Term
primary amenorrhea is absence of period bytnormal 2nd sex char. by age_?
also could be absence of period but w/o the characterisitic by age_ |
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Definition
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Term
what is secodnary amenorrhea?
what age group is it more common in? |
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Definition
absence of menses for 3 cyles or 6 mo.
young- <25 yo |
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Term
| which type of amenorrhea is more common? |
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Definition
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Term
| most common female that has primary menorrhea is? |
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Definition
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Term
| what is the most commmon cause of amenorrhea |
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Definition
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Term
| 2nd amenorrhea caused by- 4 things |
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Definition
hypothalmic suppression
hyperprolactinemia
ovarian disorder
uterine disorder |
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Term
| what could cause hypothalmic suppression for amenorrhea? -3 |
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Definition
| weight loss, stress, PCOS |
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Term
| what could cause hyperprolactinemia for amenorrhea? 3 |
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Definition
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Term
| menses requires what 3 functional things? |
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Definition
| uterus and vagina and ovaries |
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Term
| primary amenorrhea can result from? -2 |
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Definition
congenital abnormality
imperforate hymen |
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Term
| 2nd amenorrhea can result from-2 |
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Definition
post surgery adhesion
abnormal uterine deveopmen |
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Term
| lack of follicle devlopment that causes amenorrhea can be caused by-2 |
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Definition
disease where estrogen production inadequate
chemotherapy |
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Term
| why does prolactin affect amenorrhea |
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Definition
| bc it supresses the HPG axis and prevents menses |
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Term
| how does hypothyroidism cause amenorrhea |
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Definition
| elevated TRH->increased prolactin |
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Term
how does breast feeding cause amenorrhea?
preggo? |
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Definition
more prolactin
more estrogen->more prolactin |
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Term
| what hormone naturally decrease prolactin? |
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Definition
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Term
| what hormone naturally increases prolactin |
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Definition
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Term
| what causes amernorrhea through the hypothalmus? |
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Definition
weight loss
intense exercise
stress
PCOS |
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Term
| what 3other things is PCOS associated with? |
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Definition
| insulin resistnace, obesity, metabolic syndrome |
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Term
PCOS is caused by over production of what in the ovaries?
this leads to what? |
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Definition
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Term
| PCOS anovulation results in what devlopement? |
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Definition
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Term
treatment for PCOS:
insulin problem:
reduce androgen effects: |
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Definition
metformin, TZDs
progesterone or contraceptives |
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Term
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Definition
| menstrual blood loss greater than 80 mL per cycle |
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Term
| menorrhagia causes are either- 2 things |
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Definition
systemic disorder
uterine abnormality |
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Term
| what is at the top of list for woman presenting with heay menses? -2 |
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Definition
preggo- intrauterine, ectopic
miscarriage |
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Term
| in adolescents with menorrhagia what is the majority of cause |
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Definition
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Term
| what is 1% incidence of menorrhagia |
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Definition
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Term
which med causes the most decrease in blood loss in menorrhagia?
what is its MOA? |
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Definition
NSAIDS
reduce prostoglandins in uterine contractions |
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Term
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Definition
| bleeding from endometrium as result of dysfunctional menstural system |
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Term
| what is the most common form of noncylci uterine bleeding? |
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Definition
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Term
| what is most common cause of anovulatory bleeding? |
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Definition
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Term
| when is anovulatory bleeding common |
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Definition
| within 5 years of menarche |
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Term
| what may show inhertied bleeding disorder for anovulatory bleeding? |
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Definition
| iregular menses with a lot of bleeding |
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Term
| when woman has excessvie bleeding with anovulatory cycles- what do you eval for?-2 |
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Definition
cancer
endometrial hyperplasia |
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Term
what is reccomended for acute anovulatory bleeding?
why? |
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Definition
estrogen
stabilizes endometrium |
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Term
| how do OCs prevent anovulatory bleeding? |
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Definition
| incldue progestin and supress androgen prodcution |
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Term
| for people with PCOS that causes anovulatory bleeding what meds cna be used? |
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Definition
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Term
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Definition
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Term
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Definition
| pain with underlying pelvic pathology |
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Term
| risk factors for dysmenorrhea- 5 |
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Definition
young
heavy menses
mulliparity
early menarche
cig smoke |
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Term
| 90% of dymenorrhea is what type? |
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Definition
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Term
| pathphys for primary dysmenorrhea |
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Definition
| prostoglandins in menstrual fluid |
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Term
| what leukotrienes are elevated in dysmenorrhea |
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Definition
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Term
| what 2 things must be considered in dysmenorrhea |
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Definition
| pregnancy and miscarriage |
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Term
first line treatment for dysmenorrhea?
other options? -3 |
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Definition
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Term
supression of what improves symtpoms of PMS/PMDD?
this shows relation to what hromone? |
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Definition
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Term
reduction in hormone for PMS/PMDD is caused by:
reduced allopregnalone in _ phase
reduced GABA in _ phase |
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Definition
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Term
| depression in PMS is caused by? |
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Definition
| reduction of serotonin or NE |
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Term
what antideppresents are used for PMS?
what are some side effects -4 |
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Definition
SSRI
sexual dysfunction, GI, insomnia, serotonin syndrome |
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Term
endometriosis means?
what is it assoicated with? |
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Definition
groth of endometrial tissue outside the uterus
pelivc pain and inferrtility |
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Term
| what tissue is most invovled with endometriosis |
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Definition
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Term
| what women should endometriosis be suspected in? |
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Definition
| dysmenorrhea or chronic pelvic pain |
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Term
| what is the more widely accepted theroy for endometriosis? |
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Definition
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Term
| what is the metastatic theory for endometriosis? |
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Definition
| endometrial tissue implanted by various mechanisms |
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Term
| what is the metaplastic theory for endometriosis? |
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Definition
| endometrial tissue aries directly mesothelium of pelvis or abdomen |
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Term
pain from endometrioisis caused by-3
what hromone enhances this pain, growth and inflamm? |
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Definition
local inflamm, bleeding, compressed nerves;
estogen |
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Term
| first line drugs for endometriosis-2 |
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Definition
| combnined hormonal contraceptives progestins |
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