Term
| RNA Viruses belong to groups? |
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Definition
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Term
| Types of III, dsRNA Viruses? |
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Definition
| Reoviradae--Rotavirus, Orbivirus, Orthoreovirus |
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Term
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Definition
| Naked, 2 icosahedral capsid shells, 10 dsRNA segments each encoding a protein, gastroenteritis in kids, tetravalent attenuated vaccine no longer used called "Rotashield" |
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Term
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Definition
| Colorado Tick Fever, causes viremia, infects RBC precursors, headache, fever, chills, photophobia, myalgia, arthralgia, lethargy |
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Term
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Definition
| mild cold of GI discomfort, first members of the fam. to be discovered |
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Term
| Types of Type IV (+) ssRNA Viruses? |
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Definition
| Picornaviradae, Caliciviradae, Togaviradae, Flaviviridae, Coronaviradae |
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Term
| Types and gen. char. of Picornoviradae? |
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Definition
Small, Naked Icosahedral, cytolytic
Enteroviruses, Hep A, Rhino Virus |
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Term
| Types and chars. of Enteroviruses? |
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Definition
transmitted oral-fecal route
Polio: 3 serotypes, 95% no symp, 4-8% aseptic meningitis, 1% flacced paralysis, after intestinal entry infects motor neurons, OPV (live), eIPV(dead)
ECHO virus
Enterovirus 70-hemorrhagic:
conjunctivitis
Enterovirus 71: encephalitis
Coxackie Virus A and B: A=soft palatte lesions(herpangia)/hand-foot-mouth dis. B=myocarditis/pericarditis |
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Term
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Definition
| short incubation,not cytolytic but a budder unlike other picornaviradae, inactivated vaccine (Harvix), no chronic infec., contam. food |
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Term
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Definition
| acid-labile, cold, grow a 33 deg C, 200+ serotypes |
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Term
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Definition
| naked icosahedral, slightly larger than picornaviradae, fecal-oral |
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Term
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Definition
Norwalk Virus=60% of non-bac. gastroenteritis
Hep E: causes epidemic outbreaks in poor unsanitary parts of the world |
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Term
| Char. and types of Togaviridae? |
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Definition
Enveloped, Icosahedral
Arboviruses: Eastern, Western Venezualen Equine Enchephalits, mosquitos
Rubiviruses: rubella=german measles, could possible lead to cataracts, deafness, congenital heart disease, cerebral and developmental delays |
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Term
| Char and types of Flaviviradae? |
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Definition
Arboviruses=fevers, hemorrhagic, encephalitis=yellow fever, dengue, st. louis, japanese encephalitis, west nile encephalitis
Powassan Encephalitis is tick bourne
West Nile=20% mild illness, 1/150 severe
Dengue=break-bone fever, dengue shock syndrome from reinfection
Hep C=STD/blood bourne |
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Term
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Definition
| enveloped, helical, can cause SARS |
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Term
| Types of Type V (-) ssRNA viruses? |
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Definition
Orthomyxoviridae(Influenxaviradae)
Paramyxoviridae
Rhabdoviridae
Filoviradae
Bunyaviradae
Arenaviradae |
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Term
| Char of Orhtomyxoviradae/influnezaviridae? |
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Definition
helical, enveloped, virus replicates in superficial respiratory and destroy ciliated columnar
H1, H2, H3 hemagluttinin
N1, N2 neuaraminadase
Antigenic drift=chance mutations
Antigenic shift=reassortment between strains, ducks |
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Term
| Char. and types of Paramyxoviridae? |
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Definition
enveloped, helical, genome is unsegemented, formation of syncytium by F protein, respiratory transmission
Parainfluenza, mumps, measles, RSV |
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Term
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Definition
| Bullet shaped, enveloped, negri bodies, rabies, long incubation allows for post-infect treament to be effective |
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Term
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Definition
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Term
| Char and types of Bunyaviridae? |
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Definition
enveloped, helical, no matrix protein
Arbovirus: Lacrosse encephalits, California Encephalits
Hanta Virus: Hantaan, Seoul, Sin Nombre, cause Acute Respiratory Distress Syndrome (ARD) and possible kidney dysfunction |
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Term
| Char and Types of Arenaviridae? |
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Definition
enveloped, helical, no matrix protein, sometimes host ribosomes in particle
Lassa Virus
Lymphocytic Choriomeningits (LCM)= from house mice, if transmitted from mother to fetus in utero, the baby will have every cell in its body infected but mount no cyotoxic response and will be fine, otherwise fatal |
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Term
| Example of unclassified RNA viruses? |
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Definition
| Hep D, tiny circular (-)ssRNA, needs coinfection to be active |
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Term
| Char and Types of Class VI, Retroviridae? |
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Definition
enveloped, 2 identical copies of (+)ssRNA, contain some tRNA needed as a primer for transcription and Reverse Transcriptase
Ocornavirinae
Lentivirinae |
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Term
| Types and Char of Oncornavirinae? |
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Definition
cause sarcomas, leukemias, and lymphomas
Human T Lymphocyte Viruses: HTLV-I causes adult T-cell leukemia (ATL) and possibly tropical spastic parapeis(TSP) and myelopathy(HAM)
HTLV-II may lead to hairy cell leukemia
have tax and rex, promotes transcription of NF-kB and IL-2 |
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Term
| Types and Char of Lentivirinae? |
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Definition
| HIV! CXCR-4 on Ts and CCR5 on macrophages, M tropic first than T-tropic, infected macrophages disseminate infection throughout the body, |
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