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Reproduction Tumors
Female Tumors
29
Bible Studies
Undergraduate 2
05/21/2012

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Cards

Term
Surface epithelial tumor
Watery fluid
single cyst with simple flat lining
Definition
Serous cystadenoma
Term
Surface epithelial tumor
Watery fluid
Complex cysts with thick shaggy lining
Definition
Serous cystadenocarcinoma
Term
Surface epithelial tumor
Mucus like fluid
single cyst with simple flat lining
Definition
Mucinous cystadenoma
Term
Surface epithelial tumor
Mucus like fluid
Complex cysts with thick shaggy lining
Definition
Mucinous Cystadenocarcinoma
Term
Surface epithelial tumor
Bladder like urothelium seen
Benign
Definition
Brenner Tumor
Term
Sex-cord stromal tumor
Associated with Miegs syndrome
Definition
Fibromas

Miegs syndrome: fibromas, pleural effusions, ascites
Term
Sex-cord stromal tumor
precocious puberty in girls
Definition
Granulosa cell tumor
Term
Bilateral ovarian mucinous tumor with signet ring cells
Definition
Krukenburg tumor
Term
Presents with bleeding and grape like protrusion from the vagina.
Definition
Sarcoma Botryoides tumor aka
Embryonal rhabdomyosarcoma
Term
Tumor composed of large cells with clear cytoplasms and central nuclei resembling oocytes
Definition
Dysgerminoma of ovary
Term
Germ cell tumor
Composed of trophoblasts and syncytiotrophoblasts
Mimics placental tissue, but villi are absent
Definition
Choriocarcinoma of ovary

Elevated HCG
Term
Germ cell tumor
Endodermal sinus tumor
Elevated AFP

Schiller duvalle bodies
Definition
Yolk Sac tumor of ovary

Schiller duvalle bodies: glomeruli/glimeruloid like tissue
Term
Germ cell tumor
bilateral
Fetal tissue (skin, hair, bone, gut, thyroid)
Definition
Teratoma

Can get immature tissue or somatic malignancy within teratoma

Can cause struma ovarii (teratoma with thyroid tissue) = hyperthyroidism
Term
Surface epithelial tumor
Ovarian tumor that arises from endometroid like glands
Definition
endometrioid tumors
Term
Massive amounts of mucus in the peritoneum
Due to mucinous tumor of the appendix
"Jelly Belly"
Definition
Pseudomyxoma peritonei
Term
Characterized by increased LH
excess androgen production, spills out to periphery to get converted to estrione
Estrione negatively feeds back to inhibit FSH
Definition
Polycystic ovarian disease
Term
Obese young woman with infertility, oligmoenorrhea, hirsitism
Definition
Polycystic ovarian disease

some patients develop type 2 diabetes due to insulin resistance
Term
Bacterial infection of endometrium due to retained products of conception
Definition
Acute endometritis
Term
Hyperplastic protrusion of endometrium.
abnormal uterine bleeding
Can arise as side effect of tamoxifen
Definition
Endometrial Polyp

Tamoxifen:anti estrogen effect on breast, pro estrogen effect on endometrium
Term
Presents as dysmenorrhea (pain during menstruation) and pelvic pain

Most common site of involvement is the ovary, which results in 'chocolate cyst'
Definition
Endometriosis
Endometrioma (when ovaries involved)

Glands and stroma outside of the uterine endometrial lining
Term
Endometriosis within the uterine myometrium
Definition
Adenomyosis
Term
Occurs as a consequence of unopposed estrogen classically seen in postmenopausal women
Most important predictor for progression to endometrial carcinoma
Definition
Endometrial hyperplasia
Term
Post-menopausal bleeding
Malignant proliferation of endometrial glands

'Endometrioid' histology

can be from 1) hyperplasia pathway 2) sporadic pathway
Definition
Endometrial carcinoma (hyperplasia pathway)
Term
Benign neoplastic proliferation of smooth muscle arising from myometrium

Common in premenopausal women
"MULTIPLE well defined white WHORLED MASSES"
Definition
Leiomyoma (fibroid)

"MULTIPLE well defined white WHORLED MASSES"
Term
Malignant proliferation of smooth muscle arising from myometrium

Arises de novo in postmenopausal women

"Single lesion with necrosis & hemorrhage"
Definition
Leiomyosarcoma

"Single lesion with necrosis & hemorrhage"
Term
Secondary amenorrhea due to excessive/overaggressive dilation and curretage
Definition
Asherman syndrome
Term
Post-menopausal bleeding
Malignant proliferation of endometrial glands

'serous and papillary structures'. Psammoma body formation on histology
Definition
Endometrial carcinoma (sporadic pathway)

A result of p53 mutation
Term
Sex cord stromal tumor
May produce androgen with hirsutism and virilization

Characteristic Reinke Crystals
Definition
Sertoli-Leydig cell tumor

Reinke crystal: crystallized testosterone
Term
Most common germ cell tumor of children
Definition
Yolk sac tumor
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