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Rau's Resp. Care Pharmacology - Ch. 5,6
Rau's Resp. Care Pharmacology - Ch. 5,6
34
Pharmacology
Undergraduate 1
09/28/2011

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Term
Adrenergic (adrenomimetic):
Definition

mimic fight-or-flight sympathetic

stimulatie receptor for norepinephrine or epinephrine

Term
Antiadrenergic:
Definition

blocks sympathetic

blocking a receptor for norepinephrine or epinephrine

Term
Cholinergic (cholinomimetic):
Definition

mimics parasympathetic (involuntary)

stimulation of a receptor for acetylcholine

Term
Anticholinergic:
Definition

blocks parasympathetic (involuntary)

blocking a receptor for acetylcholine

Term
Cholinoceptor:
Definition
alternative term for cholinergic receptor
Term
Adrenoceptor:
Definition
alternative term for adrenergic receptor
Term
Parasympathomimetic
Definition

Mimics involuntary system

Cholinergic

Term
Parasympatholytic
Definition

Blocks Parasympathic effects

Anticholinergic

Term
Sympathomimetic
Definition

Mimics Sympathic (fight-or-flight) system

Adrenergic

Term
Sympatholytic
Definition

Blocks (fight-or-flight) sympathic NS

Antiadrenergic

Term
Muscarinic
Definition

cholinergic receptors at parasympathetic end sites

opposite

Term
Muscarinic receptor subtypes
Definition

M1 through M5

M2 receptors in the heart

M3 receptors mediating bronchoconstriction

Term
Sympathetic effects on the cardiopulmonary system
Definition
increased heart rate and contractile force
increased blood pressure
bronchodilation
increased secretion from mucous glands
Term
Parasympathetic (involuntary) effects on cardiopulmonary system
Definition

decreased heart rate

lower blood pressure

bronchoconstriction

mucous secretion

Term
Uses and Effects of Parasympatholytic (Antimuscarinic) Agents
Definition
Bronchodilation
Term
α Receptors:
Definition
Excite (except intestine)
Term
Alpha-1 (α1)
Definition
Peripheral blood vessels
Term
Alpha-2 (α2)
Definition
Presynaptic sympathetic neurons (autoreceptor)
Term
β Receptors:
Definition
Inhibit/relax (exception heart - stimulated)
Term
β1 Receptors:
Definition
Increase heart rate/force
Term
Beta-2 (β2)
Definition

Relax:

Smooth muscle

bronchial muscle

cardiac muscle

Term
Epinephrine
Definition

Adrenalin Cl

Epinephrine Mist

Primatene Mist

Term
Racemic epinephrine
Definition

microNefrin

Nephron

S2

Term
Isoetharine
Definition
Isoetharine HCl
Term
Metaproterenol
Definition
Alupent
Term
Albuterol
Definition

Proventil

Ventolin

ProAir

AccuNeb

Term
Pirbuterol
Definition
Maxair Autohaler
Term
Levalbuterol
Definition

Xopenex

Xopenex HFA

Term
Salmeterol
Definition
Serevent
Term
Formoterol
Definition
Foradil
Term
Arformoterol
Definition
Brovana
Term
Ultra-Fast Acting
Definition
<3 hours
Epinephrine
isoproterenol
isoetharine
Term
Short-acting
Definition

4–6 hours

Albuterol

levalbuterol

metaproterenol

pirbuterol

terbutaline

Term
Long-acting
Definition

12 hours

Salmeterol

formoterol

arformeterol

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