Shared Flashcard Set

Details

Resp drugs
pharm 2 final
47
Health Care
Graduate
05/05/2009

Additional Health Care Flashcards

 


 

Cards

Term
first gen. anti-histamines
Definition

diphenhydramine

chlorphemiramine

bropheniramine

dimenhydrinate

meclizine

hydroxyzine

cyproheptadine

Term
2nd gen anti-histamines
Definition

loratadine

fexofenadine

cetirizine

Term
do 1st or 2nd gen anti-histamines cross the BBB?
Definition

1st -> CNS SE's

 

Also + anticholinergic SE's

Term
which 2nd gen anti-hist is met by P450?
Definition
loratadine
Term
do 2nd gen anti-hists bind w/ muscarinics receptors?
Definition
NO
Term
intranasal anti-hist
Definition
azelastine
Term
which is more effective azelastine or nasal steroids?
Definition
steroids!
Term
decongestants
Definition

phenylephrine

pseudoephrine

naphazoline

tetrahydrozoline

oxymetazoline

xylometazoline

Term
decongestant MOA
Definition

stimulate alpha receptors-> vasoconstr.

 

 

Term
do decongestants effect itching, sneezing, or rhinorrhea?
Definition
NO just decongestants
Term
why should decongestants not be used > 5 days?
Definition
rebound congestion
Term
why should decongestants not be used w/ MOAI's and TCA's?
Definition
HTN crisis!
Term
what drugs should decongestants NOT be taken w/?
Definition
MAOI's and TCA's
Term
intranasal steroids are used for
Definition
mod-severe allergic rhinitis
Term
how long does it take for nasal steroids to take effect?
Definition
12 hrs after 1st dose, max=3-14 days
Term
nasal steroids for dry noses
Definition

beclamethasone

fluticasone

triamcinolone

Term
nasal steroids for wet noses
Definition

triamcinolone

beclamethasone

budesonide

Term
oral steroids for allergies
Definition

prednisone

methylpredisone

 

***severe only!***

 

Term
how long should oral steroids for allergies be taken?
Definition
5-7 days
Term
what meds are for acute exac of asthma
Definition

SA beta agonists

systemic steroids

anticholinergics

Term
beta 2 selective asthma drugs
Definition

albuterol

terbinafine

levalbuterol

pirbuterol

Term
which B-2 selective has fewer S/E and better bronchodilation
Definition
levalbuterol
Term
beta agonists MOA asthma
Definition

relax bronchial sm. mm

incr h2o content -> incr clearance of mucus

Term
LA beta agonists
Definition

salmeterol

formoterol

Term
which LA beta agonist should be given w/ steroids
Definition
salmeterol
Term
SQ or IV beta-2 agonists
Definition

terbutaline

epi

Term
SE beta agonists
Definition

tachy

tremors

hyperglycemia

dysryhtmias

Term
mexylthanthine drug
Definition
theophylline
Term
is theophylline used more for asthma or COPD tx?
Definition
COPD
Term
MOA theophylline
Definition

block phosphodiesterase (break down cAMP)

anti-infamm

decr neurotoxins

Term
does theophylline have narrow or wide TI?
Definition
NARROW!
Term
AE theophylline
Definition

GI

CNS

CV

Term
DI's theophylline
Definition

cimetidine

Macrolides

Erythro

Term
inhaled antimuscarinic drugs
Definition

ipratropium

tiotropium

Term
MOA inhaled anti-muscs
Definition
inhibit ACh bronchocxn-> decr mucus
Term
inhaled anti-muscs should not be used in pts w/
Definition
BPH, glaucoma
Term
steroids for asthma
Definition

beclomethasone

triamcinolone

fluticasone

flunisolide

budesonide

Term
steroids MOA for asthma
Definition

decr inflamm and obxn

 

potentiate B-2 effects

Term
steroids are used for _______ in asthma
Definition
prevention!
Term
SE's steroids for asthma
Definition

dysphonia,  oral yeast

gluacoma, cateracts

Term
leukotriene mods for asthma
Definition

zarfirlukast

montelukast(CystLT antag)

 

zileuton(5-lipoxygenase -I)

Term
leukotriene mods used to decr or stop use of what drugs
Definition

steroids!

 

as ADJUNCTS!!

Term
which leukotriene mod is approved for use in kids?
Definition
montelukast
Term
which leukotriene mod requires LFT monitoring?
Definition
Zileuton
Term
mast cell stabilizers
Definition

cromylin NA

nedocromil

Term
immunomodulator for asthma
Definition
omalizumab
Term
mgmt of exacerbatiosn
Definition

MG

heliox

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