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Composed of kidneys; major route to eliminate drugs; produces hormones; regulates body fluid and electrolyte balance |
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Disease characterized by overproduction/insufficent elimination of uric acid, allowing it to crystalize in joints, causing inflammation and pain |
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Salts dissolved in body fluids; proper concentration necessary for homeostasis; prescribed to replace depleted salts
SE: stomach upset, constipation, and diarrhea |
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| Used to treat CHF, htn, fluid retention (edema); Alters the body's electrolyte pattern by prohibiting or enhancing excretion of electrolytes |
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Caused by most diuretics; corrected by injestion of high-potassium foods (OJ, bananas), or by taking a potassium-sparing diuretic |
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Reduce BP; causes kidneys to secrete more, decreasing water retention and BP
SE: Increased urination, weakness, muscle cramps, stomach upset, and dizziness |
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Hydrochlorothiazide (Hydrodiuril) |
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Tx CHF; potent diuretic
SE: Increased urination, weakness, muscle cramps, stomach upset, and dizziness |
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Ethacrynic acid (Edecrin) |
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Potassium-Sparing Diuretics |
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Tx CHF; weak diuretics, often used in combination c other diuretics; no potassium supplement needed
SE: increased urination, weakness, muscle cramps, stomach upset, and dizziness |
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Spironolactone (Aldactone) |
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Potassium-Sparing Diuretic |
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Potassium-Sparing Diuretic |
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Potassium-Sparing Diuretic |
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Amiloride + HCTZ (Moduretic) |
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Triamterene + HCTZ (Maxzide, Dyazide) |
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Used to produce an intense diuresis in a hospital setting; pulls water out of the body and into the kidneys |
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Prevent and tx gout attack |
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Gout agent; used to inhibit uric acid production
SE: Rash |
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Gout agent; enhances excretion of uric acid
SE: Kidney stones |
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Gout agent; drug of choice for acute attacks; reduces pain and swelling of gout flares
SE: Gastrointestinal complaints |
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