Term
| What disease is caused by Treponema pallidum? |
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Definition
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Term
| an aerobic spirochete that is a slender spiral with uniform tightly wound coils |
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Definition
|
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Term
| two nonpathogenic strains of Treponema pallidum |
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Definition
| Reiter's strain and Nichol's strain |
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Term
| two treponems that are morphologically identical to Treponema pallidum |
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Definition
| Treponema pertenus and Treponema carateum |
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Term
| what disease is caused by Treponema pertenus? |
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Definition
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Term
| what disease is caused by Treponema carateum? |
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Definition
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Term
| what stage of syphilis infection has a lesion called a chancre? |
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Definition
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Term
| the onset of primary syphilis occurs how long after contact? |
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Definition
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Term
| in primary syphilis, what test is 70-80% positive? |
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Definition
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Term
| in primary syphilis, what test is 85% reactive? |
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Definition
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Term
| what kind of microscopy is used to visualize the spirochete isolated from a chancre? |
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Definition
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Term
| onset of secondary syphilis occurs how long after primary lesion? |
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Definition
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Term
| a cutaneous rash, fever, sore throat, headache, malaise, mucous patches in the mouth are all symptoms of what? |
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Definition
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Term
| during secondary syphilis, what two tests are 100% reactive? |
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Definition
| nontreponema tests and treponemal tests |
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Term
| a noninfectious period following the secondary stage of syphilis which may last from 6 months to 25 years after the inital infection |
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Definition
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Term
| what stage of syphilis has no signs or symptoms? |
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Definition
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Term
| during the latent period, what test is 70% reactive? |
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Definition
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Term
| during the latent period, what test is 97% reactive? |
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Definition
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Term
| during the latent period, can cerebrospinal fluid be used to test for syphilis? |
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Definition
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Term
| how long after infection is the onset of tertiary syphilis? |
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Definition
| 1 1/2 to 25 years or more |
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|
Term
| three general forms of tertiary syphilis |
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Definition
| benign tertiary lesions (gumma), neurosyphilis (8%), cardiovascular syphilis (10%) |
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|
Term
| what percent of patients with untreated latent syphilis will develop tertiary syphilis? |
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Definition
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Term
| what test is 95% reactive in neurosyphilis? |
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Definition
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Term
| in tertiary syphilis, what test is more likely to be reactive when using cerebrospinal fluid? |
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Definition
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Term
| what can cause a baby to be born stillborn, deformed or scarred? |
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Definition
|
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Term
| what drug is used to treat all stages of syphilis? |
|
Definition
| penicillin, tetracycline or doxycycline |
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|
Term
| method of choice for visualizing spirochetes |
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Definition
|
|
Term
| what does FTA-ABS stand for? |
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Definition
| fluorescent treponema antibody absorption test |
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|
Term
| confirmatory method for positive nontreponemal tests |
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Definition
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|
Term
| Five types of treponema tests |
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Definition
| Treponema palidum immobilization test, fluorescent treponema antibody absorption test (FTA-ABS), microhemagglutination assay for treponema pallidum (MHA-TP), Kolmer and Reiter complement fixation test, Treponema hemagglutination inhibition test (TPHI) |
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Term
| which is less technically demanding, FTA-ABS or MHA-TP? |
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Definition
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|
Term
| what is another name for nontreponemal tests? |
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Definition
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Term
| VDRL, RPR and ART are all types of what? |
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Definition
| nontreponemal syphilis tests |
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|
Term
| a variation of RPR, used in large blood centers |
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Definition
| ART- automated reagin test |
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|
Term
| what syphilis test is used to test cerebrospinal fluid? |
|
Definition
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Term
|
Definition
| Epstein-Barr virus, herpes simplex virus, cytomegalovirus, varicella zoster |
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|
Term
| acute, self-limiting lymphoproliferative disease distinguished from lymphoma by tendency to spontaneous regression |
|
Definition
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Term
|
Definition
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|
Term
| fever, malaise, headache, lethargy, sore throat with exudate, splenomegaly and lymphadenopathy are all symptoms of what? |
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Definition
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|
Term
| two possible complications of infectious mononucleosis |
|
Definition
| hepatitis and encephalomeningitis |
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|
Term
| any substance that stimulates the formation of sheep hemolysin |
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Definition
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|
Term
| several groups of antigens that occur in cells or fluid of unrelated animals and microorganisms and are so closely related that they cross-react with antibodies against any one member of the heterophile group |
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Definition
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|
Term
| three ways EBV is transmitted? |
|
Definition
| saliva, blood transfusion, and possibly by mosquitoes |
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|
Term
| what percent of healthy adults have antibodies to EBV? |
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Definition
|
|
Term
| what virus causes Burkitt's lymphoma in East Africa? |
|
Definition
|
|
Term
| what virus causes Nasopharyngeal carcinoma in South China? |
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Definition
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|
Term
| a hemagglutination test for the presence of heterophile antibodies in the blood |
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Definition
|
|
Term
| what test is used to differentiate heterophile antibodies (Forssman, serum sickness, infectious mononucleosis)? |
|
Definition
| Davidsohn Differential test |
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|
Term
| are infectious mono heterophile antibodies absorbed by guinea pig kidney cells? |
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Definition
|
|
Term
| Are Forssman antibodies absorbed by guinea pig kidney cells? |
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Definition
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|
Term
| agglutination after guinea pig kidney absorption indicates presence of what heterophile antibody? |
|
Definition
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|
Term
| agglutination after beef RBC absorption indicates presence of what heterophile antibody? |
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Definition
|
|
Term
| no agglutination after guinea pig kidney absorption and beef RBC absorption indicates presence of what heterophile antibody? |
|
Definition
|
|
Term
| what is the usual method of specific detection of EBV? |
|
Definition
| indirect immunofluorescence |
|
|
Term
| what is the most sensitive indicator of EBV? |
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Definition
|
|
Term
| most severe complication of herpes simplex infection |
|
Definition
| central nervous system involvement |
|
|
Term
| which herpes simplex virus most commonly causes oral lesions? |
|
Definition
|
|
Term
| which herpes simplex virus most commonly causes genital lesions? |
|
Definition
|
|
Term
| which herpes simplex virus may cause encephalitis? |
|
Definition
|
|
Term
| which herpes simplex virus may cause aseptic meningitis? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| most common serological testss for cytomegalovirus |
|
Definition
| ELISA and latex agglutination |
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Term
|
Definition
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|
Term
| causitive agent of chicken pox and shingles |
|
Definition
|
|
Term
| how is varicella zoster virus transmitted? |
|
Definition
| inhalation of infected respiratory droplets or contact with skin lesions |
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