Term
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Definition
-ALL adrenergic receptors
-Effects: ↑systolic BP(β1), ↓Dia BP (β2),↑HR, ~TPR
–
Uses: Allergic reaction, Anaphylactic shock, Glaucoma, hypotension |
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Term
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Definition
-Acts on α1, α2, β1
-Effects: ↑Systolic BP(β1), ↑Diastolic BP(NO β2),↓HR, ↑TPR, REFLEX BRADYCARDIA
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Uses: Hypotension, septic shock |
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Term
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Definition
α1 agonist
Effects: ↑SysBP, ↑DiaBP, ↓HR, ↑TPR, REFLEX BRADYCARDIA)
–
Uses: Pupillarydilation, nasal decongestant, rebound congestion |
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Term
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Definition
-α2 agonist
-Effects: ↓BP, sedation, analgesia, ↓aqueous humor production
-A/E: hypertensive crisis (upon sudden withdrawal), xerostomia, sexual dysfunction
-Uses: Open angle glaucoma (Apraclonidine), hypertension, DOA withdrawl |
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Term
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Definition
-β receptor agonist
-Effects: ↑SysBP (due to ↑contractility), ↓DiaBP, ↑↑HR, ↓TPR, REFLEX TACHYCARDIA
-Uses: AV Block, torsade de pointes |
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Term
| Albuterol/Salmeterol (Longer acting) |
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Definition
-β2 receptor agonist
-Effects: Bronchodilation, enhanced mucociliary clearance
-Uses: COPD, Asthma, Hyperkalemia, premature labor |
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Term
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Definition
-Acts on:
D1(low doses)
β1(intermediate doses)
α1(high doses)
-Effects: Renal vasodilation, increased Cardiac output
-Uses: Cardiogenic shock w/ poor renal perfusion |
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Term
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Definition
-β1 receptor agonist
-Effects: ↑Contractility/Conduction of heart
-Uses: Cardiogenic Shock |
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Term
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Definition
-Irreversibly Blocks α1 and α2receptors
-Effects: ↓HR, ↓TPR
-Use: Pheochromocytoma (first treatment, then use β‐blockers) |
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Term
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Definition
-α1 blocker
-Effects: Vasodilation,
-Adverse Effect: postural hypotension (first dose syncope), sexual dysfunction
-Uses: Overflow continence (internal sphincter), Raynaud’s dz, BPH (Tamsulosin –relaxes prostatic capsule) |
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Term
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Definition
General Effects: ↓Contractility/CO, ↓ aqueous humor production, hypoglycemia
A/E: Sexual dysfunction
Contraindications: Diabetes, Asthma, Depression, Elderly,
Uses: hypertension, open‐angle glaucoma (timolol), Migraine/Panic Attack (situational anxiety) |
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Term
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Definition
| Non‐Selective BETA BLOCKER |
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Term
| what are the SELECTIVE beta 1 blockers? |
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Definition
| 1‐BEAM (Betaxolol, Esmolol, Atenolol, Metoprolol) |
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Term
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Definition
-Partial Agonist at β receptors
-α1 antagonist
-used in Congestive Heart Failure |
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Term
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Definition
-Antagonist at α1and βreceptors
-used in CHF |
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Term
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Definition
| Releases stored catecholamines |
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Term
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Definition
Prevents NE reuptake
-↑ Sympathetic NS |
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Term
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Definition
Like Epi, but longer (>2 min) and less potent
*used for nasal drops |
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Term
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Definition
Converts in methyl‐NEP
–agonist at α2receptors |
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Term
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Definition
-Releases NE in the synapse
-can cause hypertensive crisis when used with MAOi |
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Term
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Definition
| blocks TYROSINE HYDROXYLASE |
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Term
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Definition
CHOLINE ESTER-acts on Nm and Nn (no AChE breakdown)
Use for:
-BLADDER and BOWEL problems (neurogenic bladder, post operative ileus)
-xerostomia
A/E –Nausea and vomiting, bronchospasm, flushing/hypotension |
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Term
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Definition
CHOLINE ESTER-acts on Nm and Nn (no AChE breakdown)
-used for Glaucoma
-A/E –Cyclospasm (impaired far vision) |
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Term
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Definition
Natural Alkaloid--> acts on Nm only
-Use in open‐angle glaucoma, xerostomia
-A/E –Salivation , sweating, nausea, bronchospasm, tremors
-C/I in asthma, COPD, and cataracts |
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Term
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Definition
binds IRREVERSIBLY
-Poisoning cause DUMBBELSS (Diarrhea, Urination, Miosis, Bronchospasm, Bradycardia, SM excitation, Lacrimation, Salivation, Sweating)
-Treat with Atropine and Pralidoxime if NO AGING |
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Term
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Definition
| reversible AChE inhibitor --> short acting |
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Term
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Definition
-reversible AChE blocking
-NO CNS
-used in MG, postop reversing of NMJ blockade |
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Term
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Definition
| Used for glaucoma and Atropine OD |
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Term
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Definition
ANTIMUSCARINIC --> Blockage of Nm
-Uses: Organophosphate Poisoning, CVS disorders, opthalmology
-Poisoning Effects: Hot(Temp),Dry(anhydrosis), Red (flushing), Blind(cycloplegia-->TREAT WITH PHYSOSTIGMINE |
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Term
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Definition
ANTI-MUSCARINIC
-Used in Motion Sickness |
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Term
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Definition
ANTI-MUSCARINIC
Used in Urge incontinence (prevents urge) |
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Term
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Definition
ANTI-MUSCARINIC
-Parkinson’s med (‘Park’ my ‘Benz’ ) |
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Term
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Definition
Only anti‐Muscarinic that doesn’t ↓ mucus clearance
-Used for asthma and COPD |
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Term
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Definition
GANGLIONIC BLOCKERS
-Baroreceptor reflex block…look out for questions (ex: no reflex bradycardia when given NE) |
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