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Respiratory Pharmacology
Pharmacology
14
Pharmacology
Graduate
06/08/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

Respiratory Pharmacology includes 

 

Antitussives

Decongestants

Antihistamines

Mucolytics & Expectorants

           and 

6 Agents used to treat  Asthma, Bronchitis, Emphysema

 

1. Beta _________ Agonists

2. Xanthine Derivatives

3. Anticholinergics

4. Cromones

5. _______________

6. Leukotriene Inhibitors

Definition

Antitussives

Decongestants

Antihistamines

Mucolytics & Expectorants

           and 

6 Agents used to treat  Asthma, Bronchitis, Emphysema

 

1. Beta Adernergic Agonists

2. Xanthine Derivatives

3. Anticholinergics

4. Cromones

5. Glucocorticoids

6. Leukotriene Inhibitors

Term

Antitussives 

(ex: Robitussin DM)

 

Action: _________

Therapeutic Effect: Reduces Cough

Side Effects: ___________

Definition

Action: 

Inhibits cough by direct effect on brainstem.


Therapeutic Effect:

Reduces Cough


Side Effects: 

Retention of secretions related to cough supression.

Term

Decongestants 

(Ex: Sudafed)

 

Action : ___________

Therapeutic Effect: Reduces local congestion of nasal pathway.

Side Effects: __________

Definition

Action : 

Binds with alpha receptors in blood vessels of the nasal mucosa to stimulus vasoconstriction.


Therapeutic Effect:

Reduces local congestion of nasal pathway.

 

Side Effects:

Nervousness, increased blood pressure.

Term

Antihistamines

(Ex: Benadryl)

 

Action:  Blocks the action of histamine on upper respiratory tissues.

Therapeutic Effect: Treatment of allergic symptoms.

Side Effects: _______________

Definition

Action:  

Blocks the action of histamine on upper respiratory tissues.

 

Therapeutic Effect:

Treatment of allergic symptoms.

 

Side Effects: 

Sedation, fatigue, dizziness, nausea.

Term

Mucolytics & Expectorants

(Ex: Robitussin/ Mucomyst)

 

Action: _________

Therapeutic Effect: Treatment of coughs associated with upper airway infections.

Side Effects: rarely noted, dizziness, nausea.

Definition

Action:

1. Expectorants increases respiratory tract fluids.

2. Facilitate the production and ejection of mucus; mucolytics decrease the             viscosity of secretions.

3. Ejection of secretions.


Therapeutic Effect:

Treatment of coughs associated with upper airway infections.

 

Side Effects:  

rarely noted, dizziness, nausea.

Term

6 Pharmacologic agents used to treat/prevent of diseases of airway obstruction 

(Asthma, Bronchitis, Emphysema)

 

1._______ Adernergic Agonists

2. Xanathine Derivatives

3. ________________

4.Cromones

5. Glucocorticoids

6. ___________ Inhibitors

Definition

1.Beta Adernergic Agonists

2. Xanathine Derivatives

3. Anticholinergics

4.Cromones

5. Glucocorticoids

6. Leukotriene Inhibitors

Term

Beta Adrenergic Agonists

This drug has both a Short Acting Beta Agonist (SABA)  as well as a                                                 Long Acting Beat Agonist (LABA)

 

Action: __________

Therapeutic Effect: prevents or inhibits airway obstruction in bronchospatic                                      disease.

Side Effects: ______________

Definition

Action:

1. Short or long term acting stimulation of beta receptors.

2. Relaxation of bronchiole smooth muscles. 


Therapeutic Effect: prevents or inhibits airway obstruction in bronchospatic                                  disease.

 

Side Effects:

Nervousness, shaking, tremors, restlessness, tachycardia, palpitations, paradoxical, bronchospasms.

Term

 

This will probably be on the exam!!

 

What is the difference between short acting and long acting beta andrenergic agonists.

Definition

Short Acting = rescue medication

Long Acting = chronic medication

Term

Xanthinge Derivatives 

 

Action: ________

 

Therapeutic Effect: Prevent bronchochonstriction in obstructive airway disease.

 

Side Effects: Toxicity that presents as nausea, irritability, restlessness.

Definition

Action: 

1. Possible blocking of adensosine.

2. Smooth muscle relaxation; possible blocking of phosphodiesterase (PDE)

3. Inhibition of inflammatory response.

 

Therapeutic Effect:

Prevent bronchochonstriction in obstructive airway disease.

 

Side Effects:

Toxicity that presents as nausea, irritability, restlessness.

Term

Anticholinergics

Examples:

Ipratropium = Short

Tiotropium = Long

 

Action: _________________

Therapeutic Effect:  Improves airway flow in bronchospastic diseases.

Side Effects: ____________

Definition

Action:

1. Short or long acting muscarinic receptor blockers.

2. Reduction of acetylcholine induced bronchoconstriction.


Therapeutic Effect:

Improves airway flow in bronchospastic diseases.


Side Effects:

Constipation, dry mouth, blurred vision, urinary retention 

CANT SHIT, SPIT, SEE, OR PEE

Term

Cromones

(Mast cell Stabalizers)

 

Action:

1. Inhibits the release of inflammatory mediators. 

2. Reduction of histamine and leukotrienes. 

 

Therapeutic Effect: _________

 

Side Effects: nasal and upper respiratory tract irritation following inhalation.

Definition

Action:

1. Inhibits the release of inflammatory mediators. 

2. Reduction of histamine and leukotrienes. 

 

Therapeutic Effect: 

Prophylaxis; prevention of asthma attacks prior to activities that are known to precipitate an asthma attack (exercise, exposure to animal hair)

 

Side Effects: nasal and upper respiratory tract irritation following inhalation.

Term

Leukotriene Inhibitors

(Ex: Singular)

 

Action: Reduces the synthesis of leukotrienes or blocks the receptors for                         leukotrienes.

 

Therapeutic Effect: ________

 

Side Effects: Liver dysfuction noted rarely.  

Definition

Action: Reduces the synthesis of leukotrienes or blocks the receptors for                         leukotrienes.

 

Therapeutic Effect: 

Managment of the inflammatory component of bronchoconstrictive diseases. 

 

Side Effects: Liver dysfuction noted rarely.  

Term

Glucocorticoids 

 

Action: ________

Therapeutic Effects: Treatment of inflammation associated with hyperresponsive

                               airways.

Side Effects: __________

Definition

Action: 

Inhibit proinflammatory products (cytokines, prostoglandins, leukotrienes) while increasing antiinflammatory proteins.


Therapeutic Effects: Treatment of inflammation associated with hyperresponsive airways.

 

Side Effects: 

GI bleed, dyspepsia, hyperglycemia, delayed wound healing, osteoperosis, fluid retention, hypertension, "MOON FACE", truncal obesity, acne.

Term

The treatment of Cystic Fibrosis Includes 1 Goal and 5 Pharmacologics

 

Goal

1. ______ airway patency.

 

Pharmacologics

1. Bronchodialators

2. __________ and Expectorants

3. Glucocorticoids

4. ____ Infectives

5. Others: ??

Definition

Goal

1. ______ airway patency.

 

Pharmacologics

1. Bronchodialators

2. Mucolytics and Expectorants

3. Glucocorticoids

4. Anti Infectives

5. Others: ??

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