Term
a systemic inflammatory response to a documented or suspected infection |
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Definition
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Term
hypotension unresponsive to fluid resuscitation along with signs of inadequate tissues perfusion |
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Definition
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Term
signs of inadequate tissue perfusion r/t septic shock |
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Definition
metabolic acidosis, acute encephalopathy, oliguria, coagulation disorders |
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Term
septic shock develops when _ release toxic substances that cause blood vessels to _ theryby decreasing vascular resistgance and increasing capillary permeability |
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Definition
pathogenic organisms, dilate |
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Term
lefe threatening organ dysfunciton caused by a dysregulated host response to infection |
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Definition
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Term
pts who have detriorated from a state of speps to septic shock can be identified by having a _ requirement to mainatin a mean arteria pressure of _ or greater and serum lactate level greater than _ in the absence of hypovolemia |
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Definition
vasopressor, 65mmhg, 2mmol/L (>18mg/dL |
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Term
an acid fast aerobic bacterium that causes TB |
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Definition
mycobacterium tuberculosis |
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Term
TBH is spread through droplets emitted during |
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Definition
coughing, laughing, sneezing and singing |
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Term
drug resistant strains of TB include |
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Definition
multidrug resistant TB and extesnsively drug resistant tb |
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Term
those at increased risk for tb include |
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Definition
older adults, the economically disadvataged and holess, those with substance use disorders, children younger than 5 years, people who are immunosuppressed and some racial and thnic groups |
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Term
a patient's initial tb infection is called the |
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Definition
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Term
most people in whom primary infections develop do not acquire |
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Definition
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Term
the infected tb site usually heals creating scare tissue, the lesion is callled a |
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Definition
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Term
tb is primarily an infection of the _ but the organisms may spread and cause infection in the _ |
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Definition
lungs bones, meninges, genitoruinary tract, lymph nodes, pleurae, pericardium, abdomen and endocrine glands |
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Term
, M. tuberculosis infection outside the lungs is called |
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Definition
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Term
s&s of pulmonary tb may include |
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Definition
cough, night sweats, chest pain and tightness, fatigu, anorexia, weightloss, low grade fever |
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Term
cough caused but tb is ofte _ and may produce |
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Definition
persisten and productive, bloody sputum |
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Term
older adults with tb may have only |
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Definition
vague symptoms and fever of undetemrined origin |
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Term
tby should be ocnsidered in patients who have pneumonia that does not: |
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Definition
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Term
the pt is set to have a positive reaction to a tuberculin skin test if a hard area of _ or more develops at the site within |
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Definition
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Term
the gold standard for dianosib TB is culture on _ followed by drug susceptibility testing, this process takes _ wks |
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Definition
solid or liquid media, 2 to 6 |
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Term
blood tests used to diagnosis TB more quickly are |
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Definition
interferon gama release assays(IGRAs) |
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Term
interferon gamma release assays include the |
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Definition
quantiFERON-TBg gold in-tube test, quantiFERON-TB gold test, T-SPOT.TB test |
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Term
Igra results are availiabel in |
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Definition
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Term
IGRA does not distinguish between |
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Definition
active and past TB infections |
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Term
detects m. tuberculosis in respiratory secretions and etermins susceptibility ot rifampin within 2 hours, test is very expensive |
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Definition
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Term
people who have been vaccinated with _ may have a positive response to the tuberculin test even thought they have never had the disease |
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Definition
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Term
patients who have positive results for tb on skin tests and negative results on chest radiographs but who are at increased risk for the disease are usually treated _ to prevent development of active TB |
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Definition
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Term
latent TB is treated with _ alone daily for _ or _ weekly for _ |
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Definition
isoniazid, 9 months, INH with rifapentine, 3 months |
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Term
the 3 month course for treating latent TB must be administered by: |
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Definition
directly obsevered therapy(DOT) |
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Term
for pts with active TB the CDC recommends combintation drug terapy selected from the first lin drugs that include |
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Definition
INH, ehtambutol, rifampin and pyrazinamide |
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Term
an example of an initial regimen for a person with culture positive pulmonary TB is _ given _ |
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Definition
INH, rifampin, pyrazinamide and theambutol daily, twice weekly or 3 times weekly for 2 months |
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Term
after the initial regimen for treating a person with culture positive pulmonary tb caused by drug sensitive organisms the pt would then continue therapy with only |
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Definition
INH and rifampin daily on a daily, twice weekly or thrice weekly schedule |
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Term
neither _ is destroyed by _ |
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Definition
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Term
decreases effective ness of some anti HIV drugs |
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Definition
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Term
DOT is recommended in the case of |
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Definition
pulmonary TB with positive sputum smear, treatment fialure, disease relapse, drug resistance, HIV infection, pyschiatric illness, substance abuse, meory impariment, hx of nonadherance to therapy |
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Term
gowns are unnecessary for TB pt unless |
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Definition
gross contamination of clothing occurs |
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Term
common adverse effects of antitubercular drugs |
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Definition
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Term
measures that may reduce the drug's side effects include |
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Definition
taking it at bed time and taking antinausea drugs |
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