Term
| Who is more likely to get SLE? |
|
Definition
| African Americans 4x - women |
|
|
Term
| What is the pathological hallmark of SLE? |
|
Definition
| widespread vascular injury |
|
|
Term
| what antibodies are present in almost all cases of SLE? |
|
Definition
| antinuclear antibodies to dsDNA |
|
|
Term
| what infection should you suspect with SLE? |
|
Definition
|
|
Term
| What as a rule is significant enough to make the diagnosis? |
|
Definition
| characteristic disease of one organ plus high titer of anti-dsDNA or Sm antibody |
|
|
Term
| What are the most common early manifestations of SLE? |
|
Definition
1) arthritis
2) malaise
3) cytopenias
4) rashes |
|
|
Term
| What unique type of cells are seen with lupus? |
|
Definition
| LE cells - RBCs engulfed by WBC |
|
|
Term
| What GI problem is common with long standing SLE? |
|
Definition
|
|
Term
| What hematologic disorder is common with SLE and if not present should question diagnosis? |
|
Definition
|
|
Term
| What is one of the most serious neurological problems associated w/lupus? |
|
Definition
| focal brain disease, myelopathy and peripheral neuropathy |
|
|
Term
| What if found in the urine is characteristic of renal involvement and hypocomplementemia? |
|
Definition
|
|
Term
| What labs, if normal, exclude SLE? |
|
Definition
|
|
Term
| What should all SLE patients have at time of clinic visit? |
|
Definition
|
|
