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Sensory Physiology
Matt Hobbs
169
Physiology
Undergraduate 3
10/13/2011

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Term
What are the various forms of sensation as sight, taste, or touch?
Definition
Modalities
Term
Where in the human body does the perception of sensation occur?
Definition
in the brain
Term
What two broad categories may be used to classify sensory receptors?
Definition
function and structure
Term
What functional category of sensory receptors respond to chemical stimuli?
Definition
chemoreceptors
Term
What functional category of sensory receptors respond to light?
Definition
photoreceptors
Term
What functional category of sensory receptors respond to heat and cold?
Definition
thermoreceptors
Term
What functional category of sensory receptors respond to mechanical deformation?
Definition
mechanoreeceptors
Term
What functional category of sensory receptors respond to pain?
Definition
nociceptor
Term
What functional category of sensory receptors respond to body position?
Definition
proprioceptors
Term
What functional category of sensory receptors respond to sensations from the skin?
Definition
cutaneous receptors
Term
What type of receptors respond to continuous stimulus with a burst of activity and then quickly
decrease their firing rate?
Definition
phasic receptors
Term
What type of receptors respond to a continuous stimulus by maintaining their rate of firing as long as
the stimulus continues?
Definition
tonic receptors
Term
What law states that a sensory nerve fiber will produce only one sensation?
Definition
the law of specific nerve energies
Term
What are the depolarizations that are produced by sensory receptors in response to sensory stimuli?
Definition
receptor (generator) potentials
Term
What are the sensations of touch, pressure, heat, cold, and pain in the skin?
Definition
cutaneous sensations
Term
What group of sensations includes those from cutaneous receptors and proprioceptors?
Definition
somatesthetic senses
Term
In what part of the brain are somatesthetic senses perceived?
Definition
the postcentral gyrus of the contralateral side of the brain
Term
What is pain produced by stimulation of one region of the body but which is perceived in a different
area?
Definition
referred pain
Term
What is the area of skin whose stimulation results in changes in the firing rate of the sensory neuron serving that area?
Definition
receptive field
Term
How does the area of receptive fields vary with the density of receptors?
Definition
inversely
Term
What is the minimum distance at which two points of touch can be perceived as separate on the skin?
Definition
two-point touch threshold
Term
What is the sensation of a limbís presence after amputation?
Definition
phantom limb (it often involves pain and is often called phantom pain)
Term
What process sharpens sensations as when a blunt object stimulates a number of receptive fields?
Definition
lateral inhibition
Term
What is a synonym for the sense of taste?
Definition
gustation
Term
What three cranial nerves innervate taste buds?
Definition
the facial nerve, the glossopharyngeal nerve, and the vagus nerve
Term
What are the five modalities of taste?
Definition
salty, sour, sweet, bitter, and umami
Term
What is the sensation of a meaty flavor?
Definition
umami
Term
Where in the brain is taste perceived?
Definition
Postcentral gyrus
Term
What physiological term is synonymous with ìthe sense of smellî?
Definition
olfaction
Term
What cranial nerve transmits impulses from olfactory receptors in the nose?
Definition
olfactory nerve
Term
What part of the brain perceives the sense of smell?
Definition
the olfactory cortex in the medial temporal lobes and the associated hippocampus and amygdaloid
nuclei
Term
What part of the brain do impulses from the olfactory epithelium bypass that the other senses do not?
Definition
thalamus
Term
Odor can powerfully evoke emotionally charged memories possibly because it linked directly to
what part of the brain that controls emotion?
Definition
limbic system
Term
What organ provides the sense of equilibrium with respect to gravity?
Definition
vestibular apparatus
Term
What are the two main parts of the vestibular apparatus?
Definition
the otolith organs and the semicircular canals
Term
What are the two otolith orgrans?
Definition
utricle and saccule
Term
What part of what bone holds the inner ear?
Definition
petrous part of the temporal bone
Term
The membranous labyrinth of the inner ear is contained within the bony labyrinth. What fluid fills
the membranous labyrinth?
Definition
endolymph
Term
What fluid fills the space between the membranous labyrinth and the bony labyrinth?
Definition
perilymph
Term
What part of the vestibular apparatus responds to changes in linear acceleration?
Definition
the otolith organs (the utricle and the saccule)
Term
What part of the vestibular apparatus responds to changes in angular (rotational) acceleration?
Definition
semicircular canals
Term
Within the vestibular apparatus what are the receptors for equilibrium?
Definition
hair cells
Term
What are all but one of the hairlike extensions of hair cells within the vestibular apparatus?
Definition
stereocilia
Term
What is the largest extension of a hair cell?
Definition
the kinocilium
Term
What happens with stereocilia are bent in the direction of the kinocilium?
Definition
the hair cell depolarizes
Term
What happens when the stereocilia of a hair cell are bent away from the kinocilum?
Definition
the hair cell hyperpolarizes
Term
What cranial nerve carries impulses from the inner ear to the brain?
Definition
the vestibulocochlear nerve (VIII)
Term
What covers the otolith organs?
Definition
a gelatinous membrane containing crystals of calcium carbonate
Term
Which of the otolith organs is more sensitive to horizontal acceleration?
Definition
utricle
Term
Which of the otolith organs is more sensitive to vertical acceleration?
Definition
saccule
Term
What causes the otolith organs to respond to changes in linear acceleration?
Definition
the inertia of the otolithic membrane
Term
How many semicircular canals are there?
Definition
three
Term
What is the orientation of the semicircular canals to one another?
Definition
They are at nearly right angles.
Term
What is the enlarged area of each semicircular canal?
Definition
the ampulla
Term
What embeds the hair cells of the semicircular canals?
Definition
a gelatinous membrane, the cupul
Term
What causes the hair cells of the semicircular canals to respond to changes in angular acceleration?
Definition
The movement of the endolymph pushes the cupula like a sail in the wind.
Term
Impulses from the vestibular apparatus are transmitted to what parts of the brain?
Definition
the cerebellum and the medulla oblongata
Term
What is the involuntary oscillations of the eyes produced by suddenly stopping a spinning of the body?
Definition
vestibular nystagmus
Term
What is a loss of equilibrium?
Definition
vertigo
Term
What are the two main characteristics of sound waves?
Definition
frequency (pitch) and intensity (amplitude)
Term
In what units is the frequency of a sound wave measured?
Definition
hertz (Hz) or cycles per second (cps)
Term
In what units is the intensity of a sound measured?
Definition
decibels (dBs)
Term
Over what range of frequency can a young, trained individual hear?
Definition
20 to 20,000 Hz
Term
What is the level of a sound that is at the threshold of hearing for a young, healthy individual with
normal hearing?
Definition
0 dB
Term
What is the average pain level produced by loud sounds?
Definition
130 dB
Term
What is the outer, fleshy part of the ear?
Definition
the pinna
Term
What is the passage way within the skull for the outer ear?
Definition
external acoustic meatus
Term
What the anatomical term for the eardrum?
Definition
tympanic membrane
Term
What is the average intensity of human speech?
Definition
60 dB
Term
What is the estimated distance of movement of the tympanic membrane when responding to normal
speech?
Definition
about the diameter of a hydrogen molecule
Term
What is the cavity between the tympanic membrane and the cochlea?
Definition
the middle ear
Term
Collectively, what are the three small bones in the middle ear?
Definition
the ear ossicles
Term
From lateral to medical, name the three ear ossicles.
Definition
malleus, incus, stapes
Term
Which of the ear ossicles is attached to the tympanic membrane?
Definition
the malleus
Term
Which of the ear ossicles is attached to the cochlea?
Definition
the stapes
Term
To what part of the cochlea is the stapes attached?
Definition
the oval window
Term
What two mechanisms help to protect the inner ear from loud sounds that have a gradual onset?
Definition
buckling of the ossicles and contraction of the stapedius muscle
Term
What structure acts as a passageway between the middle ear cavity and the nasopharynx and allows
pressure within that cavity to be equalized with pressure in the outer ear?
Definition
the auditory tube
Term
What two main structures make up the inner ear?
Definition
the vestibular apparatus and the cochlea
Term
What is the upper most of the three chambers of the cochlea?
Definition
the vestibular canal (scala vestibuli)
Term
What part of the inner ear houses the utricle and saccule?
Definition
the vestibule
Term
What is the lowest of the three chambers or canals of the cochlea?
Definition
the tympanic canal
Term
What is the middle chamber or canal of the cochlea?
Definition
the cochlear duct
Term
What is the membrane attached to the tympanic canal at the base of the cochlea?
Definition
the round window
Term
What are the individual sensory receptors of the cochlea?
Definition
hair cells
Term
What is the functional unit of the cochlea?
Definition
the spiral organ (organ of corti)
Term
Hair cells of the spiral organ are attached to what structure
Definition
the basilar membrane
Term
The stereocilia of the hair cells in the spiral organ are embedded in what structure?
Definition
the tectorial membran
Term
How are different frequency of sound detected?
Definition
Various frequencies displace the basilar membrane at different locations along the length of the spiral organ.
Term
How is the intensity of a sound coded by the spiral organ?
Definition
the louder the sound, the more frequent the impulses to the brain
Term
What cranial nerve carries impulses from the spiral organ within the cochlea to the brain?
Definition
the vestibulocochlear nerve (VIII)
Term
Where within the brain is hearing perceived?
Definition
the auditory cortices of the temporal lobes
Term
What are the two main categories of deafness?
Definition
conduction deafness and sensorineural (perceptive) deafness
Term
What type of deafness involves an impairment of sound waves from the outer ear to the cochlea?
Definition
conduction deafnes
Term
What type of deafness an impairment of the transmission of nerve impulses from the cochlea to the auditory cortex?
Definition
sensorineural deafness (nerve deafness)
Term
What is presbycusis?
Definition
age-related deafness
Term
What type of energy is light?
Definition
electromagnetic
Term
What is the range of wavelengths of visible light?
Definition
400-700 nanometers
Term
What is the outer layer of the eyeball?
Definition
the fibrous tunic
Term
What is the white, outer layer of the eyeball?
Definition
sclera
Term
What is the transparent, outer portion of the eyeball?
Definition
cornea
Term
Within the eyeball, what is the space anterior to the lens?
Definition
the anterior cavities
Term
Within the anterior cavity of the eyeball what is the space anterior to the iris?
Definition
the anterior chamber
Term
Within the anterior cavity of the eyeball, what is the space posterior to the iris?
Definition
the posterior chamber
Term
What fills the anterior cavity of the eyeball?
Definition
aqueous humor
Term
What is the pigmented muscle that controls the amount of light enter the eye?
Definition
iris
Term
What is the opening in the iris?
Definition
pupil
Term
What structure of the eye changes shape to focus images on the retina?
Definition
lens
Term
What structure encases the lens?
Definition
lens capsule
Term
What structure suspends the lens in position?
Definition
suspensory ligaments
Term
What is continuous with the iris and the choroid and produces aqueous humor from it epithelium
and contains smooth muscle to change the shape of the lens?
Definition
ciliary body
Term
What muscle works to change the shape of the lens?
Definition
ciliary muscle
Term
What structure absorbs aqueous humor?
Definition
the canal of Schlemm
Term
In what condition is aqueous humor inadequately reabsorbed leading to increased interocular
pressure?
Definition
glaucoma
Term
Within the eyeball, what is the space posterior to the lens?
Definition
the posterior cavity
Term
Within the eye, what is the gelatinous material posterior to the lens
Definition
vitreous humor
Term
What is the neural layer of the eyeball, that is the layer that holds the photoreceptors?
Definition
retina
Term
Within the eyeball, what is the pigmented layer which absorbs light?
Definition
the choroid
Term
What portion of the retina is where nerve fibers pass on their way to the brain?
Definition
the optic disc
Term
What is the blind spot of the eye?
Definition
the optic disc
Term
When light passes from one medium into another of a different density it is bent. What is the
term for this bending?
Definition
refraction
Term
What two factors influence the degree of refraction?
Definition
the difference of densities of media light that is passing through and the curvature of the interface between the media
Term
What is the part of the external world projected onto the retina?
Definition
the visual field
Term
What happens to the visual field as it passes through the cornea and lens?
Definition
it is turned upside down and backwards
Term
What is the ability of the eyes to keep an image focused on the retina as the distance between the
eye and the object varies?
Definition
accommodation
Term
What is the comparative shape of the lens when looking at distance objects (over 20 feet away)?
Definition
thin
Term
What is the comparative shape of the lens when looking at objects that are close?
Definition
thick
Term
What is the action of the ciliary muscle to make the lens thick when looking at close objects?
Definition
it contracts
Term
What is the action of the ciliary muscle when looking at objects that are far away?
Definition
in relaxes
Term
What is the shape of the ciliary muscle?
Definition
it is a sphincter, (circular)
Term
What term refers to the sharpness of vision?
Definition
visual acuity
Term
What is the ability to distinguish between two closely spaced dots?
Definition
resolving power
Term
What does it mean to have 20/20 vision?
Definition
an individual with 20/20 vision sees at 20 feet what the average person sees at 20 feet
Term
What is the medical term for nearsightedness?
Definition
myopia
Term
In what condition are near objects clearly seen, but distance object are not?
Definition
nearsightedness (myopia)
Term
In what condition are distance object clearly seen, but near objects are not?
Definition
farsightedness (hyperopia)
Term
What is the medical term for farsightedness?
Definition
hyperopia
Term
What is the usual cause of hyperopia?
Definition
the eyeball is too short
Term
What is the usual cause of myopia?
Definition
the eyeball is too long
Term
What condition occurs when the cornea or lens are not perfeclty symmetrical?
Definition
astigmatism
Term
What are the two types of photoreceptors of the eye?
Definition
rods and cones
Term
Photoreceptors synapse with what type of cells?
Definition
bipolar cells
Term
Bipolar cells of the retina synapse with photoreceptors and what cells which send fibers to the
brain?
Definition
ganglion cells
Term
What visual pigment is within rods?
Definition
rhodopsin
Term
What type of visible light is not absorbed by rods?
Definition
red
Term
What are the two components of rhodopsin that it breaks into when it absorbs light?
Definition
opsin, retinaldehyde
Term
What action occurs when rhodopsin absorbs light and breaks into its component parts?
Definition
bleaching
Term
What are the two forms of retinal?
Definition
all-trans and 11-cis form
Term
Which form of reinal is attached opsin?
Definition
11-cis
Term
Which form of retinal forms when light strikes rhodopsin?
Definition
all-trans
Term
Where is the all-trans form of retinal transformed back into the 11-cis form?
Definition
pigment epithelial cells
Term
What is the interaction between photoreceptors and pigment epithelial cells in which the all-trans
form of retinal is converted to the 11-cis form?
Definition
the visual cycle of the retinal
Term
What is the gradual increase in photoreceptor sensitivity in low light?
Definition
dark adaptation
Term
What is the action of photoreceptors in the dark?
Definition
they release an inhibitory neurotransmitter which hyperpolarizes bipolar cells preventing them from depolarizing
Term
What depolarizes photoreceptors in the dark?
Definition
Na+ channels remain open creating a dark current
Term
What causes photoreceptors to hyperpolarize in light?
Definition
11-cis retinal converts to the all to the all-trans form and dissociates from opsin. opsin changes shape and causes G-proteins to dissociate thus activating an enzyme that converts cGMP to GMP. This conversion of cGMP to GMP closes Na+ channels and hyperpolarizes the cell.
Term
What type of photoreceptor has a lower threshold to light and gives better night vision?
Definition
rods
Term
What type of color vision do human have?
Definition
trichromatic color vision
Term
What are the three types of cones?
Definition
blue, green, and red
Term
What region of the retina has the greatest visual acuity?
Definition
the fovea centralis
Term
What larger region of the retina contains the fovea centralis?
Definition
macula lutea
Term
What type of photoreceptor occurs in the fovea centralis?
Definition
only cones
Term
What is the ratio of cones to ganglion cells in the fovea centralis?
Definition
1 to 1
Term
There are approximately 120 million rods and 6 million cones in each retina. Only about 1.2
million nerve fibers leave the eye. This illustrates that what phenomenon occurs between
photoreceptors, bipolar cells, and ganglion cells?
Definition
convergence
Term
Where on the retina does convergence not occur?
Definition
fovea centralis
Term
Which half of the visual field is transmitted to the same side of the brain as that side of the body
the eye occurs on?
Definition
the temporal half
Term
Which half of the visual field is transmitted to the opposite side of the brain as that which the eye
occurs on?
Definition
nasal half
Term
Within what structure does crossing over (decussation) of optic fibers occur?
Definition
optic chiasma
Term
In what part of the brain is vision perceived?
Definition
the visual cortex of the occipital lobe
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