| Term 
 
        | What are the major adverse outcomes of Delirium in the Elderly |  | Definition 
 
        | - prolonged hospital stay (8d longer) - increased mortality while in hospital and in months following d/c
 - increased risk of complications: hospital acquired infection, pressure ulcers, incontinence and falls)
 - poor physical and cognitive recovery at 6 and 12mo w lower MMSE scores at d/c
 - increased risk of placement at residential home
 - increased risk of developing dementia in pts w no cognitive impairment at baseline
 |  | 
        |  | 
        
        | Term 
 
        | What are the types of delirium |  | Definition 
 
        | 1) hyperactive (30%) 2) hypoactive delirium (25%)
 3) mixed delirium (45%)
 |  | 
        |  | 
        
        | Term 
 
        | What are the DSM-IV criteria for delirium |  | Definition 
 
        | 1) disturbance of consciousness (focus, inattention, reduced awareness) 2) change in cognition (or perceptual change, w memory deficits, disorientation, language disturbance
 3) develop over hours to days and fluctuate throughout day
 |  | 
        |  | 
        
        | Term 
 
        | What are the common non-correctable risk factors for delirium |  | Definition 
 
        | 1) age - male
 - mild cognitive impairment, dementia, parkinsons disease
 - multiple comorbiditis: renal/hepatic disease, CVA hx, hx of falls, poor mobility, hx of prior delirium
 |  | 
        |  | 
        
        | Term 
 
        | What are the major correctable factors for delirium development |  | Definition 
 
        | - hearing impairment/visual impairment - malnutrition, dehydration, low albumin
 - social isolation, sleep deprivation, new environment, moves w/i hospital
 - restraints and indwelling catheters
 - new addition of three/more medication
 - no time orientation
 - smoking
 |  | 
        |  | 
        
        | Term 
 
        | What are hte major precipitating factors for delirium |  | Definition 
 
        | - polypharmacy - alcohol w/d and benzodiazepines
 - sepsis, shock, hypothermia
 - lyte disturbance
 - endocrine disturbance
 - nutritional deficiencies
 - cardiac, liver, or renal failure
 - pulmonary disorder
 - VCA/seizure
 - post-sgx
 - falls and fx
 - anemia/GI bleed
 - pain
 - Ca and terminal illness
 |  | 
        |  | 
        
        | Term 
 
        | A drop in what number from basline MMSE indicates delirium? A rise in what number indicates resolution of delirium? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the components to the confusion assessment method? |  | Definition 
 
        | 1) acute onset and fluctuating course 2) inattention
 3) disorganized thinking
 4) altered mental status
 
 *(1) and (2) required; (3) OR (4) required
 |  | 
        |  | 
        
        | Term 
 
        | What is the sn and sp of the CAM for delirium |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are key components to the investigation of the delirious patient |  | Definition 
 
        | - targeted blood tests: lytes, Cr, glucose, CBC - u/a
 - occult infection search
 - EKG
 - post-void residual bladder scan
 - CXR
 - head CT
 
 Additional tests:
 - TFT, Thyroid Ab
 - drug levels
 - toxicology
 - B12/folate
 - syphilis serology
 - lumbar puncture
 - EEG
 - vasculitis screen including ANA and ENA
 |  | 
        |  | 
        
        | Term 
 
        | What is a potential biochemical marker for delirium |  | Definition 
 
        | - C-reactive protein (both predict incidence of delirium and recovery from it |  | 
        |  | 
        
        | Term 
 
        | What is the prognosis for delirium at 12 mo |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are clinical features of autism spectrum disorders |  | Definition 
 
        | - lack of eye contact - atypical language in rate, rhythm,intonation, and pronoun reversals
 - sterotypy
 |  | 
        |  | 
        
        | Term 
 
        | Describe seonsory processing problems in autism spectrum disorders |  | Definition 
 
        | - touch: defensiveness vs no pain - vision: difficulty with contrast
 - auditory: loud noises very painl
 - smell: may want to smell objects/intolerance to odors
 - taste: picky eaters vs eating everything
 |  | 
        |  | 
        
        | Term 
 
        | What is the characteristic learning method for autism spectrum disorders |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | For autism spectrum pts What is the first part of the physical exam that should be performed? What is the last part that should be performed? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Define: 
 macule
 patch
 papule
 plaque
 nodule
 tumor
 |  | Definition 
 
        | 1) flat lesion 0-1cm 2) flat lesion 1+cm
 3) raised lesion 0-1cm
 4) raised lesion 1+cm
 5) palpable lesion 0-2cm within the dermis/subcutis
 6) palpable lesion 2+cm within the dermis or subcutis
 |  | 
        |  | 
        
        | Term 
 
        | Define: well marginated skin lesion |  | Definition 
 
        | - transitions from normal to abnl skin within 1mm |  | 
        |  | 
        
        | Term 
 
        | What layer of skin accumulates in hyperkeratotic skin? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - vesicle 1+cm in diameter |  | 
        |  | 
        
        | Term 
 
        | Define: 
 telangiectasia
 lichenification
 excoration
 fissure
 purpura
 |  | Definition 
 
        | 1) fixed, visible dilated blood vessel within the epidermis accentuation of normal skin lines due to persistent rubbing or scratching
 - erosion/ulcer caused by scratching, rubbing, or picking
 - linear split in skin through the epidermis and into the dermis
 - extravasated blood in the skin (palpable)
 |  | 
        |  | 
        
        | Term 
 
        | What are hte components to the ABCDE method of skin lesion ID for melanoma |  | Definition 
 
        | 1) asymmetry - border
 - color
 - diameter
 - evolution
 |  | 
        |  |