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Reproduction
eemb 156 MT1 female
45
Biology
Undergraduate 4
07/18/2007

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Term
in females where is inhibin secreted from and what stimulates it?
Definition
FSH stimulates the Granulosa cell in the ovarian follicles
Term
when does inhibin A reach its peaks?
Definition
in the early/ mid follicular phase and again at ovulation
Term
when does inhibin B reach its peaks?
Definition
durring the mid-luteal phase
Term
how many egges does a female have at age 37?
Definition
27000
Term
what is the importance of the medulla
Definition
contains nerves and blood vessels
Term
what does the cortex of the overy do?
Definition
contain the oocytes
Term
fibriated funnel
Definition
- "finger like
- recieves eggs
Term
cervix
Definition
-muscular structure that protects the uterus and guards entrance to it
Term
what are the 2 main hormons in females?
Definition
estrogen and progesterone
Term
how many sperm get past the cervix into the uterus?
Definition
only 100,000
Term
what is the development pathway of an oocyte during the follicular phase?
Definition
1) primordial follicle - follicle surronded by granulosa cells
2) developing follicle - granulosa form more layers around follicle
3) pre antral follicle - theca interna surrounds the granulosa cells, and estrogen begins to be secreted
4) graffian follicle - antrum forms(fluid filled structure), theca externa forms and comulus oophorus
Term
theca externa
Definition
suporting cells that hold structure together, becasue the structure is so large it needs them
Term
Estrous
Definition
changes associated with mid cycle release of estrogen
- can be behavior change, or physical change
-
Term
how long is the follicular phase and what hormone is associated with it?
Definition
from day 5 to day 14
-estrogen production is increased
Term
corpus luteum
Definition
once the follicle is ovulated this is left behind
- theca interna migrate inside cell and from paraluteal cells
- produces progestserone
Term
endometerium
Definition
-stratum basilis
-stratum functionilis
Term
-stratum functionilis
Definition
- builds up and breaks down during menstruation
-contains spiral artery > cork screw arteries and glands develop and break down during every cycle of menstruation
-develops 15 days in cycle
Term
vaginal secretion timeline
Definition
day 4 - crystaline
day 10 - production of estrogen in high volume from secretion
day 14 - approach menstration about to ovulate . very thin watery secretion
-allows sperm to enter during ovulation
Term
how is body temperature indicative of ovulation?
Definition
-shortly after ovulation body temp drops
- then raises 1/2 - 1 degree if pregnacy occurs higher body temp is maintained
Term
why is progerterone needed for pregnancy?
Definition
it inhibits LH
Term
how does the corpus luteum degenerate?
Definition
progesterone is converted to pregnadiol
Term
HCG
Definition
- Human choronic gonadotropin
- peptide hormone produced by the implanted embryo
- pervents the destruction of the corpus leuteum
- maintains progesterone production
Term
what does FSH do during menstration?
Definition
it initiates follicular growth > affecting granulosa cells
Term
how long is LH needed for mataining luteal function
Definition
2 weeks unless pregnacy, then HCG takes over and mantains luteal
Term
FSH
Definition
-stimulats growth of immature gradfian fillicles
-- as follicle grows releases inhibin which shuts off production of FSH
-
Term
estrogens
Definition
-initiate formation of new layer of endometrium
-stimupate crypts in cervix to produce fertile cervical mucus
Term
where does fertilization occur?
Definition
fallopian tube
Term
LH
Definition
triggers ovulation
Term
what are the 5 phases of the menstral cycle?
Definition
1) menstral phase 1-4
2) follicular pahse 5-13
3) ovulation 14
4) luteal phase 15-26
5) ischemic phase 27-28
Term
what are the differences between western woman and desert woman?
Definition
-primative woman experianced 1/10 the cycles
Western Woman
-earlier menarche
- stretch in roporduction life span
- same anaugular cycle
-3-400cycles
-28 day cycle
Desert woman
-30-40 cycles in their whole life
-menarche around 16
-menapause at 45
-naturally begins to menstruate
-gets pregnant very fast
Term
estras
Definition
massive release of estrogen
Term
purineal luminescence
Definition
ovulation is determined by pregnancy
Term
female disorders (5)
Definition
1) endomeriosis - the lining and endometrium is found on the outside of the uterus. it builds up on the abdominal cavity
2) uterine fibroid - very painful swelling of the uterus
3) endometrial carcinoma - cancer caused by estrogen
4) ovarian cancer - # of cycles cause it
5) breast cancer
Term
if a woman has her first child young, she has a less likley chance to developing breast cancer.
Definition
true
Term
how many cabons do all estrogens have?
Definition
18
Term
what are the effects of estradiol during the follicular phase?
Definition
1)maintenance and developemnt of 2-sex organs
2)maintenance and developemnt of 2-sex characteristics (softer skin, breast development and growth, higher voice, and fat deposit around hips)
3)travels to the follicles to help stimulate oogenesis
4)inhibits the release of FSH from the anterior pituitary
5) stimulates proliferative phase of the endometrium in the uterus
6) causes the cervical mucus to become copius, watery ans hospitable to sperm
Term
effects of progesterone
Definition
1) rais body temp 1 degree
2) inhibits LH > no ovulation
3) stimulates secretory phase of endometrium
4) causescervical mucus to be come thick
Term
granulosa cells
Definition
aeromatize androgens with the stimulation of FSH
Term
what hormone is the precursor to all steroid hormones?
Definition
Delta-5-pregnenolone
Term
what converts delta-5-pregnenolone to progesterone in the human body?
Definition
3B-HSD
Term
what converts 17A-OH-pregnenolone to 17A-OH-progesterone in the human body?
Definition
3B-HSD
Term
what converts dehydroepiandrosterone to androstenedione in the human body?
Definition
3B-HSB
Term
what dictates which biosynthesis pathway taken?
Definition
the enzyme that acts first
Term
what is the delta 5 bio pathway?
Definition
Acetate -> cholesterol -(cleaved by mitochondria)-> Delta-5-pregnenolone -(17A-hydroxylase)-> 17A-OH-pregnenolone -(C17-C20 lyase)-> dehydroepiandrosterone(DHEA)
Term
what is the delta 4 bio pathway?
Definition
Acetate -> cholesterol -(cleaved by mitochondria)-> Delta-5-pregnenolone -(3B-HSB)-> progesterone -(17A-hydroxylase)-> 17A-OH-progesterone -(C17-C20-lyase)-> Androstenedione (-(17B-HSD)-> testosterone) or -(aromatase)-> 19-OH-Androstenedione -(aromatase)-> 19-O-Androstenedione -(aromatase)-> oestrone -(17B-HSD)-> oestradiol-17B(estrogen)
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