Term
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Definition
Smallpox (eradicated)
Vaccinia used as vaccine |
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Term
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Definition
orally transmitted
primary infection: multiple skin/mucous membrane sores
latent in neurons
secondary infection: single, localized sore
Acyclovir! |
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Term
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Definition
Small, scattered pox-like lesions
Latent in nerves
Reactivates to cause shingles
Acyclovir! |
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Term
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Definition
Birth defects with congenital transmission
Mild in healthy individuals
More severe with anemic disorders
Remains latent in Tcells and MQs
Gancyclovir! |
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Term
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Definition
| Abrupt high fever followed by disseminated rash (Roseola) |
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Term
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Definition
Most common cause of Mononucleosis (lymph node enlargement, splenomegaly, etc)
Latent in B-cells
Can cause Burkitt's Lymphoma (EBNA-2 stimulates B cell proliferation, EBNA-3 inactivates Rb) |
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Term
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Definition
Erythema Infectiosum: "face-slap syndrome"
maculopapular rash starting on cheeks
Hb drop (dangerous in anemic disorders) |
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Term
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Definition
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Term
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Definition
cervical squamous cell carcinoma
E6 binds p53
E7 binds pRb
Gardasil/Cervarix vaccine |
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Term
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Definition
| Mucosal infections: conjunctiva (pink-eye), GI, URI/croup, hemorrhagic cystitis |
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Term
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Definition
| Acute hepatitis: Aches, anorexia, nausea followed by jaundice/liver tenderness (elevated liver enzymes) |
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Term
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Definition
Causes 50% of URIs
Fast onset and clearing (10 days) |
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Term
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Definition
| GI infection with chance of meningitis and other complications |
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Term
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Definition
Primary: Generally asymptomatic gut/oropharanx infection
Secondary replication in 5%: poliomyelitis
~2% non paralytic muscle spasms
<2% paralytic poliomyelitis |
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Term
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Definition
| Hand, Foot, & Mouth disease |
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Term
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Definition
Myocarditis (Type IV hypersensitivity)
Pleurodynia (pain with breathing: "Devil's Grip")
Meningitis |
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Term
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Definition
| highly contagious gastroenteritis (remains contagious after symptom cessation) |
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Term
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Definition
Birth defects with congenital transmission
Maculopapular Rash in children
Arthropathy in Adults |
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Term
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Definition
Causes 10-30% of colds (2nd most common)
New strain causes SARS |
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Term
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Definition
Severe fever with joint/muscle pain, risk of hemorrhage, rash
Following mosquito bite (primary host jungle primates)
Vaccine increases uptake into MQs
Secondary infections after survival in MQs |
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Term
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Definition
| Severe fever with risk of encephalitis following mosquito bite (primary host birds) |
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Term
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Definition
Mainly causes chronic hepatitis (70% of the time).
Or rapid cirrhosis (15%) or acute (15%)
Risk of PHC (primary hepatocellular carcinoma) (4%) |
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Term
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Definition
| Most common cause of diarrhea in children |
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Term
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Definition
Resides in T-cells
can cause ATLL (adult T-cell lymphocytic leukemia) 30 yrs
Sexual transmission/blood/breast milk |
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Term
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Definition
Infects MQs (R5) and CD4+ T-cells (X4-higher long term)
Long latency following high viral load during acute phase.
AIDS when CD4 count <200 (weight loss, opportunistic infections and tumors without immune response, dementia) |
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Term
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Definition
URI/croup
Most common cause of vaccine preventable death |
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Term
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Definition
Maculopapular rash (Rubeola) post auricular/forehead to whole body. Koplik's spots on buccal muscosa.
Numerous possible complications. |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| URI. spreads cell to cell via syncitia |
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Term
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Definition
Hemorragic Fever
possible Pulmonary involvement |
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Term
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Definition
severe hemorrhagic fever (bleed from mucous membranes)
maculopapular rash on trunk |
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Term
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Definition
| aseptic meningitis (from rodents) |
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Term
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Definition
Fever like symptoms following animal bite with itching
Followed by neurological symptoms: seizure, paralysis, hallucination. respiratory failure
Treat with immediate vaccination and Ig |
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Term
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Definition
sexually transmitted
primary infection: multiple skin/mucous membrane sores
latent in neurons
secondary infections: single, localized sore
Acyclovir! |
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Term
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Definition
Most prevalent cause of hepatitis.
Chronic (10%) or acute hepatitis. Present in body fluids.
Causes 80% of PHCs (primary hepatocellular carcinomas) |
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Term
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Definition
Benign Genital Warts
Gardasil/Cervarix vaccine |
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Term
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Definition
LRT pneumonia
Can lead to respiratory failure and hypoxemia rapidly
High mortality in elderly |
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