Term
| Describe the genome type for Herpesviridae. |
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Definition
| Linear dsDNA. It is a large complicated strand. |
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Term
| Name the type of protein responsible to help the virus take over the host cell and affect the immune response. |
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Definition
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Term
| One of the 3 subfamilies of herpes viruses which include HCMV and HHV-6/7. Note these ARE able to infect WBCs. |
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Definition
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Term
| One of the 3 subfamilies of herpes which infect WBCs and are oncogenic. Note some of these include EBV and HHV-8. |
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Definition
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Term
| A period of intermittence or non-infectious period in a virus. |
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Definition
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Term
| Describe the replicate cycle of herpesvirus. |
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Definition
| Upon cell entry, alpha/beta-RNA produce proteins used for DNA replication. This ends up producing gamma-RNA. Which encodes for viral replication DNA. |
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Term
| HCMV ( a beta herpes virus) aka HHV-5 leads to what two diseases? |
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Definition
Cytomegalic inclusion disease
Infectious monocucleosis. Most people have this virus. |
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Term
| What happens if you get HHV in utero or at birth if you are immunocompromised? |
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Definition
| CNS damage for a minority. BUT most of them will be asymptomatic. |
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Term
| What herpes virus(s) cause Roseola infantum? |
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Definition
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Term
| Post natal patients, Blood transfusion and organ transplant patients and immunocompromised patients are at risk for what virus? |
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Definition
| HCMV. Note that the degree of immunocompormise would determine what disease you will get. |
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Term
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Definition
| Real-time PCR and serology. Ganciclovir |
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Term
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Definition
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