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SGU Immuno Vocab 1
SGU Immunology vocab 1 Sept 2009
21
International Studies
Graduate
09/19/2009

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Term
ADAPTIVE IMMUNITY
Definition
The part of the immune system that is SPECIFIC and has MEMORY
Term
Antibodies
Definition
Molecules that are secreted by PLASMA CELS. They bind antigen in a SPECIFIC manner
Term
Antigen
Definition
classic definition - molecules that have specific sequences to which adaptive immune responses can be generated
Term
Antigenicity
Definition
A property of molecules to which an adaptive immune response can be generated
Term
Antigenic determinant (epitope)
Definition
A particular component of an antigen that is recognizable by UNIQUE lymphocyte receptors (That component of an antigen that is recognized by B cells or T cells. T cells recognize ONLY antigens displayed with MHC)
Term
Bursa of Fabricius
Definition
Tissue where B cells mature from progenitor cells IN CHICKENS
Term
COMPLEMENT
Definition
Host dfense system consisting of soluble and membrane-bound protiens
Term
Chemokines
Definition
small molecules that were originally identified because of thier role in ATTRACTING CELLS TO A PARTICULAR REGION
Term
CYTOKINES
Definition
Molecules that are secreted primarily (but not exclusively) by cells of the immune system. These play an important role in the ACTIVATION AND DOWN-REGULATION OF THE IMMUNE SYSTEM
Term
DETERMINANT
Definition
See epitope or antigenic determinant
Term
Epitope
Definition
See antigenic determinant/ determinant
Term
FOLLICLE-ASSOCIATED EPITHELIUM
Definition
That region of the lumenal epithelium that is NOT covered by MUCOUS
Term
GERMINAL CENTRE
Definition
That component of a follicle where antigen-induced B cell DIFFERENTIATION occurs
Term
HAPTEN AND CARRIER
Definition
A small molecule (<6kD)that is NOT IMMUNOGENIC UNLESS IT BINDS TO A PROTIEN (carrier). CARRIER is a protien to which the small molecule has bound, permitting an ANTI-HAPTEN IMMUNE RESPONSE
Term
HEMATOPOIESIS
Definition
A term used to refer to the differentiation of various cell types from a pluripotent stem cell. CYTOKINES PLAY AN IMPORTANT PART IN THE PROCESS !
Term
IMMUNOGENICITY
Definition
A term used synonomously wiht the CLASSICAL definition of antigenicity - Refers to a molecule that can serve as a stimulus for an ADAPTIVE immune response
Term
INNATE IMMUNITY
Definition
The component of immunity in which cells and effectors DO NOT HAVE MEMORY, NOR RECEPTORS SPECIFIC FOR AN EPITOPE
Term
Mitogen
Definition
Polyclonal activator - Can activate B cells WITHOUT T CELL HELP !!
Term
PERAIRTERIOLAR LYMPHATIC SHEATH (PALS)
Definition
Region containing the WHITE pulp
Term
White Pulp
Definition
Retion of the SPLEEN within PALS" predominant immune cell is the T CELL and where primary T CELL RESPONSES can occur.
Term
Tolerance (self tolerance)
Definition
The fact that the immune system is NOT pathologically activated in the presence of its own antigens.
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