Term
| Barbiturates-long, intermediate, and short acting uses |
|
Definition
Long-->PHENOBARBITAL (generalized tonic/clonic seizures)
Intermediate-->PENTOBARBITAL
Short-->THIOPENTAL (anesthetic) |
|
|
Term
| BENZODIAZEPINES-long acting |
|
Definition
-chlordiazepoxide
-clonazepam
-diazepam
-flurazepam
-alprozolam XR |
|
|
Term
| BENZODIAZEPINES-intermediate acting |
|
Definition
-temazepam
-lorazepam
-flunitrazepam
-alprazolam
-oxazepam |
|
|
Term
| BENZODIAZEPINES-short acting |
|
Definition
|
|
Term
|
Definition
-acute anxiety attacks
-GADs
-panic attacks
-seizures
-muscle spasms
-alcohol withdrawal treatment |
|
|
Term
|
Definition
anxiolytic-->MOA unknown (partial 5HT receptor agonist)
-used for non drowsy results
-used in patients with previous alcohol problems
-not immediately effective |
|
|
Term
| name the Z hypnotics-->uses, MOA |
|
Definition
ZALEPLON--> shortest acting
ZOLPIDEM --> medium acting
ESZOPICLONE-->longest acting
-selective alpha1 GABA channel
-used for sleep onset insomnia |
|
|
Term
|
Definition
activates melatonin receptors in suprachiasmatic nucleus
-sleep onset insomnia
-abuse liability is absent |
|
|
Term
| affects of BARBITURATES on p450 enzymes? |
|
Definition
|
|
Term
| liability of OVERDOSE-->BARBS and BENZOS? |
|
Definition
BARBITURATES can cause overdose
BENZOS rarely cause overdose when used alone, can when mixed with alcohol, barbs, etc. |
|
|
Term
| what is the BENZO ANTAGONIST? |
|
Definition
|
|
Term
| why are BENZODIAZEPINES not prescribed to SLEEP APNEA patients? |
|
Definition
| could decrease respiratory center's sensitivity to HYPERCAPNIA (high CO2 levels in blood) |
|
|
