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SABS I-BW #8
Therapeutics
10
Other
Professional
11/28/2011

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Cards

Term
Therapeutic Index
Definition
Lethal dose in 50% / Effective Dose in 50%
Term
Certain Safety Factor
Definition
Takes biological diversity into account
Term
Standard Safety Margin
Definition
(LD01-ED99)/ED99 x 100
Term
Therapeutic Window
Definition
the range of plasma drug concentrations with a high probability of therapeutic success
Term
Side Effects
Definition
predictable reactions
Term
Pseudo-allergy
Definition
A nonimmunologic, anaphylaxis-like reaction of sudden onset
(from medical dictionary online)
Term
Antagonism
Definition
2 drugs that oppose each other in their pharmacological effects
Term
Potentiation
Definition
Combination results in an effect of one that is greater than expected
Term
Summation
Definition
Additive effects of 2 drugs that share the same pharmacological effects
Term
Synergism
Definition
Combination results in pharmacological effects that are greater than the maximum effects of either given alone
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