Term
| Vascular malformations classifications |
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Definition
| AVM (ateriovenous malformation), Cutaneous "skin" = port wine stain; relatively common; failure of normal development to get vessels to interact with each other |
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Term
| Etiology of vascular malformations |
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Definition
| Abnormal vascular morphogenesis; no endothelial proliferation (not a neoplasm); types: part of same process - capillary vascular malformation, venous malformation, ateriovenous malformation |
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Term
| Capillary vascular malformations |
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Definition
| Collection of small capillaries |
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Term
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Definition
| Collection of LARGE dilated vascular channels |
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Term
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Definition
| Tangle(s) of vessels w/ abnormal connections; may have arterial-venous connection without intervening capillary bed; really big vessels flow doesn't slow down = high flow area |
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Term
| Clinical features (intra-oral) of vascular malformations |
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Definition
| +/- present at birth, soft tissue, +/- underlying bone (gingiva and underlying alveolar process); persistent with growth (proportional to growth of individual, do not involute) |
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Term
| Radiographic appearance of vascular malformations intrabony lesions |
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Definition
| Appearance variable, often internal trabeculae visible; +/- "sunburst" radiographic appearance (resembling osteosarcoma); CT/MRI +/- angiography/MRA |
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Term
| Significant of intrabony lesions (vascular malformations) |
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Definition
| Needle aspiration of any undiagnosed intrabony lesions prior to Bx to r/o central vascular malformation |
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Term
| Another name for sturge weber syndrome (angiomatosis) |
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Definition
| Encephalotrigeminal angiomatosis |
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Term
| Etiology of Sturge Weber syndrome |
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Definition
| Developmental, non-hereditary, CRITERIA (NB: both required): 1. unilateral port wine stain long skin innervated by 1 or more branches of V1; 2. vascular malformations of leptomeninges |
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Term
| Clinical (extra-oral) sturge weber syndrome |
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Definition
| UNILATERAL port wine stain along distribution of trigeminal nerve (only 10% of people w/ facial port wine stains have SWS, must include V1 involvement); +/- ocular lesions (glaucoma +/1 ocular vascular malformations); vascular malformations of leptomeninges (requires V1 involvement) |
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Term
| Radiology of sturge weber syndrome |
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Definition
| calcification of intracranial vascular malformations = "tramline" calcifications on skull film |
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Term
| Which disorder is associated with unilateral port wine stain? |
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Definition
| Sturge weber syndrome (angiomatosis) |
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Term
| Clinical significance of sturge weber syndrome |
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Definition
| Oral involvement leading to bleeding, bone underneath it, gingival malformations; seizures; reduced mental capacity; contralateral hemiplagia |
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Term
| Syndrome associated with contralateral hemiplagia |
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Definition
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Term
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Definition
| Developmental anomalies of lymphatic vessels; not a neoplasm |
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Term
| Clinical features of lymphangioma |
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Definition
| Congenital (50%); rest by 2nd year; esp head and neck |
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Term
| Intraoral of lymphangioma |
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Definition
| Anterior 2/3s of tongue, macroglossia, superficial lesions (pebbly surface, clear fluid to red "cavier-like"), deeper lesions (soft, ill-defined mass) |
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Term
| Histopathology of lymphangioma |
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Definition
| lymphatic channels (immediately underneath epithelial surface); not a true "neoplasm" |
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Term
| Significance of lymphangioma |
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Definition
| Trauma or infection --> +/- massive engorgement (esp if airway obstructed, no treatment if asymptomatic) |
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Term
| Etiology of cystic hygroma |
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Definition
Type of lymphangioma characterized by large spaces
Esp in neck |
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Term
| Significance of cystic hygroma |
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Definition
| Respiratory difficulty, dysphagia, +/- death (2-5%) |
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Term
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Definition
| Congenital, neoplastic proliferation of endothelial (blood vessel lining cells) |
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Term
| Demographics of hemangioma |
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Definition
- 1.1-2.6% of newborns, 5-10% of 1 year olds
- Growth 1st 8 weeks of life
- 60%
- But can occur anywhere
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Term
| Intra-oral clinical features of hemangioma |
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Definition
| Size range: very small-very large; flat or elevated/nodular; lips, tongue, BM; superficial = red; deep = blue |
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Term
| True or false: most hemangioma involute & resolved by age 9 |
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Definition
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Term
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Definition
| proliferation of endothelial cells |
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Term
| Vascular malformations vs. hemangioma |
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Definition
Differentiating between these on clinical appearance alone often= difficult
Often need Hx +/- Bx
Management suggestions: refer out for Bx |
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Term
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Definition
| Malignant neoplasm of endothelial cells |
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Term
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Definition
| Rare, 50% H&N, early lesions non-specific "bruise", skin, oral mucosa, jaws |
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Term
| Histology of angiosarcoma |
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Definition
| Endothelial cell proliferation, cellular features of malignancy |
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Term
| Etiology of Kaposi's sarcoma |
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Definition
"malignant" proliferation of endothelial +/- lymphatic cells
HHV-8 |
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Term
| 3 types of kaposi's sarcoma |
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Definition
| Classic, endomic, immunodeficiency |
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Term
| Classic type of kaposi's sarcoma |
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Definition
| older mediterranean men; red nodules; skin of extremities; long indolent course |
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Term
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Definition
| african children or adults; skin of extremities; long course; fair prognosis |
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Term
| Immunodeficiency kaposi's sarcoma |
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Definition
| AIDS and transplant patients; younger adults; skin, mucosa, internal organs; multi-focal; aggressive; poor prognosis untreated |
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