| Term 
 
        | how quickly must shock be treated to increase survival |  | Definition 
 
        | admin fluids >60 mL/Kg within FIRST hour or presentation significantly reduces mortality in peds |  | 
        |  | 
        
        | Term 
 
        | common causes of cardiogenic shock |  | Definition 
 
        | congenital heart dx, recent cardiac surgery, recent viral illness, late septic shock |  | 
        |  | 
        
        | Term 
 
        | early onset empiric neonatal sepsis treatment |  | Definition 
 
        | AMP + aminoglycoside OR 3rd gen Cef (except ceftriaxone--> kernicterus) |  | 
        |  | 
        
        | Term 
 
        | LATE onset empiric neonatal sepsis |  | Definition 
 
        | if discharged, same as home; if hospitalized, Ceftaxime + vanco (staph) OR cefotaxime + aminoglycoside (ecoli, klebsiella,hflu) |  | 
        |  | 
        
        | Term 
 
        | factors affecting treatment of neonatal sepsis |  | Definition 
 
        | alterations in PK/PD within peds, antibiotic spectrum of activity, site infection, pathogen, past ABx history, regional/ institutional resistance, potential toxicities |  | 
        |  | 
        
        | Term 
 
        | venous return is decreased |  | Definition 
 
        | lack of fluid in the vascular space, causing decreased ventricular filling |  | 
        |  | 
        
        | Term 
 
        | ventricals receive less blood |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | compensating for diminished stroke volume and results in poor cardiac output and blood pressure |  | 
        |  | 
        
        | Term 
 
        | fluid and blood loss continues |  | Definition 
 
        | heart rate will not be able to compensate for decreased SV |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | results in inadequate tissue perfusion |  | 
        |  | 
        
        | Term 
 
        | hypovolemia's impact on shock: |  | Definition 
 
        | decreased pre-load and loss of volume (blood/ water loss external/internally) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | primary cause of shock in peds worldwide |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | trauma, vomiting, diarrhea, poor appetite, diabetes |  | 
        |  |