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S3 Ross Pharm Local Anesthetics
Azim
8
Pharmacology
Professional
11/23/2009

Additional Pharmacology Flashcards

 


 

Cards

Term
What is the MOA of most local anesthetics?
Definition
Inhibition of sodium ions through sodium channels in nerve membranes.
Term
When does the strongest binding of local anesthetics occur. In other words what state is the nerve in?
Definition
Inactivated state. Remember that hyperkalemia will enhance the effect of local anesthetics due to depolarization and hypercalcermia will antagonize local anesthetics.
Term
Name a topical local anesthetic that is an ester.
Definition
Cocaine. Recall that it blocks reuptake of catecholamines.
Term
Name two short action local anesthetics.
Definition
Procaine and Chloroprocaine. Recall that if the drug is a short action or topical that it must be an ester.
Term

What is an easy way to remember all the amide local anesthetics?

 

What about all the Long action amide locals?

Definition

All the amides have "i" in the beginning of the name (Lidocaine, Priolocaine, Mepivacaine, Bupivacaine, Etidocaine, Ropivacaine).

 

If you were in MERP, you have a LONGER path to get through med school. MERB are all the LONG action drugs. Mepivacaine, Etidocaine, Ropivacaine, Bupivacaine.

Term
The only long lasting ester local anesthetic (that we learn about)
Definition
Tetracaine
Term
A local anesthetic that can cause lethal arrhythmias.
Definition
Bupivicaine
Term
This drug is NOT the DOC for local anesthetic purposes in the case of local infiltration.
Definition
Tetracaine.
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