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Renal Cell Carcinoma
Renal Cell Carcinoma
8
Bartending
Professional
11/30/2012

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Cards

Term
Renal Cell Carcinoma Risk Factors
Definition
-smoking
-obesity
-HTN
-family
-Von Hippel-Lindau Syndrome
Term
IL-2
Definition
-stimulates endogenous immunity
-toxic-can't be used in older patients
SE-hyoptension, renal failure, mental status changes, N/V, diarrhea, dyspnea
Term
sorafenib (Nexavar)
Definition
-inhibits angiogensis
AE-rash, hand-foot syndrome, diarrhea, hypertension
Term
sunitinib (Sutent)
Definition
-rash, hand-foot syndrome, hypertension, diarrhea, dry skin, GIII-IV neutropenia
BLACK BOX-hepatotoxicity, dec. LVEF, inc. QT, bleeding, proteinuria , wound healing
Term
Temsirolimus (Torisel)
Definition
targets angiogenesis
AE-rash, stomatitis, hyperglycemia, hyperlipidemia
Term
Pazopanib (Votrient)
Definition
targets angiogenesis
-hepatotoxicity, dec. LVEF, prolonged QT, proteinuria, inhibits wound healing, bleeding
Term
Everolimus (Afinitor)
Definition
-targets angiogensis
Term
Axitinib (Inlyta)
Definition
inhibits angiogensis
AE-Hepatotxicity, HTN, hypothyroidism, wound healing, proteinuria, bleeding
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