Term
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Definition
-opioid receptor ANTAGONIST
-used for OPIOID OVERDOSES--> reverses opioid effects
-short acting-->may require several injections |
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Term
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Definition
-opioid receptor ANTAGONIST
-blocks effects of illicit opioids
-used to control relapse in ALCOHOLISM
-longer acting than NALOXONE |
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Term
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Definition
-mu receptor AGONIST--> slow acting
-used in SUBSTITUTION THERAPY for OPIOID/HEROIN addicts--> patients will go into centers and get daily dose LOWER THAN HEROIN LEVELS which help control physical affects of withdrawal without the same intoxicating effects
-acute effects similar to MORPHINE in high enough doses (respiratory depression, constipation, miosis, etc) |
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Term
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Definition
-mu receptor PARTIAL AGONIST
-used to reduce cravings of OPIOID addicts--> often in combination with NALTREXONE
-long half life |
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Term
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Definition
-nicotinic acetylcholine PARTIAL AGONIST (alpha4 beta2 receptors)
-used in SMOKING CESSATION--> blunts rewards of smoking |
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Term
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Definition
-benzo, increases GABAa opening frequency
-used in ALCOHOLICS to prevent withdrawal seizures, hallucinations, delirium tremens |
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Term
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Definition
-NMDA glutamate antagonist
-used in treatment of ALCOHOLISM--> effective WITH COUNSELING
-may be neuroprotective
-can have ADVERSE CVS EFFECTS |
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Term
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Definition
-inhibits ALDEHYDE DH--> leads to ACETALDEHYDE BUILDUP which causes NAUSEA and VOMITING, HEADACHE, HYPOTENSION
***knowledge of adverse effects hopes to curb urge to drink |
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