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Pharm -- Renal
First Aid 2012 pp524-527
23
Medical
Graduate
02/05/2013

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Cards

Term
mannitol side effect
Definition
pulmonary edema
Term
urea
Definition
osmotic diuretic --> increased urine flow
Term
isosorbide
Definition
osmotic diuretic --> increased urine flow (used for increased intraocular pressure)
Term
glycerin
Definition
osmotic diuretic --> increased urine flow (used for increased intraocular pressure)
Term
dorzalomide
Definition
carbonic anhydrase inhibitor
Term
brinzolamide
Definition
carbonic anhydrase inhibitor
Term
bumetanide
Definition
loop diuretic
Term
torsemide
Definition
loop diuretic
Term
ethacrynic acid (and differences from other drugs in its class)
Definition
like loop diuretic
NOT sulfa drug!!
more ototoxicity, less hyperuricemia
Term
triamterene
Definition
K+ sparing diuretic
blocks sodium channel directly
Term
amiloride
Definition
K+ sparing diuretic
blocks sodium channel directly
Term
eplerenone
Definition
K+ sparing diuretic
aldosterone receptor antagonist
Term
carbonic anhydrase inhibitor side effects
Definition
acidosis, sulfa drug
Term
loop diuretic side effects
Definition
OH DANG!
ototoxocity
hypokalemia
dehydration
allergy (sulfa)
nephritis (interstitial)
gout
Term
thiazides side effects
Definition
hyperGLUC!
glucose
lipids
uric acid
calcium --> increased bone density!!

hypokalemia, hyponatremia, alkalosis
Term
K+ sparing diuretic side effects
Definition
hyperkalemia
anti-androgen effects (i.e. gynecomastia for aldosterone receptor antagonists)
Term
ACE inhibitor side effects
Definition
CAPTOPRIL
Cough
Angioedema
(no p)
Taste changes
hypOtension -- first dose!! esp if on diuretic!!
Pregnancy problems
Rash
Increased renin
Lower angiotensin II

hyperkalemia
do NOT use in bilateral renal artery stenosis
Term
ARB side effects
Definition
Taste changes
hypOtension -- first dose!! esp if on diuretic!!
Pregnancy problems
Rash
Increased renin
Increased angiotensin II

hyperkalemia
do NOT use in bilateral renal artery stenosis
Term
what do ACEi/ARBs do for the heart??
Definition
prevent remodeling from HTN
Term
how much increase in creatinine do you expect from ACEi/ARB??
Definition
30% in 2-5 days, then stabilize in 2-3 wks, reversible!!
Term
weird HCTZ indication
Definition
nephrogenic DI!!
Term
weird osmotic diuretic uses (2) and reasoning
Definition
shock, drug overdose --> to prevent acute renal failure
Term
continous leuprolide course
Definition
transient increase in androgens (start up flare), then decreased androgens
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