition
|
|
Term
| what is the second most common cause of genital ulcer dz? |
|
Definition
|
|
Term
| clinical manifestations of primary syphilis: |
|
Definition
1. Solitary painless chancre
2. regional painless lymphadenopathy |
|
|
Term
| define secondary syphilis: |
|
Definition
| hematogenous dissemination of spirochetes |
|
|
Term
| clinical manifestations of secondary syphilis: |
|
Definition
1. rash (whole body including palms)
2. generalized lymphadenopathy
3. malaise
4. alopecia (hair loss)
5. mucous patches
6. condylomata lata |
|
|
Term
|
Definition
| skin lesion specific to secondary syphilis |
|
|
Term
|
Definition
| RPR - Rapid Plasma Reagin Antibody |
|
|
Term
|
Definition
1. darkfield microscopy
2. serology
3. Microhemagglutination- Treponoma pallidum |
|
|
Term
|
Definition
| benzathine penicillin G or doxycycline |
|
|
Term
|
Definition
| benzathine penicillin G ; 3treatments |
|
|
Term
|
Definition
| aqueous crystaline penicillin G larger dose and IV |
|
|
Term
| how do you monitor neurosyphilis tx? |
|
Definition
| CSF q 6mo; CSF VDRL & protein should decrease, if cell count not down in 6mo then retreat |
|
|
Term
| Haemophilus ducreyi causes: |
|
Definition
|
|
Term
| clinical presentation of chancroid: |
|
Definition
| multiple or single painful lesions w painful lymphadenopathy |
|
|
Term
|
Definition
1. gram stain (school of fish appearance)
2. culture
3. PCR |
|
|
Term
| CDC criteria for dx of chancroid: |
|
Definition
1. >1 painful genital ulcer
2. tender inguinal lymphadenopathy
3. negative syphilis
4. negative HSV |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| gram negative rod STD common in Africa, carribean & SW Asia |
|
Definition
| Haemophilus ducreyi (chancroid) |
|
|
Term
|
Definition
| painless progressive ulcerative lesion without regional lymphadenopathy VERY RARE IN US |
|
|
Term
| key words: beefy red lesion that bleeds on contact |
|
Definition
|
|
Term
|
Definition
| requires direct visualization of the organism in darkfield microscopy. |
|
|
Term
|
Definition
|
|
Term
| lymphogranuloma venereum is caused by: |
|
Definition
| chlamydia trachomatis serotypes L1L2L3 |
|
|
Term
| most common presenting sx for lymphogranuloma venereum: |
|
Definition
| unilateral tender inguinal/femoral lymphadenopathy |
|
|
Term
| lymphogranuloma venereum dx: |
|
Definition
| serology or by eliminating other causes of inguinal adenopathy |
|
|
Term
| lymphogranuloma venereum tx: |
|
Definition
|
|
Term
| which HPV causes anogenital warts? |
|
Definition
|
|
Term
| which HPV causes cervical infection/neoplasm? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
1. visual ID
2. PAP smear
3. cervical bx |
|
|
Term
|
Definition
1. removal of symptomatic warts
2. podofilox solution
3. cryotherapy |
|
|
Term
| when are HPV lesions resistant to therapy? |
|
Definition
1. pregnancy
2. DM
3. smokers
4. immunosupressed patients |
|
|
Term
| what are PAP smears screaning for? |
|
Definition
| HPV DNA; over 99% of cervical cancers have HPV DNA detected in the tumor |
|
|
Term
|
Definition
1. conjunctivitis
2. pain on urination
3. joint pain
Can't see Can't pee Can't climb a tree |
|
|
Term
| recurrent persistent urethritis/cervicitis Tx: |
|
Definition
| metronidazole + Erythromycin |
|
|
Term
| safetypin shaped donovin bodies |
|
Definition
|
|
