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Reproduction Tumors
Male Tumors
29
Art History
Undergraduate 1
05/21/2012

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Term
Inhibits cGMP phosphodiesterase

Smooth muscle relaxation corpus cavernosum
Definition
Sildenafil
Vardenafil

Beneficial effects on Raynaud

Side effects:
Impaired blue-green color vision

Risk of life threatening hypotension with nitrates
Term
Penile pathology associated with Gray solitary crusty plaque

a type of carcinoma in situ
Definition
Bowen's disease
Term
Penile pathology associated with Red velvety plaque, similar to bowen's disease
Definition
Erythroplasia of Queyrat
Term
Penile pathology associated with More common in asia, africa and south america. Associated with lack of circumcision
Definition
Squamous cell carcinoma

Also associated with high risk HPV (16,18)
Term
Penile pathology associated with cauliflower warts, associated with HPV 6,11
Definition
Condylomata accuminata
Term
Testicular germ cell tumor that:
malignant, painless, homogenous testicular enlargement
Most common testicular tumor

Affects males 15-35
Definition
Testicular seminoma

Affects males 15-35
Term
Testicular germ cell tumor that:
Malignant & Painful
Glandular/papillary morphology
Comprised of immature, primitive cells

Elevated AFP and hCG
Definition
Embryonal carcinoma
Term
Testicular germ cell tumor that:
Schiller duval bodies resemble primitive glomeruli
Elevated AFP
Definition
Yolk sac tumor (endodermal sinus)
Term
Testicular germ cell tumor that:
Malignant
Elevated hCG
Definition
Choriocarcinoma
Term
Testicular germ cell tumor that:
Malignant
Contains cells from multple germlines
Definition
Teratoma
Term
Testicular sex cord stromal tumor that:
Contains reinke cells
Golden brown color
Definition
Leydig cell tumor
Term
Testicular sex cord stromal tumor that:
Androblastoma from sex cord stroma
Definition
Sertoli Cell tumor
Term
Testicular non-germ cell tumor that:
Most common testicular cancer in old men, often bilateral
Definition
Testicular Lymphoma

Usually diffuse large B-cell type
Term
Testicular germ cell tumor that:
Looks like large cells in lobules with watery ctoplasm
"Fried egg" appearance
Radiosensitive
Definition
Testicular seminoma
Term
Testicular germ cell tumor that:
Disordered syncytiotrophoblastic and cytotrophoblastic elements
Definition
Choriocarcinoma
Term
Testicular non-germ cell tumor that:
Usually androgen producing
Causes gynomastia in men
precocious puberty in boys
Definition
Leydig cell
Term
Penile pathology:
Bent penis due to acquired fibrous tissue formation
Definition
Peyronie's disease
Term
Penile pathology associated with multiple reddish papules. Seen in younger patients relative to bowen disease and erythroplasia of queyrat
Does not progress to invasive carcinoma
Definition
Bowenoid papulosis
Term
Testicular germ cell tumor that:
Comprised of large cells with clear cytoplasm and central nuclei.
Forms homogenous mass with no hemorrhage or necrosis
Responds well to radiotherapy
Definition
Testicular seminoma

The male equivalent of dysgerminoma - instead of resembling oocytes, it resembles spermatogonia
Term
Testicular germ cell tumor that:
Can differentiate into another type of germ cell tumor with chemotherapy
Definition
Embryonal carcinoma
Term
Testicular germ cell tumor that:
Is the most common testicular tumor in children
AFP is often elevated
Definition
Yolk sac (endodermal sinus) tumor
Term
Testicular sex cord stromal tumor that:
Produces androgen, causing precocious puberty in children or gynecomastia in adults
Definition
Leydig cell tumor
Term
Testicular germ cell tumor that:
composed of placental like tissue without villi

Hormone produced can often lead to hyperthyroidism or gynecomastia
Definition
Choriocarcinoma

B-hCG similar to that of FSH, LH, and TSH
Term
Testicular germ cell tumor that:
Comprised of immature, primitive cells that may produce glands, forms a hemorrhagic mass with necrosis

Aggressive with early hematogenous spread, with AFP or B-hCG elevated.
Definition
Embryonal carcinoma
Term
Whats the diagnosis:
Hesitancy, dribbling, weak urinary stream, old man
Definition
BPH

Not correlated with progression to carcinoma
Term
Whats the diagnosis:
Hesitancy, dribbling, weak urinary stream, old age, back pain
Definition
Prostatic adenocarcinoma

Lump on posterior aspect of prostate on DRE
Term
Treatment for BPH
Definition
alph-antagonists:
Terazosin (BP effect)

Selective alpha1a antagonists:
Tamulosin (no BP effect)

5-alpha reductase inhibitor:
Finasteride
Dutasteride
Term
Treatment options for prostatic adenocarcinoma
Definition
Prostasectomy

Continuous GnRH agonist:
Leuprolide

DHT receptor antagonist:
Flutamide
Term
Unlike in females, this germ cell tumor is malignant in males
Definition
Teratoma
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