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Research Design and Measurement
Research Methods and Designs in Social Sciences
220
Psychology
Undergraduate 4
08/17/2010

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Term
Psychometrics
Definition
Field of study concerned with the theory and practical applications of education and psychological measurement
Term
Psychological measurement
Definition
Assignment of numbers to objects or events according to some rule
Term
Construct
Definition
Abstract concepts or qualities that do not physically exist but which we attempt to measure
Term
Variable
Definition
An attribute, quality, or entity that can assume different values across people or things
Term
Operational definition
Definition
Statement of the process or procedure used to measure or manipulate a construct
Term
Error
Definition
Deviation of an observed measurement from it's "true value"
Term
Systematic error
Definition
Deviations caused by constructs other than the desired construct
Term
Random error
Definition
Deviations caused by nonsystematic chance variation in other influences (how you felt that morning, pencil slips, etc.)
Term
Reliability
Definition
Extent to which a measure produces consistent observed scores
Term
Validity
Definition
Extent to which a measure accurately reflects the desired construct
Term
Reliability coefficient
Definition
Percentage of observed score variance accounted for by true score variance
Term
Test-retest reliability
Definition
Correlation between the scores of people who have responded to a measure twice
Term
Inter-rater reliability
Definition
Consistency of two or more observers' measurements of a single event
Term
Internal consistency reliability
Definition
Consistency of scores for all items in a single measure
Term
Standard Error of Measurement (SEM)
Definition
Standard deviation around an individual's true score
Term
Content validity
Definition
Extent to which items or observations of a measure/variable accurately represent all domains of the construct of interest
Term
Criterion validity
Definition
Extent to which items or observations of a measure/variable accurately predict construct-relevant outcomes/behaviors
Term
Construct validity
Definition
Extent to which items or observations of a measure/variable accurately reflect the unobserved construct it claims to measure
Term
Measure deficiency
Definition
Degree to which the measure does not asses the entire domain of the construct
Term
Measure contamination
Definition
Degree to which the measure assesses things that are not related to thin construct of interest
Term
Measure relevance
Definition
Degree to which the measure assesses the construct domain
Term
Content domain
Definition
Total set of behaviors, categories, thoughts, etc. that could be used to measure a specific construct.
Term
Validity coefficient
Definition
The correlation between the predictor and the outcome
Term
Predictive validity
Definition
Relationship between predictor and criterion measured in the future.
Term
Concurrent validity
Definition
Relationship between predictor and a criterion measured currently
Term
Internal structure validity
Definition
Degree to which items in a single measure form meaningful patterns of inter-correlations
Term
Convergent validity
Definition
Degree to which the measure correlates with other measures of the same construct
Term
Discriminant validity
Definition
Degree to which the measure correlates with other measures of different constructs
Term
Factor
Definition
Group of item, scale, or observational rating that seem to "hang together" to describe a broader, more generalizable construct
Term
Nomological net
Definition
Theoretical network of construct-to-construct associations stated at an abstract level
Term
Jingle fallacy
Definition
Belief that because measures are called by the same name, they are measuring the same thing
Term
Jangle fallacy
Definition
Belief that because measures are called by different names, they are measuring different things
Term
External validity
Definition
Whether we can observe the same relationships across different samples, settings, and times
Term
Sampling
Definition
Procedure by which individuals are selected to participate in a research study
Term
Population
Definition
Set of all people, objects, or events of interest to the researcher
Term
Population element
Definition
A single member of the population
Term
Stratum
Definition
Mutually exclusive subsets of the population each containing population elements that possess a common characteristic
Term
Representative sample
Definition
A group of population elements that has approximately the same distribution/proportion of characteristics as the population from which they were drawn
Term
Sampling error
Definition
Difference in the distribution of characteristics between the sample and the population as a whole
Term
Sampling error variance
Definition
Measure of the degree of sampling error across multiple samples (avg. sampling error across groups)
Term
Probability sampling
Definition
Sampling method in which every element of the sampled population has a known probability of being valued in the sample
Term
Nonprobability sampling
Definition
Sampling method in which there is no way to estimate the probability each element has of being included in the sample
Term
Simple random sampling
Definition
Sampling method in which all population elements AND all possible combinations of sample elements have the same chance of being selected
Term
Stratified random sampling
Definition
Sampling method in which population is divided into homogeneous subgroups and sample random samples are drawn from each subgroup
Term
Cluster sampling
Definition
Sampling method in which random samples are drawn from larger randomly selected clusters from the population
Term
Accidental (convenience) sampling
Definition
Sampling method in which the most readily available individuals are selected
Term
Purposive sampling
Definition
Sampling method in which a specific subset of individuals are targeted for inclusion in the sample
Term
Quota sampling
Definition
Sampling method in which individuals are selected non-randomly according to a fixed quota
Term
Proportional quota sampling
Definition
Sampling method that attempts to represent the major characteristics of a population by sampling a proportional amount of each characteristic
Term
Non-proportional quota sampling
Definition
Sampling method which specifies the minimum # of units desired for each category, and samples until these minimums are achieved.
Term
Snowball sampling
Definition
Sampling method in which members of the initial sample enlist other members of the target population who meet the criteria for inclusion
Term
Interview bias
Definition
Characteristics of either the interviewer's appearance or the manner by which a question is asked
Term
Response rate
Definition
% of people in initial sample who actually complete the survey/provide data
Term
Nominal scale
Definition
Scale in which numbers simply serve as labels for different categories
Term
Ordinal scales
Definition
Scale in which numbers represent specific ordering or hierarchical ranking
Term
Interval scale
Definition
Scale in which numbers represent real amounts of something AND reflect relative differences in magnitude, but there is not true zero
Term
Ratio scales
Definition
Scale in which numbers represent real amounts of something, reflect relative differences in magnitude, AND there is a true zero
Term
Graphic rating scales
Definition
Person indicates "how much" of something they possess by placing a mark at the appropriate point on a line that runs from one extreme of an attribute to the other
Term
Single rating scale
Definition
Scale used to provide responses to multiple items in a measure
Term
Impact studies
Definition
Studies where purposeful manipulation of the IV is meant to have a direct impact on participant's behavior
Term
Judgment studies
Definition
Studies where set of conditions are presented/provided and participants are asked to respond to the stimulus materials
Term
Observational studies
Definition
Studies where detailed observations of naturally occurring behaviors or interactions are made over time
Term
Mundane realism
Definition
Extent to which a study/lab task resembles the real world
Term
Experimental realism
Definition
Extent to which a study/lab task is psychologically meaningful to participants
Term
Experimenter expectancy
Definition
Expectations held by researcher influence either the manner by which respondents behave or the measurements obtained int eh study
Term
Demand characteristics
Definition
Participants act, think, or feel in ways that they think the researcher wants them to
Term
Good participant role
Definition
Participant tries to figure out the experimenter's hypotheses and purposely confirm them
Term
Bad participant role
Definition
Participant tries to figure out the experimenter's hypotheses and purposely disconfirm them
Term
Apprehensive participant
Definition
Participant is so concerned about being evaluated by the experimenter that they act in a socially desirable manner
Term
Faithful participant
Definition
Participant blindly does exactly what the experimenter tells him to do
Term
Universalistic scope
Definition
Investigate theoretically predicted associations between constructs that can occur in any location, place, or time
Term
Particularistic scope
Definition
Interested in the association/effect that will be obtained in a particular setting, population, time
Term
Basic scope
Definition
Term
Neurons
Definition
Specialized cells that convey sensory information into the brain
(.5-1 mm) or 50-100 microns. 100-200 billion of them.
Term
Glial cells
Definition
provide supporting functions to neurons
(1/10 size of a neuron) - 1000-2000 billion. No nerve impulse.
Term
Cell body
Definition
Area of the neuron that contains the nucleus and integrates messages from other neurons
Term
Monopolar neuron
Definition
(Type of neuron that is RECEPTOR NEURONS IN SKIN) Short stalk from cell body divides
in two branches to form dendrites
and axon.
Term
Bipolar neuron
Definition
(Type of neuron that is OLFACTORY SYSTEMS) One axon and one dendrite are
on opposite sides of the cell body
Term
Monopolar neuron
Definition
(Type of neuron that is MOTOR NEURON) Dendrites extend in several
directions from the cell body with
one axon.
Term
Resting potential
Definition
Electrical charge across the membrane when the cell is at rest
Term
Interneurons
Definition
Inhibitory - between afferent and efferent neurons
Term
Shwann cell
Definition
Myelin in peripheral nervous system (outside of brain and spinal cord).
Term
Oligodendrocyte
Definition
Myelin in the brain and spinal cord.
Term
Astrocyte
Definition
Makes up the blood-brain barrier; assists neurons in chemical uptake
Term
Microglia
Definition
Garbage pickers of nervous system; activated in response to injury.
Term
Voltage
Definition
Ability for the flow of ions.
Term
Pyramidal neurons
Definition
Excitatory - type of multi
Term
Stellate neurons
Definition
Type of mutli neuron that is either excitatory or inhibitory
Term
Function of neuron
Definition
Conduct nerve impulse - send info from point A to point B
Term
Glial cell function
Definition
Make it go faster - helps neurons - no nerve impulse conduction.
Term
Anions
Definition
Negative ions - chloride (Cl-), protein molecules (A-)
Term
Regulation of ions through membrane require...
Definition
Pumps and channels

Pumps- requires energy to pump in a certain number of ions and pump out a certain number

Channels- channels closed at rest but open with a change in the voltage of the cell. Energy not required
Term
Action potential
Definition
Brief and massive depolarization at the axon of a neuron (typically -55 mV).

Used by neurons to tell others when they are activated
Term
Voltage-sensitive channel
Definition
Not all channels open at the same time, but rather in a specific sequence
Term
Pre-synaptic terminal
Definition
The neuron that is sending information and contains vesicles and neurotransmitters.
Term
Synapse
Definition
The site of chemical transmission and uses ligand gated channels.
Term
3 types of synapses
Definition
Axo-dendritic, Axo-somatic, and Dendro-dendritic.
Term
Inhibitory Post-Synaptic Potentials (IPSP)
Definition
Resting potential is made more negative (Hyperpolarization) –i.e. GABA
Term
Actions potentials
Definition
Self sustaining, All-or-none property, brief, voltage-gated
Term
Postsynaptic potentials (PSP
Definition
Graded, Proportional to stimulus, long-lasting, ligand-gated
Term
Functions of the neuron (RITD)
Definition
Receive, integrate, transform, and distribute information.
Term
Steps of neurotransmitter release
Definition
1. Action Potential leads to release of vesicles
2. Vesicles release contents (neurotransmitters and ions) into the synaptic cleft
3. Neurotransmitters bind to receptors on post-synaptic area
4. Channels open and ions flow into cell causing EPSP or IPSP.
Term
Lock and key model
Definition
Ionotropic Receptor
Term
Up-regulation
Definition
Increase the number of receptors because too few neurotransmitters
Term
Down regulation
Definition
Decrease the number of receptors for certain neurotransmitter
Term
Agonist
Definition
Increases the amount of a certain neurotransmitter which means more receptors are open
Term
fMRI
Definition
Inject you with a marker - iron will show you where blood is flowing
Term
MRI
Definition
Magnet that looks at excitation of cells - snapshot of electrons
Term
PET scan
Definition
glorified x-ray - poor man’s fMRI - looks at radioactive decay - usually looks at glucose (will accumulate in areas that are active), but can be anything labeled with a radioactive ligand (good for cancer- whole body scans)
Term
EEG
Definition
Brain waves at depth of cortex
Only good for looking at cortexes - not specific brain regions
Term
Gross Brain Pathology (invasive)
Definition
Look for large structural changes - obvious malformations
Term
Gross dissection
Definition
This shows blood in the brain – a sign of hemorrhage (stroke)
Term
Electrophysiology
Definition
give a little electricity, see what the cells do
Term
Polymerase (invasive) Chain Reaction
Definition
Blood amplifier to see DNA
Term
Histology (invasive)
Definition
Taking tissue from the living state and now being able to look at it under the microscope

Technique to section tissue and allows for further investigation
Range of thicknesses at which tissue may be sectioned
Thickness based on tool to be used
Term
Stereological Quantification (invasive)
Definition
Determination of the number of items within the tissue (neurons, glia, cells expressing a certain protein, etc)
Term
Immunocytochemistry (invasive)
Definition
Allows you to precisely visualize just one (or multiple, if you can) item

Need to know the protein of interest so that an antibody can be created against it


Gives pretty pictures

Due to the potential confound of amplification, not the purest true estimator of numbers

Use antibody against specific protein
Excellent tool for localization
Not best for quantity estimation
Term
Electrophysiology (invasive)
Definition
Can turn things on and off (a lot of different receptors and channels) and see what the response is
- Because of this work, can figure out exactly what a drug does and where it works in an animal

Sophisticated technique that allows you to document individual cell or cell population functioning
Can look at sub-components of cells (e.g. channels)
Can stimulate and/or record
Term
High Performance Liquid Chromatography (HPLC) (invasive)
Definition
- Look at time-locked changes in release of neurochemicals following some event
Term
Right hemisphere
Definition
For all senses except taste, the right hemisphere “controls” the left “side” of the body

Non-language sounds, music, geometric patterns, faces, spatial ability, emotional content, nonverbal memory, touch
Term
Left hemisphere
Definition
Words, letters, language sounds, complex movements, speech, writing, reading, verbal memory
Term
Somatic nervous system
Definition
Composed of the spinal nerves
These nerves receive sensory information from the periphery, and respond with motor action (e.g. move leg when touches thorn)
Afferent and efferent information sent along same nerves
Dorsal portion of spinal cord: Carries sensory information
Ventral portion of spinal cord: carries motor information
Term
Autonomic NS
Definition
Parasymp and symp
Term
Sympathetic
Definition
All nerves originate along the spinal cord
- These start in the ganglia (little balls of neurons outside of spinal cord)
Term
Parasympathetic
Definition
All nerves are pretty much in the brain
- Insetead of ganglia, PSP uses cranial nerves
Term
Acetylcholine (sympathetic)
Definition
Released from the ventral horn of the Spinal Cord

Causes release of norepinephrine from the sympathetic chain ganglion


Parasympathetic: Uses cranial nerves (ACh release from ganglia)
Term
Horizontal plane
Definition
Horizontal sheet through brain
Term
Saggital plane
Definition
Between my eyes
Term
Coronal plane
Definition
Vertical through middle of head
Term
Phineas Gage
Definition
Probably the most famous person to have survived severe damage to the brain. He is also the first patient from whom we learned something about the relation between personality and the function of the front parts of the brain.
Term
Cell Fate
Definition
Some cells become neurons while others become glial cells
Cell fate is dictated both by genetics and environment
In the early brain, local environment (where a cell is created) plays the greatest role
Term
Region/location and cell fate
Definition
Where you are from determines what you can become
Term
Where does neurogenesis occur during development?
Definition
Occurs early in development to determine what cells will be.
Term
Granule cell neurogenesis
Definition
Granule cells are generated throughout the life of the individual (not the case for most regions of the brain)
Term
Cell Generation/Neurogenesis
Definition
1)Determines the maximal number of neurons in a given region of the brain

2) Occurs early in development for a specified period of time.
Term
Cell migration
Definition
Determines the ability of a cell to get from the site at which it was generated to its final destination.
Term
How do cells migrate?
Definition
From the SubVentricular Nucleus
With the use of glial scaffolds
Term
Chemoaffinity Hypothesis
Definition
A chemical signal or trail is what a cell uses to get from point A to B, and stabilizes the connections when the cell finally arrives at point B

The basis for our thinking on brain development
Term
Trophic factors
Definition
Growth factors
Term
Chemoattraction
Definition
Cell attraction to a location.
Term
Chemotrophism
Definition
Cell survival
Term
Fetal Alcohol Syndrome Facial change
Definition
1) Thin lip
2) Flattening of nose or short nose
3) Flat midface

Short palpebral fissures
Ears abnormal
Low nasal bridge
Epicarnial folds
Micrognathia
Indistinct philtrum
Term
FAS structural changes
Definition
Effects the entire brain since occurs a long duration of development

Chronic insults tend to
have global effects on the brain
Term
Structural changes with lead
Definition
Most profound effects on the frontal
lobe, as opposed to FAS which affects the entire brain.

Effects on dividing cells (since occurs in children, only observed in late maturing regions of the brain)
Term
Meth and structural changes
Definition
Loss greatest in the limbic system and the hippocampus, but hits all places.
Term
Physical changes from Shaken Baby Syndrome
Definition
1) Lethargic nerve - connects eye to brain - muscles around eye will tear - lethargic eyes

2) Pale or blue skin
Term
SBS structural changes
Definition
Meninges - tearing - affects blood flow into brain

2) Tearing of the veins on the top of the brain
- This leads to hemorrhage, similar to what is observed in a stroke

Other foci of damage
include tearing the cranial nerves, shearing of the brainstem, and
damage to the optic nerve

The violent shaking in SBS results in TBI (traumatic brain injury) – percussive injury
Term
Lens
Definition
Focuses light and bends to accommodate near and far objects.
Term
Iris
Definition
No visual processing here. Opens and closes to allow more or less light in.
Term
Pupil
Definition
The hole in the iris.
Term
Retina
Definition
Light sensitive, contains neurons and photoreceptor cells.
Term
Fovea
Definition
Region at center of retina, best vision
Term
Cornea
Definition
Clear outer covering
Term
Blind spot or optic disc
Definition
Region of the retina where axons forming the optic nerve leave the eye and where blood vessels enter and leave

This region has no photoreceptors
Term
Optic chiasm
Definition
Point at which visual information switches over (every sense switches over except taste)
Term
How is visual information processed?
Definition
The components of the eye are used to condense and focus this information onto the retina

2) From the retina, information is transmitted to the brain

3)Cells int he retina send info via their axons to the LGN or superior coll - then these send info back down axons to the visual cortex.
Term
Rods
Definition
1) More numerous than cones
2) Sensitive to low levels of light (dim light)
3) Used mainly for night vision
4) Not specialized for color
5) information from a relatively large number of rods converge on a relatively small number of ganglion cells
Term
Cones
Definition
1) Highly responsive to bright light
2) Specialized for color and high visual acuity
3) Mostly in the fovea (no rods in fovea)
4) Three types: green red and blue
Term
Blind spot or optic disc
Definition
he Optic Disc represents the beginning of the optic nerve (second cranial nerve) and is the point where the axons of retinal ganglion cells come together

Also the entry point for the major blood vessels that supply the retina
Term
Photoreceptors
Definition
The actual cellular units used to respond to the wave information.
Term
Fact about visual processing:
Definition
Topographic Organization is maintained throughout the reception and processing of visual information
Term
Ventral stream
Definition
What - temporal lobe - hippocampus - memories - where history is.
Term
Dorsal stream
Definition
Where - parietal lobe - perceptive - somatosensory area
Term
More steps of visual processing
Definition
1) Once information arrives in the primary visual cortex, it is sent out for more advanced processing

2) The What and Where visual streams are examples of the second level of processing
- Dominance columns are also found in this system
- Topography is always maintained
Term
Anopia
Definition
Generic definer of injury to visual cortex
Term
Hemianopia
Definition
Half of vision lost
Term
Quadrinopoia
Definition
- lose a quarter of visual field.
Term
Scotoma
Definition
An area of loss or impairment of visual acuity surrounded by a field of normal or relatively well-preserved vision. (Black dot)
Term
Visual-form agnosia
Definition
Damage to ventral (what) stream. Can draw pictures from memory, but cannot recognize drawings or objects.
Term
Prosopagnosia
Definition
Damage to the ventral (what) stream - Disorder of face perception where the ability to recognize faces is impaired, while the ability to recognize other objects may be relatively intact
Term
Achromatopsia
Definition
Damage to ventral (what) stream. Congenital color vision disorder that results in the inability to perceive color AND to achieve satisfactory visual acuity at high light levels (typically exterior daylight)
Term
Damage to ventral (what) stream
Definition
Detecting movement: cannot see movement of objects

But, can make proper movements toward object
Term
Damage to the "where" stream
Definition
Cannot guide movements on the basis of visual information.
Term
Damage to the dorsal ("where") stream
Definition
Cannot guide movements on the basis of visual information.
Term
Ventral "what" visual components
Definition
Color, form (shape), movement. Separate processes
Term
Medial geniculate nucleus
Definition
Where sound is transformed
Term
Lateral geniculate nucleus
Definition
Where vision is transformed
Term
Generator potentials
Definition
local changes in membrane potential
Term
Sensory transduction
Definition
The conversion of electrical energy/physical energy from a stimulus into a change in the membrane potential in a receptor
Term
Somatosensation
Definition
Somatosensation
Deals with physical interactions from the environment upon sensory receptors
Includes touch/pressure, vibration, stretch, pain and temperature
The physical interaction is transformed to a change in the membrane potential
Local generator potentials add to attain threshold (like PSPs)
Term
Where do all sensory pathways terminate?
Definition
All pathways terminate in the cerebral cortex.
Term
Brainstem
Definition
Where sensory information switches sides - if heat at left foot, then brainstem will channel info to right hemisphere.
Term
Where the sensory homunculus is
Definition
Postcentral gyrus of the parietal lobe
Term
Neurocrine transmission
Definition
Hormone acting as a neurotransmitter - basic synaptic transmission
Term
Endocrine glands communication
Definition
Don’t need to touch - hormone secreted from a gland, enters the blood stream, and gets to target cell
Term
Neuroendocrine
Definition
Synapse controlling release of something to the bloodstream - what you have in the hypothalamus
Term
HPA axis
Definition
Stress --> Hypothalamus (CRF) --> Pituitary (ACTH) --> Adrenal (Cortisol)
Term
Gonads
Definition
Testes or ovary - produce gametes
Term
Congenital Adrenal Hyperlasia (CAH)-
Definition
Females exposed to high levels of androgens before birth.
- Develop an intersex appearance. Phallus intermediate between penis and clitoris and skin folds that resemble both labia and scrotum.
Term
Androgen Insensitivity Syndrome
Definition
XY males fail to produce functional androgen receptors. Develop a feminine phenotype.
Term
Aromatization hypothesis
Definition
Testicular androgens enter the brain and are converted there into estrogens, and these estrogens are what masculinize the developing nervous system.
Term
Aromatase
Definition
Converts testosterone into estradiol
Term
Locus Coeruleus
Definition
Brainstem nucleus involved in controlling physiological response to stress and panic. 
-Volume is greater in females than males.
Term
Male brain larger
Definition
SCN- Larger in males than females. Similar in females and TFM males.

Exist for integrative processing centers of the brain such as the hippocampus and cerebral cortex

Male more sensitive to pain is not because we have more receptors, but because brain regions associated with pain are more sensitive.
- Males - not because more visual receptors, but more neurons on the visual cortex.

SDN-POA- Larger in males than females. Similar in males and TFM males.
Term
Sex differences and the brain
Definition
No sex differences in the basic reception units such as the retina and thalamus
Term
Female brain larger
Definition
F>M neuron density in temporal cortex (language area)
Term
Pituitary
Definition
Regulates homeostasis and other glands
Term
Adrenal
Definition
Secrete glucocorticoids and testosterone
Term
Aromatization Hypothesis
Definition
The developing nervous system is masculinized by androgens being converted to estrogens in the brain
Testosterone is converted to estrogen by aromatase
Alpha-fetoprotein binds to estrogens and keeps them from entering the brain how you develop females
Term
Females rodents typically exhibit lordosis
Definition
Females rodents typically exhibit lordosis
Term
Male brains
Definition
Larger Hippocampal Volume
Larger INAH-3
Larger Brain Volume
More neurons in SDN-POA
More neurons in SNB
Larger neuron density in visual cortex
Term
Female brain
Definition
Larger Locus Coeruleus
Larger neuron density in temporal lobe
Term
Emotions (8)
Definition
Joy/Sadness
Affection/Disgust
Anger/Fear
Expectation/Surprise
Term
Folk Psychology
Definition
Stimulus--> perception --> emotional response --> physiological response
Term
James-Lange Theory
Definition
Stimulus -> perception -> physiological response -> emotions
Term
Cannon-Bard Theory
Definition
Stimulus -> perception -> Physiological and Emotional Response
Term
Schacter Theory
Definition
Emotions are a result of an interaction between the physiological response and the cognitive interpretation of the response.
Term
Neural circuitry of fear
Definition
Amygdala -
Group of nuclei located in the forebrain, part of the “limbic” system
Important for emotional processing of stimuli, and appears to be crucial to the fear response
Removed in Kluver-Bucy syndrome
Contains several subdivisions
Term
Long term stress effects
Definition
Hippocampal damage - increased glutamate which can cause more calcium to enter the cell which can kill neurons
Term
Declarative/explicit
Definition
Things you know (facts - thinks you can declare)
Term
Non-Declarative/Implicit/Procedural
Definition
Things you know that you can show by doing

Skills, classical conditioning, priming, non-associative learning.
Term
H.M.
Definition
Removed part of the temporal lobe, amydgala, hippocampus, and cerebellum to relieve epilepsy

Impaired Explicit/Declarative memory with intact Implicit

Displayed anterograde amnesia and can’t form long-term memories but can form short-term memories
Term
Retrograde amnesia
Definition
Memory loss before injury
Term
Anterograde amnesia
Definition
Memory loss after injury
Term
Korsakoff’s Syndrome
Definition
Retrograde amnesia and loss of neuron connections due to thiamine deficiency as a result of alcoholism
Term
Explicit memory regions
Definition
Involves medial temporal region with:
Hippocampus
Amygdala
Para-hippocampal cortices
mPFC
Term
Flow of information in explicit memory circuit
Definition
PHC -> Dentate Gyrus -> CA3 -> CA1 -> Fimbria/Fornix -> mPFC
Term
Implicit memory structure
Definition
Input -> Neocortex -> Substantia Nigra/Basal Ganglia -> Ventral Lateral Thalamus -> Pre-motor cortex

Largely unconscious because the flow of information from the cortex to the Basal Ganglia in unidirectional
Term
Humans have above average senses of:
Definition
sound, vision, and smell
Term
Amygdala
Definition
Amygdala is part of the limbic system and important for emotional processing like with the fear response and empathy . Also adds emotional and stress response to memories and sends it to other regions of the brain
Amygdala has 3 subdivisions; lateral, central, and baso-lateral
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