Term
| Generic Name for Oral Contraceptives |
|
Definition
Ovcon 35
Neucon 1/35
Ortho-novum |
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|
Term
| Action of Oral Contraceptives |
|
Definition
Decrease fertility by:
- inhibiting ovulation
-thickening cervical mucus
-making lining of endometrieum less favorable for implantation |
|
|
Term
Side effects of Oral Contraceptives
(Ovcon, Necon 1/35, ortho-novum |
|
Definition
1. HTN
2. Breakthrough bleeding
3. Thromboembolic events (MI, PE--> STOP SMOKING)
4. Cervical Cancer (HPV risk; papsmear) |
|
|
Term
| Drugs that decrease the effectiveness of oral contraceptives |
|
Definition
-ampicillin
-tetracycline
-carbamazepine
-phenobarbital
-phenytoin |
|
|
Term
| Oral contraceptives decrease the effectiveness of which drugs? |
|
Definition
Oral hypoglycemics
Warfarin |
|
|
Term
| What should you encourage to patients taking oral contraceptives? |
|
Definition
-take pill same time each day
-STOP smoking |
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|
Term
| Generic name for progesterones |
|
Definition
medroxyprogesterone acetate (Provera)
norethindrone (Micronor)
megestrol acetate (Megace) |
|
|
Term
|
Definition
-induces favorable environment for:
- fetal growth & development
-maintain pregnancy |
|
|
Term
| Drop in progesterone levels results in _____ |
|
Definition
|
|
Term
|
Definition
-counters adverse effects of estrogen in HRT:
1. dysfunctional uterine bleeding
2. Amenorrhea d/t hormonal imbalance
3. Endometriosis
4. Endometrial carcinoma |
|
|
Term
|
Definition
1. Breast cancer (AVOID administration)
2. Thromboembolic events
3. Breakthrough bleeding
4. Edema |
|
|
Term
Crabamazepine
Phenobarbital
phenytoin
rifampin |
|
Definition
| contraceptive effectiveness decrease with the use of these drugs |
|
|
Term
| Client Teaching for Progesterone |
|
Definition
| -anticipate withdrawal bleeding 3-7 days after stopping medications |
|
|
Term
| Evidence of progesterone effectiveness: |
|
Definition
-restoration of hormonal balance with control of uterine bleeding
-restoration of menses
-decrease in endometrial hyperplasia in postmenopausal women receiving estrogen
-controls spread of endometrial cancer |
|
|
Term
|
Definition
conjugated equine estrogens (Premarin)
Estradiol |
|
|
Term
| What is estrogen needed for? |
|
Definition
-female growth/reproduction & traits
-block bone resorption
-decrease LDL
-suppress FSH (FSH needed for conception) |
|
|
Term
|
Definition
-contraception
-post menopause
-osteoporosis
-prostate cancer
-uterine bleeding/endometriosis |
|
|
Term
|
Definition
1. Endometrial/ovarian cancer
--> give with progesterone; biopsy q2 years
2. Risk of estrogen dependent breast CA
--> self breast exams
3. Embolic events
4, Males = gyncocomastia, impotence, penile atophy |
|
|
Term
| Interaction of estrogen and warfarin |
|
Definition
1. Estrogen decreases warfarin effectiveness
--> may need to INCREASE warfarin levels |
|
|
Term
| T/F Phenytoin increases estrogen toxicity |
|
Definition
|
|
Term
|
Definition
-required for growth and maturation of male sex organs
-promotes skeletal muscle growth (anabolic steroid effect) in sexually mature males |
|
|
Term
Uses for testosterone
-fluoxymesterone (Halostestin)
-danazol (Danocine) |
|
Definition
-hypogonadism
-delayed puberty
-pallative tx for breast cancer |
|
|
Term
|
Definition
1. CV (increase LDL, decrease HDL, edema)
2. Hepatoxcity
3. Hypercalcemia (breast -ca)
4. Virilism effects: acne
-M= gyncomastia, impotence, priapism, acne
-F= deeper voice, hirtuism, menstraul irregulatiries |
|
|
Term
Testosterone and effects with:
Warfarin
Glucocorticoids
Oral Hypoglycemics |
|
Definition
increases effects: monitor for
-bleeding, anemia
-infection
-hypOglycemia |
|
|
Term
|
Definition
1. oxytocin
2. methylergonaovine |
|
|
Term
Action of uterine stimulants
(oxytocin, methyergonovine) |
|
Definition
| increase strength, frequency, length of uterine contraction |
|
|
Term
|
Definition
-induction of labor
-control of post partum bleeding
-fetal stress testing
-Intranasal = promotion of milk let down) |
|
|
Term
|
Definition
| -emergency intervention for serious postpartum hemorrhage |
|
|
Term
|
Definition
uterine rupture
-> magnesium sulfate on standby for relaxation of myometrium |
|
|
Term
| s/e of methylergonovine (Methergine) |
|
Definition
|
|
Term
| What medication should you avoid with uterine stimulatns (oxytocin) |
|
Definition
vasopressors. WHY?
- can lead to HTN |
|
|
Term
| How should uterine stimulants (oxytocin) be administered? |
|
Definition
infusion pump
-gradually increase flow rate by 1mu/min q 30 min |
|
|
Term
| What should you monitor with the administration of oxytocin? |
|
Definition
-fetal HR
-uterine hyperstimulation
(contractions longer than 60 sec
occurring q 2-3 minutes)
STOP INFUSION |
|
|
Term
|
Definition
-terbutaline sulfate (Brethine)
-magnesium sulfate
-ritodrine |
|
|
Term
|
Definition
selectively activates beta 2-adrenergic receptors (beta 2 adrenergic agonist) RESULTING in
-utereine smooth muscle relaxation |
|
|
Term
|
Definition
delay preterm labor
can be used up to 48 hrs
via IV/SC |
|
|
Term
|
Definition
delay preterm labor
can be used up to 48 hrs
via IV/SC |
|
|
Term
|
Definition
-tachycardia
-palpitations
-chest pain
-tremors
-anxiety
-ha |
|
|
Term
| What interaction does terbutaline have with androgen agonist/ |
|
Definition
-can cause concurrent additive effects
-monitor for tachycardia, tremors |
|
|
Term
|
Definition
can cause HTN
(monitor for HTN crisis) |
|
|
Term
| Beta blockers and androgen |
|
Definition
| -monitor for negation of effects |
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