Term
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Definition
-1st line treatment of BIPOLAR disorder
-PROPHYLACTIC treatment of BIPOLAR and MANIC disorders
-SCHIZOEFFECTIVE disorder in combo with antipsychotics |
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Term
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Definition
-Mentally and physically HYPERACTIVE
-elevated mood
-Disorganized behavior
-incessant talking and flight of ideas
-Speech is pressured--> rhymes and puns
-GRANDIOSE DELUSIONS --> feelings of self importance |
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Term
| mania with a contrary MOOD SWING is known as what? |
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Definition
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Term
| what is LITHIUM's relationship with Na+? effects on neural tissue? |
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Definition
-Li+ substitutes for Na+ in all Na+ compartments, Na+ is lost , and lithium retained
-Lithium is especially toxic to nervous tissue
-very narrow THERAPEUTIC INDEX |
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Term
| what must every patient have done prior to beginning lithium therapy? testing what? |
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Definition
pretreatment WORKUP
-tests renal function-> excreted by kidney
-ECG--> can cause cardiac problems
-CBC--> can increase WBC and PLATELET levels |
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Term
| does LITHIUM act immediately? what is often given conjointly? |
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Definition
| doesn't work immediately, therefore ANTIPSYCHOTICS (OLANZAPINE) are often given to tide patients over until effective |
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Term
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Definition
| INHIBITS adenylyl cyclase--> decreases cAMP |
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Term
| **common ADVERSE SIDE EFFECTS** KNOW THESE |
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Definition
-fine hand TREMOR
-thirst and POLYURIA
-***nephrogenic DIABETES INSIPIDUS
-weight gain
-benign diffuse GOITRE
-worsening SKIN PROBLEMS
**CARDIAC EFFECTS and interstitial NEPHRITIS |
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Term
| what drug is often used now in place of LITHIUM? |
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Definition
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