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Ruminant
Ruminant GI diseases
105
Other
Professional
03/22/2010

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Term
coccidiosis in goats
Definition
eimeria arloingi
Term
coccidiosis in sheep
Definition
eimeria ovina
Term
coccidiosis general
Definition
host specific, obligate intracellular--destroy GI mucosa
Term
coccidiosis affects what age group in SR?
Definition
young; older=immunity
Term
coccidiosis disease occurs when
Definition
stress, change diet, weather, parturition, weaning
Term
coccidiosis diarrhea consistency (yum)
Definition
water, mucous, usually not bloody
Term
coccidiosis CS in SR
Definition
fever, anorexia, dehydration, wknss, wt loss, death, subclinical=decreased production
Term
coccidiosis diagnosis in SR
Definition
fecal float
Term
coccidiosis tx in SR
Definition
sulfa drugs, amprolium (10X cattle dose), monensin (risk of toxicity)
Term
coccidiosis prevention
Definition
manure management, decrease stocking rate, manure disposal, elevate feeders
Term
tapes in SR?
Definition
moniezia
Term
tapes in SR worrisome for O. or SR?
Definition
O
Term
tapes diagnosis in SR
Definition
white proglottids in feces
Term
tapes tx in SR
Definition
deworm w/FBZ (keep in rotation)
Term
GI scours (SR)
Definition
E. coli, rota/corona virus, Crypto
Term
GI scours in SR
Definition
neonatal diarrhea, similar to calves
Term
GI enterotoxemia in SR
Definition
Clostridium perfingens
C=necrotic enteritis, hemorrhagic enterotoxemia
D=pulpy kidney
Term
clostridium type C CS
Definition
<1week old; FPT; toxin is sensitive to trypsin (trypsin inhibitors in colostrum
Term
clostridium type D CS
Definition
biggest lambs; older lambs>kids on grain feed; sudden convulsive death; Hglycemia, glucosuria
Term
clostridium/GI enterotoxemia Tx
Definition
clostridial antitoxins, oral abx
Term
clostridium/GI enterotoxemia prevention
Definition
Vaccinate: ewes/does 1 mo b4 parturition, kids follow label; dairy goats might need q6Mos
minimize feed changes, gradual, bacterin/toxoids
Term
abomasal emptying defect
Definition
idiopathic/suffolk (black faced breeds)
Term
idiopath abomasal emptying CS
Definition
wt loss, abd distension, anorexia
Term
abomasal emptying Dx
Definition
increased rumen chloride, necropsy
Term
Johne's disease SR
Definition
mycobacterium avium ssp. paratuberculosis
Term
Johne's facts
Definition
2-5 YO, sheep strains more diff to cure
Term
Johnes CS and Dx
Definition
pasty>fluid diarrhea, wt. loss, emaciation
Histo (acid fast) of ileum, ileocecal LNN, serology, special culture, DNA probes
Term
Johnes control
Definition
Cull (AGID and ELISA surveillance)
Term
Clinical mastitis SR
Definition
sheep=coagulase (-) staph>S. aureus, M. haemolytica
Goats=less M. haemolytica
uncommon, <5% lactations
Term
clinical mastitis SR tx
Definition
no IMM drugs approved; use extralabel and extended w/d times (1/2 cow dose)
cannula w/tomcat cath
mycoplasma/gangrenous=no tx
Term
subclinical mastitis SR
Definition
S. aureus, Strep, Corynebacterium, Mycoplasma
20-40% SR
Term
subclinical mastitis SR Dx
Definition
Culture; SCC/CMT: goats have higher % neuts normally (500K-1 mill)
SCC increases in late lactation
Term
subclinical mastitis SR Tx
Definition
IMM abx at dry-off or weaning
extended w/drawl time
Term
caseous lymphadenitis
Definition
corynebacterium pseudotuberculosis
Term
CL in goats
Definition
external
Term
CL in sheep
Definition
visceral
Term
CL transmission
Definition
close contact, abrasions, ingestion
Term
CL diagnosis
Definition
Culture, ELiSA, SHI
Term
CL tx
Definition
cull, isolation, drain (pets)
Term
CL prevention/control
Definition
Vx, quarantine, cull, sanitation; Vx for sheep only, decreases signs but doesn't eliminate
Term
Orf
Definition
DNA poxvirus
adult sheep>goat
Term
Orf CS
Definition
proliferative pox lesions on lips, gums, teats, etc
nonfatal if they keep on eating
self limiting
Term
Orf control
Definition
Vx, not used much scarified into skin
Term
scrapie (prion like BSE) CS
Definition
progressive encephalitis, pruritis, excitement, fine tremors, ataxia
adult sheep>goats
Term
urolithiasis SR
Definition
most common at urethral process
castrated bucks/wethers>intact males
increase phosphate, decreased water
Term
SR urolithiasis Tx
Definition
urethral relaxants, urinary acidifiers
Sx=snip off urethral process; tube cystotomy>PU
Term
SR urolithiasis prevention
Definition
increase water access, Ca:P ratio=2:1, salt, NH4Cl to acidify urine
Term
copper toxicity
Definition
sheep, young
acute hemolytic crisis
Dx=Cu in blood, liver, kidney, feed
tx=molybdenum, ammonium tetrathiomolybdenate
Cu proper in diet
Term
listeria
Definition
soil
CS=meningoencephalitis, unilateral CN signs
Tx=penicillin, tetracycline
Term
test for FPT in calves (herd program)
Definition
serum total protein
want TP>5.5
Term
FPT test for single sick calf
Definition
sodium sulfite turbidity test
positive turbidity w/18% Na sulfite=1000mg/dl IgG
Term
sequela to FPT in calves
Definition
septicemia
polyarthritis (E. coli, salmonella, M. bovis)
meningitis (E. coli)
Term
gut closure in calves
Definition
absorption best 4-6 hrs
decreased sharply by 12 hr
closure by 24 hr
** need volume/quality colostrum in first 6-12hrs
Term
factors affecting passive transfer
Definition
time=earlier better
colostral IgG conc=beef>>dairy
volume fed (volume X conc=mass IgG)
mass varies=time of milking, dry period length, nutrition, parity
IgG decreases rapidly after calving
IgG decreases rapidly w/time
Oxytocin--more milk--dilutes IgG
Term
Enterotoxigenic E. coli
Definition
K99 pathogenic
<3 days old
Normal GI flora fecal oral
calves born late at greater risk, increased environmental load
Term
ETEC pathogenesis
Definition
adhesin in pilli--adheres to enterocytes--heat stable enterotoxins--activates cGMP--Hsecreation of Cl- from crypts
As abomasal pH decreases to<3 (by day 2-3),no problem
Term
ETEC lesions
Definition
no damage to villi
secretory diarrhea
Term
ETEC CS
Definition
watery, yellow diarrhea, no blood, no tenesmus
High fecal pH (secretory=increase bicarb in feces)
Term
ETEC Dx
Definition
Rarely done; must ID spec, strain
FAb for K99 pillus
Latex agg assay for K99
Term
ETEC Tx
Definition
hydration oral/IV fluids,
Abx=ceftioufur, sulfas, amoxicillin
Term
ETEC prevention
Definition
Vax dam late gestation
clean housing
Oral vax (monoclonal Ab for K99) to calf in emergency outbreak
Term
Rotavirus in calves data
Definition
dsRNA virus, non enveloped
calves 5-15dd
fecal oral
stable in pH/temp
Term
Rotavirus pathogenesis
Definition
infects SI villous epi--kills cells--villous atrophy--epi cells replaced w/immature cells w/decreased lactase--malabsorption
Term
rotavirus lesions
Definition
villous atrophy
malabsorption
small secretory from viral endotoxin
Term
rota CS
Definition
high morb, low mort
infected 24 hrs, diarrhea until immature epi cells mature
Term
rota Dx
Definition
fecal EM
other=FAb, ELISA, PCR
Term
rota tx and prevention
Definition
no spec tx
management, isolate new arrivals, sic; handle sick 1st,
vax dam late gestation (oral vax for newborns no good)
Term
corona data
Definition
ssRNA
calves 4-30dd
fecal oral
environment
some resp tx.
unstable at pH<3, <45 degrees
Term
corona pathogenesis
Definition
infects SI and LI villous epi and crypts--villous sloughing, villous fusion--maldigestion + malabsorption
Term
corona lesions
Definition
villous slough/fusion
S/LI lose colonic ridges
malabsorption
Term
corona CS
Definition
watery yellow diarrhea, no blood/tenesmus
+/- mild resp
Term
corona Dx
Definition
Fecal EM
FAb, ELISA, RIA (not avail)
Term
corona tx. and prevention
Definition
non specific
Vx dam late gestation
decrease fecal exposure, clean stalls, disinfect, grow out of eventually
Term
crypto in calves data
Definition
protozoa
5-30dd old
fecal oral, +/- aerosol
Term
crypto lesions in calves
Definition
villous atrophy, crypt Hplasia, trophozoites and schizonts in GI epi
malabsorptive diarrhea
Term
crypto in calves CS
Definition
white-yellow diarrhea, +/- blood
diarrhea for many days
Term
crypto in calves Dx
Definition
oocysts in feces: iodine, acid-fast, saffranin-meth blue; flotation w/Sheathers
IF of feces
definitive=see it in feces
ELISA
Term
crypto in calves tx
Definition
none specific
ZOONOTIC
good mgmt; oocysts destroyed by freezing or drying
10^5-10^7 oocysts/mL feces=diagnosis
Term
salmonella in calves
Definition
5-42dd
dublin, typhimurium
fecal oral
some airborne
persistent, killed by heat
+/-Zoonotic
Term
salmonella path
Definition
enterotoxin=hypersecretion
cytotoxin=decreased protein synthesis, cell death, increased permeability
ingest--through GI wall--mesenteric LNN--liver, septicemia
Term
salmonella CS
Definition
malabsorptive and secretory (lots of fluid loss)
septicemia, sudden death, fever
bloody, tenesmus, mucous shreds
anorexia, leukopenia
Term
salmonella dx
Definition
fecal culture
fecal PCR
CBC=degen L shift
serology=herd surveillance
Term
salmonella tx
Definition
ceftioufur
fluids
NSAIDS
Term
salmonella control
Definition
mgmt
Vax not great, mutant gram - decreases severity of CS
use milk replacer (dublin shed in milk)
NOT Himmune serum
Term
nutritional diarrhea of calves
Definition
don;t feed poor quality milk replacer (soy)
Term
attaching and effacing E Coli (EHEC)
Definition
15-30dd
ZOONOTIC
Term
EHEC path
Definition
attach to enterocytes--verotoxins--necrosis+slough enterocytes
Term
EHEC lesions/CS
Definition
epi slough @BM
malabsorptive
watery diarrhea
bright red blood
Term
EHEC Dx
Definition
culture E Coli + typing (prove toxin production,verotoxins)
Term
coccidiosis in calves
Definition
eimeria zurneii, bovis
>30dd (PPP is 16-30dd, cannot see in calves<3wks old)
Term
coccidiosis in calves CS
Definition
LI diarrhea (low volume, not watery)
bloody, mucosa shreds, tenesmus
Term
coccidiosis in calves Dx
Definition
FEC=quantitative
Histo=typhlocolitis w/coccidial organism
Term
coccidiosis in calves tx and prevention
Definition
no speccific tx
decrease stocking rates
no feed on ground
anticoccidial=ionophores, decoq, amprolium
Term
giardia in calves
Definition
fecal oral
most subclinical
malabsorptive diarrhea
Term
giardia in calves Dx
Definition
fecal wet mount or ZnSO4=motile trophozoites
Term
giardia tx and prevention
Definition
FBZ
Term
Depression score I
Definition
alert active normal
BD of calf <8d=0
BD of calf >8d=7
Term
depression score II
Definition
depressed, slow, lethargic
BD of calf <8d=5
BD of calf >8d=11
Term
Depression score III
Definition
sternal recumbency, weak suckle
BD of calf<8d=12
BD of calf>8d=16
Term
depression score IV
Definition
lateral recumbency, absent suckle
BD of calf<8d=13
BD of calf>8d=20
Term
% dehydration
normal (<6%)
Definition
normal demeanor
eyes normal
no skin tent
Term
% dehydration
mild (6-8%)
Definition
depressed
eyes sunk 2-4mm
1-3s skin tent
Term
% dehydration
moderate (8-10%)
Definition
depressed
eyes sunk 4-6mm
skin tent 2-5sec
Term
% dehydration
severe (10-12%)
Definition
comatose
eyes sunk 6-8mm
5-10sec skin tent
Term
% dehydration
death (>12%)
Definition
dead
eyes sunk 8-12mm
>10sec skin tent
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