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RT Antihyperlipidemic drugs
RT Antihyperlipidemic drugs
9
Pharmacology
Not Applicable
09/16/2012

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Cards

Term
Select an antihyperlipidemic drug that is most effective at reducing LDL (bad) cholesterol.
Definition
Statins
Term
Select an antihyperlipidemic drug that is most effective at reducing triglyceride levels.
Definition
Fibrates (gemfibrozil, Lopid; fenofibrate, Tricor)
Term
List the drugs that reduce cholesterol by binding to bile acids in the intestinal tract (bile acid sequestrants).
Definition
colestipol (Colestid)
cholestryramine (Questran)
colesevelam (Welchol)
Term
Describe the side effects of bile acid sequestrants. (should mention reduced absorption of fat soluble vitamins [A,D,E,K]
Definition
Constipation
Flatulence
Nausea
heartburn
Term
Describe the precautions taken when taking other medications while taking bile acid sequestrants.
Definition
Take other drugs 1 hour before or 4 hours after bile acid sequestrant
Term
Describe the side effects of statins.
Definition
Muscle aches and weakness
Abdominal pain
Headache
Constipation
Upper respiratory infection
Term
Select an antihyperlipidemic drug that is most effective in raising HDL (good) cholesterol.
Definition
fenofibrate (Tricor)
niacin, vitamin B3
Term
Describe a common side effect of taking niacin (vitamin B3).
Definition
Flushing is most common side effect
Term
Describe the measures used to decrease the flushing associated with immediate release niacin (vitamin B3).
Definition
Take aspirin before niacin
Start with low dose and titrate upward slowly
Use sustained-release formula
Take food or milk with the niacin
Abstain from alcohol or hot drinks around the time niacin is taken
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