Term
|
Definition
| Phenytoin, carbamazepine, sort of lamotrigine |
|
|
Term
|
Definition
| gabapentin, benzodiazepines (diazepam, lorazepam), phenobarbital (GABA A) |
|
|
Term
|
Definition
|
|
Term
| First line for tonic clonic |
|
Definition
| phenytoin, carbamazepine, valproic acid |
|
|
Term
|
Definition
| benzodiazepines, phenytoin for prophylaxis |
|
|
Term
| Major rules for which epilepsy drugs to given when |
|
Definition
| Ethosuximide is first line for absence; benzodiazepine and phenytoin for status; phenytoin, carbamazepine and valproate for tonic-clonic; simple and complex partial can be treated with everything by ethosuximide and benzodiazepines |
|
|
Term
| First line for trigeminal neuralgia |
|
Definition
|
|
Term
| First line in pregnant women |
|
Definition
Phenobarbital
*Get them on monotherapy!! |
|
|
Term
|
Definition
|
|
Term
|
Definition
| First line is MgSO4, next use benzodiazepines |
|
|
Term
| Mixed mechanism of action |
|
Definition
|
|
Term
|
Definition
| Sedation, tolerancec, dependence |
|
|
Term
|
Definition
| Induces p450, blood dyscrasias (agranulocytosis, aplastic anemia), hepatotoxicity, ataxia, diplopia, tertogenic |
|
|
Term
|
Definition
| GI distress, urticaria, fatigue, SJ syndrome, headache |
|
|
Term
|
Definition
| Sedation, tolerance, dependence, induces p450 |
|
|
Term
|
Definition
| Nystagmus, diplopia, ataxia, sedation, gingival hyperplasia, hirsutism, megaloblastic anemia, teratogenic, SLE-like syndrome, induces p450 |
|
|
Term
|
Definition
| GI distress, rare but fatal hepatotoxicity (esp young children), spina bifida in fetus, tremor, weight gain, CONTRAINDICATED IN PREGNANCY |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Sedation, mental dulling, kidney stones, weight loss |
|
|
Term
|
Definition
| tonic clonic seizures, also used as a Class IB anti-arrhythmic |
|
|
Term
|
Definition
| Lorazepam, diazepam, triazolam, temazepam, oxazepam, midazolam, chlordiazepoxide, alprazolam |
|
|
Term
| Clinical use of benzodiazepines |
|
Definition
| Anxiety, spasticity, status epilepticus (lorazepam and diazepam), detoxification, night terrors, sleepwalking |
|
|
Term
|
Definition
|
|
Term
| Main causes of status epilepticus |
|
Definition
| Withdrawal from EtOH or barbituates, medication non-compliance |
|
|
Term
| Other clinical uses of valproate |
|
Definition
| migraine, bipolar disorder |
|
|
Term
|
Definition
| Penetrating head wounds, severe head trauma/stroke, severe neo-natal hypoxia, genetics |
|
|
