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Second Messengers
Signal Transduction
5
Biochemistry
Graduate
12/16/2010

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Term
This secondary messenger is used by cells to regulate many diverse activities:muscle contraction, secretion, metabolism,neuronal excitability, and proliferation.
Definition
Calcium cation:Ca2+
Term
Fact: Cells respond more to the calcium concentration rather than to the ion itself.
Definition
Term
Calium OFF mechanism
Definition
Remove Ca from cytoplasm by pumping it from the cell or back into internal stores
Term
two types of calcium pumps
Definition
Na/Ca exchanger
-plasma membrane calcium pump
Term
How do the Calcium pumps work
Definition
-When [Ca] is high the Na/CaX is actively working. when the [Ca] becomes low the Na/CaX loses efficiency and the plasma membrane pumps use ATP to pump out two ions of Ca.
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