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Spinal Cord Anatomy
Dr. Yates Lecture 1/26/11
131
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Graduate
02/04/2011

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Term
A long cylindrical structure that lies within the vertebral canal.
Definition
Spinal Cord
Term
Where is the beginning of the spinal cord located?
Definition
At the foramen magnum
Term
Is the spinal cord continuous with the medulla?
Definition
Yes
Term
Where does the spinal cord end?
Definition
In a conical termination known as the conus medullaris
Term
Does the spinal cord ever occupy the entire length of the vertebral canal?
Definition
Yes, up to the 3rd month of fetal life it does
Term
Why does the spinal cord not always run the entire length of the vertebral column?
Definition
The growth of the vertebral column exceeds the spinal cord
Term
Can you have a vertebral fracture that does not damage the spinal cord?
Definition
Yes
Term
What is the job of the vertebral column? (in relation to the spinal cord)
Definition
To protect the spinal cord
Term
What is one downfall to the vertebral column that is not a problem with the skull.
Definition
It has more flexibility which makes it more susceptible to fractures
Term
At birth, the spinal cord is located at what vertebra?
Definition
L3
Term
In the adult, the end of the spinal cord is located between what vertebrae?
Definition
L1 and L2
Term
Where can you get an epidural or spinal tap.
Definition
L4 or below
Term
Name the 3 meningeal layers of the spinal cord.
Definition
Dura
Arachnoid
Pia
Term
Does the spinal cord contain periosteal dura?
Definition
NO
Term
Does the spinal cord contain meningeal dura?
Definition
Yes
Term
Where does the meningeal dura of the spinal cord run to and from?
Definition
Foramen magnum to S2
Term
What does the dura do after S2?
Definition
It extends along with pia to form the coccygeal ligament
Term
Another term for coccygeal ligament.
Definition
Filum Terminale Externum
Term
Does dura cover spinal nerves and nerve roots?
Definition
Yes
Term
A delicate non-vascular membrane that is adherent with the inner surface of the dura.
Definition
Arachnoid
Term
Closely adherent to the spinal cord and has two specializations int he area of the spinal cord.
Definition
Pia
Term
Name the 2 pia specializations
Definition
Denticulate Ligaments
Filum Terminale (Internum)
Term
The end of the spinal cord
Definition
Conus Medullaris
Term
Long nerve roots extending from the end of the spinal cord
Definition
Cauda Equina
Term
Lateral flattened bands of pia mater which are triangula shaped
Definition
Denticulate Ligaments
Term
Ligaments that arise medially from the surface of the spinal cord midway between dorsal and ventral roots
Definition
Denticulate Ligaments
Term
Firmly attach to the arachnoid and inner surface of the dura
Definition
Denticulate Ligaments
Term
Anchor the spinal cord to the dura and are present throughout the length of the spinal cord
Definition
Denticulate Ligaments
Term
Condensation of pia, extending caudally from the conus medullaris until it penetrates the dural tube at the S2 level.
Definition
Filum Terminale Internum
Term
What is the continuation of the filum terminale known as?
Definition
Coccygeal Ligament
Term
How many pairs of spinal nerves are there?
Definition
31
Term
How are the spinal nerves named?
Definition
According to the intervertebral foramina through which they exit
Term
How many paired spinal nerves are in the cervical region?
Definition
8
Term
How many paired spinal nerves are in the thoracic region?
Definition
12
Term
How many paired spinal nerves are in the lumbar region?
Definition
5
Term
How many paired spinal nerves are in the sacral region?
Definition
5
Term
How many paired spinal nerves are in the coccygeal region?
Definition
1
Term
Each segment contains paired dorsal and ventral roots that merge at some distal point to form what?
Definition
Spinal Nerve
Term
Where do spinal nerve emerge from the spinal canal?
Definition
Intervertebral Foramina
Term
Where does the 1st cervical nerve emerge?
Definition
Between Occiput and C1
Term
From spinal nerve C1-C7, where do the emerge in relation to their vertebrae.
Definition
Above their vertebral level
Term
Spinal nerves C8 and lower emerge where in relation to their vertebrae?
Definition
Below
Term
Where does the spinal cord end?
Definition
L1/L2
Term
Due to the fact that the spinal cord ends around L2, but spinal nerves emerge at respective intervertebral foramina, lower nerve roots are very long and form a structure known as what?
Definition
Cauda Equina
Term
Dorsal root fibers are?
Definition
Sensory
Term
Ventral root fibers are?
Definition
Motor
Term
The butterfly shaped central gray substance is composed of what?
Definition
Collections of cell bodies and their processes
Term
The surrounding mantle of white matter is composed of what?
Definition
Bundles of myelinated fibers that are either ascending or descending
Term
What does white matter contain?
Definition
Axons
Dendrites
Term
In the gray matter, what is the posterior gray horn?
Definition
Dorsal (Sensory)
Term
In the gray matter, what is the anterior gray horn?
Definition
Ventral (motor)
Term
Extends posterolaterally almost to the surface
Definition
Posterior Gray Horn
Term
Extends ventrally but does not reach the surface
Definition
Anterior Gray Horn
Term
In thoracic segments, there is a small pointed thing that is evident near the base of the anterior horn.
Definition
Lateral Horn
Term
What is the lateral horn associated with?
Definition
ANS
Term
What is the lateral horn associated with?
Definition
ANS
Term
Connects the gray substance of the two sides and encompasses the central canal.
Definition
Gray Commissure
Term
The white matter of the spinal cord is divided into what?
Definition
3 funiculi
Term
Name the 3 funiculi
Definition
Posterior
Lateral
Anterior
Term
Lies between the posterior median septum and the posterior horn
Definition
Posterior Funiculus
Term
Lies between the dorsal root entry zone (posterior horn) and the site where the ventral root fibers emerge from the spinal cord.
Definition
Lateral Funiculus
Term
Lies between emerging ventral rootlets and the anterior median fissure.
Definition
Anterior Funiculus
Term
The midline of the spinal cord on the anterior surface.
Definition
Anterior Median Fissure
Term
What does the anterior median fissure contain?
Definition
Anterior Spinal Artery
Term
A less distinct groos in the posterior midline that separates 2 posterior columns
Definition
Posterior Medial Sulcus
Term
What does the posterior median sulcus contain?
Definition
Posterior Spinal Nerve
Term
Divides each posterior funiculus into 2 white columns
Definition
Posterior Intermediate Sulcus
Term
Through what levels do you have a posterior intermediate sulcus?
Definition
C1-T6
Term
What does the posterior intermediate sulcus separate?
Definition
Cuneatus
Gracilis
Term
What does the cuneatus and gracilis carry?
Definition
Sensory Information
Term
Which one is more medial? The cuneatus or gracilis?
Definition
Gracilis
Term
An area where the diameter of the spinal cord is larger than the rest
Definition
Enlargement
Term
Consists of the 4 lowest cervical segments and the 1st thoracic segment.
Definition
Cervical enlargement
Term
C5-T1
Definition
Cervical Enlargement
Term
Gives rise to nerve roots that form the brachial plexus
Definition
Cervical Enlargement
Term
Consists of all lumbar and 1st two sacral segments
Definition
Lumbar Enlargement
Term
L1-S2
Definition
Lumbar Enlargement
Term
L1 to L4
Definition
Lumbar Plexus
Term
L4-S2
Definition
Sacral Plexus
Term
Different levels op spinal cord vary in 3 ways:
Definition
1. size and shape
2. relative amounts of gray and white matter
3. disposition and configuration of gray matter
Term
Is the cervical spinal cord large or small
Definition
Large
Term
Is the cervical spinal cord round or oval?
Definition
Oval
Term
Does the cervical spinal cord have lots or not much white matter?
Definition
lots
Term
This means that the transverse diameter exceeds the anterior/posterior diameter at all levels
Definition
Oval Shape
Term
Has a prominent posterior intermediate septum
Definition
Cervical spinal cord
Term
Has an enlarged anterior horn (C5 and below)
Definition
Cervical Spinal Cord
Term
Is the thoracic spinal cord large or small
Definition
Small
Term
Is the thoracic spinal cord round or oval
Definition
Round
Term
This spinal cord segment has a smaller diameter due to marked reduction in gray matter
Definition
Thoracic spinal cord
Term
This spinal cord segment has a posterior intermediate septum T1-T6 but not below
Definition
Thoracic spinal cord
Term
This spinal cord segment has small anterior and posterior horns
Definition
Thoracic spinal cord
Term
Lateral horn containing intermediolateral cell column is present in all levels of the __
Definition
Thoracic Spinal Cord
Term
A rounded collection of large cells at the base of the medial aspect of the posterior horn
Definition
Dorsal Nucleus of Clarke (Nucleus Dorsalis)
Term
Is the nucleus dorsalis present in all thoracic levels?
Definition
Yes
Term
Goes from the spinal cord to the cerebellum known as the Spinocerebellar Tract
Definition
Nucleus Dorsalis
Term
Another term for Lateral Horn
Definition
Intermediolateral cell column
Term
Nearly circular in shape with lots of gray matter
Definition
Lumbar spinal cord
Term
Has massive anterior and posterior horns
Definition
Lumbar spinal cord
Term
Which has less white matter, lumbar or cervical segements?
Definition
Lumbar
Term
This part of the lumbar spinal cord has a lateral horn and the nucleus dorsalis
Definition
L1 and L2
Term
Small in diameter with large amounts of gray matter
Definition
Sacral spinal cord
Term
Has a thin layer of white matter and short, thick gray commissure
Definition
Sacral spinal cord
Term
Has large anterior and posterior horn
Definition
Sacral spinal cord
Term
Area in the center where things can cross over
Definition
Commissure
Term
Another name for Lamina I
Definition
Marginal layer
Term
Another name for Lamina II
Definition
Substantia Gelatinosa
Term
Another name for Lamina VII
Definition
Zona Intermedia
Term
2 other terms for motor neuron
Definition
Alpha Motor Neuron
Anterior Horn cell
Term
Caps the surface of the posterior horn, contains small and medium sized cells which respond specifically to noxious and thermal stimulia
Definition
Lamina I (Marginal layer)
Term
Carries sensory information about pain and temperature and is associated with the anterolateral system
Definition
Lamina I
Term
Corresponds to neurons which can modulate or modify sensory input, particularly pain perception
Definition
Lamina II (Substantia Gelatinosa)
Term
Lies between the anterior and posterior horns
Definition
Lamina VII (Zona Intermedia)
Term
2 things included in Lamina VII
Definition
Nucleus Dorsalis
lateral horn
Term
Located in the medial aspect of Lamina VII from T1-L2
Definition
Nucleus Dorsalis
Term
Cells from this give rise to the posterior spinocerebellar tract
Definition
Dorsal Nucleus of Clarke
Term
Found in the lateral aspect of Lamina VII from T1 to L2. Contains preganglionic sympathetic cells of the ANS
Definition
Lateral Horn
Term
Contains large somatic motor neurons that innervate striated muscle known as alpha motor neurons
Definition
Lamina IX
Term
Scattered among alpha motor neurons are smaller gamma motor neurons that innervate contractile elements of sensory organ known as what?
Definition
Muscle Spindle
Term
Organized according to function
Definition
Anterior horn cells
Term
Medial cells innervate what?
Definition
Axial muscles
Term
Lateral cells innervate what?
Definition
Distal (limb) muscles
Term
Dorsal cells innervate what?
Definition
Flexor muscles
Term
Ventral cells innervate what?
Definition
Extensor Muscles
Term
A complete separation of spinal cord tissue. No connection
Definition
Complete injury in animals
Term
Does not have to be a complete physical tear. Means that there is no function (motor or sensory) at any level in an area and below.
Definition
Complete injury in humans
Term
Means there can either be some sensory or some motor function left
Definition
Incomplete injury
Term
Made from astrocytes. Prevents CNS from having a huge amount of recovery.
Definition
Glial Scarring
Term
Receives sensory input from the periphery and brain
Definition
CPGs (Central Pattern Generators)
Term
Functionally organized neuronal networks in the spinal cord capable of generating a rhythmic pattern of motor activity in the absence of sensory input.
Definition
CPGs
Term
Used in human subjects to support up to 40% of their body weight during locomotion on a moving treadmill
Definition
BWSTT (Body Weight Supported Treadmill Training)
Term
Improves elements of locomotion but not voluntary motor activity in patients with a complete spinal cord injury
Definition
BWSTT
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