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Sompayrac Chapter 2
Sompayrac Chapter 2
10
Immunology
Professional
09/14/2012

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Cards

Term
What enzyme present on the surface of human cells accelerates clipping of the complement fragment C3b?
Definition
MCP
Term
What protein present on the surface of human cells accelerates the destruction of the complement convertase C3bBb?
Definition
DAF- decay accelerating factor
Term
What protein present on the surface of human cells destroys MAC(membrane attack complex)?
Definition
CD59 - Protectin
Term
Name the complement alternative pathway convertase
Definition
C3bBb
Term
Name the lectin complement pathway convertase
Definition
MASP (bound to MBL)
Term
What cytokine does a hyperactivated macrophage produce and secrete?
Definition
Tumor Necrosis factor (TNF)
Term
What cytokine activates a resting macrophage?
Definition
Interferon gamma (IFN -gamma)
Term
What cytokines signal the endothelial cells to express selectins on their surface?
Definition
TNF and IL1
Term
What signals the neutrophil to express more integrins?
Definition
LPS and complement fragment C5a
Term
What chemoattractants help a neutrophil exit the blood vessels and migrate to the site of infection?
Definition
C5a and f- met(formyl methionine)
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