Term
|
Definition
long duration bronchodilator for COPD
M3 muscarinic acetylcholine receptor antagonist. It blocks the MsAch recepto to reduce cGMP causing smooth muscle relaxation to dilate the bronchi. |
|
|
Term
|
Definition
| long duration bronchodilator for moderate/severe asthma management. selective beta-2-adrenoceptor agonist. It activates beta-2-GPCR leading to cAMP mediated smooth muscle relaxation to dilate bronchi |
|
|
Term
|
Definition
short duration bronchodilator for asthma or COPD.
It is a selective beta-2-adrenoceptor agonist causing cAMP mediated smooth muscle relaxation to dilate bronchi |
|
|
Term
|
Definition
anti-inflammatory steroid used with inhalers to treat severe asthma.
Forms a complex with glucocorticoid receptor which then acts as a transcriptional regulator to down regulate inflammatory mediators.
ADRS= immune suppression and osteoporosis
contra= diabetic |
|
|
