Term
| What protein carries the peptides across the ER membrane to be loaded into grooves of MHC Class I molecules? |
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Definition
| Specific transporter proteins (TAP 1 and TAP2) |
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Term
| What are the proteins up regulated on the surface of macrophage to preferentially chip the proteins that will fit MHC Class I grooves (after hydrophobic or basic amino acids)? |
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Definition
| LMP2, LMP7, MECL1 replace the proteasome proteins that chip the proteins after hydrophobic or basic amino acids because TAP and MHC I favor peptides that have either hydrophobic or basic C termini. |
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Term
| What cells have MHC Class I receptors? |
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Definition
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Term
| What cells have MHC Class II receptors? |
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Definition
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Term
| What cells display MHC class I? |
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Definition
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Term
| What cells display MHC class II? |
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Definition
| APCs/ cells of immune system |
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