Term
| What is the MOA of most local anesthetics? |
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Definition
| Inhibition of sodium ions through sodium channels in nerve membranes. |
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Term
| When does the strongest binding of local anesthetics occur. In other words what state is the nerve in? |
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Definition
| Inactivated state. Remember that hyperkalemia will enhance the effect of local anesthetics due to depolarization and hypercalcermia will antagonize local anesthetics. |
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Term
| Name a topical local anesthetic that is an ester. |
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Definition
| Cocaine. Recall that it blocks reuptake of catecholamines. |
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Term
| Name two short action local anesthetics. |
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Definition
| Procaine and Chloroprocaine. Recall that if the drug is a short action or topical that it must be an ester. |
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Term
What is an easy way to remember all the amide local anesthetics?
What about all the Long action amide locals? |
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Definition
All the amides have "i" in the beginning of the name (Lidocaine, Priolocaine, Mepivacaine, Bupivacaine, Etidocaine, Ropivacaine).
If you were in MERP, you have a LONGER path to get through med school. MERB are all the LONG action drugs. Mepivacaine, Etidocaine, Ropivacaine, Bupivacaine. |
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Term
| The only long lasting ester local anesthetic (that we learn about) |
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Definition
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Term
| A local anesthetic that can cause lethal arrhythmias. |
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Definition
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Term
| This drug is NOT the DOC for local anesthetic purposes in the case of local infiltration. |
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Definition
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