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Reduction of Benzil
Reduction of Benzil
13
Organic Chemistry
Undergraduate 2
06/11/2019

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Term
reduction
Definition
increase amount of bonds to H or decrease amount of bonds to O
Term
general mechanism for reduction
Definition
[image]
Term
2 of the most common reducing agents
Definition
-LiAlH4 (LAH) -NaBH4
Term
disadvantage of LAH
Definition
extremely reactive such that it's incompatable with aqueous solvents and can catch fire
Term
the type of solvent that must be used with LAH
Definition
ethereal solvents
Term
advantages of NaBH4
Definition
-safe and more mild
-can be used with aqueous solvents
Term
the reducing agent that will be used in this lab
Definition
NaBH4
Term
more specific mechanism for this lab
Definition
[image]
Term
a big no-no with NaBH4
Definition
adding it to the mixture too fast; if you do this, it'll fizz
Term
why LiAlH4 and NaBH4 can be used as reducing agents
Definition
because they serve as a source of hydride anions (H-)
Term
which reducing agent is more powerful: LiAlH4 or NaBH4
Definition
LiAlH4
Term
mechanism for reduction using NaBH4
Definition
[image]
Term
the rxn with NaBH4 continues happening until...
Definition
all the hydride anions get transferred onto a carbonyl moiety
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